(Q34774167)

4 August 2017

title

Higher intensity of purifying selection on >90% of the human genes revealed by the intrinsic replacement mutation rates (English)

1 reference

4 August 2017

1

1 reference

4 August 2017

Sudhir Kumar

2

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publication date

18 September 2006

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Molecular Biology and Evolution

4 August 2017

published in

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4 August 2017

volume

23

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4 August 2017

issue

12

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4 August 2017

page(s)

2283-2287

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A genome-wide analysis of CpG dinucleotides in the human genome distinguishes two distinct classes of promoters

4 August 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3072915

Large-scale structure of genomic methylation patterns

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3072915

Natural selection on protein-coding genes in the human genome

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3072915

Evidence for selection on synonymous mutations affecting stability of mRNA secondary structure in mammals

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3072915

Initial sequence of the chimpanzee genome and comparison with the human genome

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3072915

A scan for positively selected genes in the genomes of humans and chimpanzees

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3072915

Weak selection revealed by the whole-genome comparison of the X chromosome and autosomes of human and chimpanzee

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3072915

CpG mutation rates in the human genome are highly dependent on local GC content

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3072915

Bayesian Markov chain Monte Carlo sequence analysis reveals varying neutral substitution patterns in mammalian evolution

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3072915

The signature of selection mediated by expression on human genes

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3072915

An evolutionary approach reveals a high protein-coding capacity of the human genome

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3072915

Neutral Substitutions Occur at a Faster Rate in Exons Than in Noncoding DNA in Primate Genomes

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3072915

Selection on Human Genes as Revealed by Comparisons to Chimpanzee cDNA

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3072915

Covariation in frequencies of substitution, deletion, transposition, and recombination during eutherian evolution

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3072915

Codon-substitution models for detecting molecular adaptation at individual sites along specific lineages

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3072915

Statistical methods for detecting molecular adaptation

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3072915

Patterns of single-nucleotide polymorphisms in candidate genes for blood-pressure homeostasis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3072915

Neighboring-nucleotide effects on the rates of germ-line single-base-pair substitution in human genes

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3072915

Molecular evolution of mRNA: a method for estimating evolutionary rates of synonymous and amino acid substitutions from homologous nucleotide sequences and its application

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3072915

Preponderance of synonymous changes as evidence for the neutral theory of molecular evolution

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3072915

Why do human diversity levels vary at a megabase scale?

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3072915

The covariation between TpA deficiency, CpG deficiency, and G+C content of human isochores is due to a mathematical artifact.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3072915

Evidence for Purifying Selection Against Synonymous Mutations in Mammalian Exonic Splicing Enhancers

26 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/16982819

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Distribution of the strength of selection against amino acid replacements in human proteins

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/16982819

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

MOLECULAR BIOLOGY:DNA Methylation de Novo

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/16982819

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1093/MOLBEV/MSL123

1 reference

4 August 2017

1 reference

4 August 2017

1 reference