(Q34774347)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12163126%20AND%20SRC:MED&resulttype=core&format=json

11 November 2019

title

Assessing the (a)symmetry of concentration-effect curves: empirical versus mechanistic models (English)

1 reference

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11 November 2019

1

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11 November 2019

author name string

Nuria M Vivas

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12163126%20AND%20SRC:MED&resulttype=core&format=json

11 November 2019

Elisabet Vila

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12163126%20AND%20SRC:MED&resulttype=core&format=json

11 November 2019

Albert Badia

series ordinal

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12163126%20AND%20SRC:MED&resulttype=core&format=json

11 November 2019

publication date

1 July 2002

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12163126%20AND%20SRC:MED&resulttype=core&format=json

Pharmacology & Therapeutics

11 November 2019

published in

1 reference

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11 November 2019

volume

95

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11 November 2019

issue

1

1 reference

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11 November 2019

page(s)

21-45

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12163126%20AND%20SRC:MED&resulttype=core&format=json

The slope parameter of concentration-response curves used as a touchstone for the existence of spare receptors.

11 November 2019

cites work

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7 January 2021

Dopamine D2 receptor dimer formation: evidence from ligand binding

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7 January 2021

A personal view of pharmacology

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7 January 2021

An operational model of pharmacological agonism: the effect of E/[A] curve shape on agonist dissociation constant estimation

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7 January 2021

Oligomerization of G-protein-coupled transmitter receptors.

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7 January 2021

Cardiac muscarinic receptors. Cooperativity as the basis for multiple states of affinity.

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7 January 2021

Binding, gating, affinity and efficacy: the interpretation of structure-activity relationships for agonists and of the effects of mutating receptors

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7 January 2021

Interaction at End-Plate Receptors between Different Choline Derivatives

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7 January 2021

Mathematical analysis of the control of neurotransmitter release by presynaptic receptors as a supplement to experimental data

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7 January 2021

Uncovering molecular mechanisms involved in activation of G protein-coupled receptors

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7 January 2021

The slope parameter and the receptor reserve

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7 January 2021

On the Nature of the Function Expressive of the Law of Human Mortality, and on a New Mode of Determining the Value of Life Contingencies

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7 January 2021

Cardiac muscarinic receptors. Relationship between the G protein and multiple states of affinity

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7 January 2021

Ligand Competition Curves as a Diagnostic Tool for Delineating the Nature of Site-Site Interactions: Theory

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7 January 2021

Muscarinic inhibition of endogenous noradrenaline release from rabbit isolated trachea: receptor subtype and receptor reserve

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7 January 2021

Finding affinity constants for agonists by the irreversible antagonists method

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7 January 2021

Differences between natural and recombinant G protein-coupled receptor systems with varying receptor/G protein stoichiometry

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7 January 2021

Protein affinities for small molecules: Conceptions and misconceptions

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7 January 2021

Assessment of a ternary model for the binding of agonists to neurohumoral receptors

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7 January 2021

Estimation of agonist affinity and efficacy by direct, operational model-fitting.

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7 January 2021

A three-state receptor model of agonist action

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7 January 2021

Constitutive activity of receptors coupled to guanine nucleotide regulatory proteins

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7 January 2021

Properties of human glycine receptors containing the hyperekplexia mutation alpha1(K276E), expressed in Xenopus oocytes.

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7 January 2021

Concentration-response curves and receptor classification: null method or operational model?

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7 January 2021

The effect of the molecular mechanism of G protein-coupled receptor activation on the process of signal transduction

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7 January 2021

A Flexible Growth Function for Empirical Use

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7 January 2021

Modelling the changes due to the endothelium and hypertension in the alpha-adrenoreceptor-mediated responses of rat aorta.

1 reference

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7 January 2021

Dimerization of G-protein-coupled receptors: implications for drug design and signaling

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https://api.crossref.org/works/10.1016%2FS0163-7258%2802%2900223-1

7 January 2021

Analysis of asymmetry of agonist concentration-effect curves

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7 January 2021

Use of the operational model of agonism and [3H]prazosin binding to assess altered responsiveness of α1-adrenoceptors in the vas deferens of spontaneously hypertensive rat

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7 January 2021

The cubic ternary complex receptor-occupancy model. III. resurrecting efficacy

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7 January 2021

10.1016/S0163-7258(02)00223-1

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12163126%20AND%20SRC:MED&resulttype=core&format=json

11 November 2019

1 reference