(Q34774620)

English

The human antimicrobial peptide LL-37 binds directly to CsrS, a sensor histidine kinase of group A Streptococcus, to activate expression of virulence factors

scientific article

In more languages

Statements

scholarly article

1 reference

Europe PubMed Central

4 August 2017

The human antimicrobial peptide LL-37 binds directly to CsrS, a sensor histidine kinase of group A Streptococcus, to activate expression of virulence factors (English)

1 reference

Europe PubMed Central

4 August 2017

antimicrobial peptide

1 reference

based on heuristic

inferred from title

author name string

Jorge J Velarde

1

1 reference

Europe PubMed Central

4 August 2017

Melissa Ashbaugh

2

1 reference

Europe PubMed Central

4 August 2017

Michael R Wessels

3

1 reference

Europe PubMed Central

4 August 2017

language of work or name

0 references

publication date

6 November 2014

1 reference

Europe PubMed Central

4 August 2017

Journal of Biological Chemistry

1 reference

Europe PubMed Central

4 August 2017

289

1 reference

Europe PubMed Central

4 August 2017

52

1 reference

Europe PubMed Central

4 August 2017

36315-36324

1 reference

Europe PubMed Central

4 August 2017

Streptolysin O and its co-toxin NAD-glycohydrolase protect group A Streptococcus from Xenophagic killing.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4276891

7 July 2018

Inactivation of the CovR/S virulence regulator impairs infection in an improved murine model of Streptococcus pyogenes naso-pharyngeal infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4276891

7 July 2018

A comprehensive summary of LL-37, the factotum human cathelicidin peptide.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4276891

7 July 2018

Vitamin D and the human antimicrobial peptide LL-37 enhance group a streptococcus resistance to killing by human cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4276891

7 July 2018

A bacterial pathogen co-opts host plasmin to resist killing by cathelicidin antimicrobial peptides

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4276891

7 July 2018

Rot and SaeRS cooperate to activate expression of the staphylococcal superantigen-like exoproteins.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4276891

7 July 2018

Signal transduction through CsrRS confers an invasive phenotype in group A Streptococcus.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4276891

7 July 2018

Molecular insight into invasive group A streptococcal disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4276891

7 July 2018

M1 protein allows Group A streptococcal survival in phagocyte extracellular traps through cathelicidin inhibition

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4276891

7 July 2018

Highly frequent mutations in negative regulators of multiple virulence genes in group A streptococcal toxic shock syndrome isolates

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4276891

7 July 2018

The chemistry and biology of LL-37

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4276891

7 July 2018

CovS simultaneously activates and inhibits the CovR-mediated repression of distinct subsets of group A Streptococcus virulence factor-encoding genes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4276891

7 July 2018

Induction of group A Streptococcus virulence by a human antimicrobial peptide

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4276891

7 July 2018

Structures of human host defense cathelicidin LL-37 and its smallest antimicrobial peptide KR-12 in lipid micelles

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4276891

7 July 2018

Cathelicidin LL-37 in severe Streptococcus pyogenes soft tissue infections in humans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4276891

7 July 2018

NMR structure of the cathelicidin-derived human antimicrobial peptide LL-37 in dodecylphosphocholine micelles

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4276891

7 July 2018

The two faces of Janus: virulence gene regulation by CovR/S in group A streptococci

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4276891

7 July 2018

LL-37, the only human member of the cathelicidin family of antimicrobial peptides

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4276891

7 July 2018

Genome-wide analysis of group a streptococci reveals a mutation that modulates global phenotype and disease specificity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4276891

7 July 2018

Salivary antimicrobial peptide expression and dental caries experience in children

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4276891

7 July 2018

Expression and modulation of LL-37 in normal human keratinocytes, HaCaT cells, and inflammatory skin diseases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4276891

7 July 2018

Sensing external stress: watchdogs of the Escherichia coli cell envelope

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4276891

7 July 2018

Impact of LL-37 on anti-infective immunity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4276891

7 July 2018

Contribution of CsrR-regulated virulence factors to the progress and outcome of murine skin infections by Streptococcus pyogenes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4276891

7 July 2018

The CsrR/CsrS two-component system of group A Streptococcus responds to environmental Mg2+

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4276891

7 July 2018

Virulence control in group A Streptococcus by a two-component gene regulatory system: global expression profiling and in vivo infection modeling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4276891

7 July 2018

Proteinases of common pathogenic bacteria degrade and inactivate the antibacterial peptide LL-37.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4276891

7 July 2018

Impact of single-residue mutations on the structure and function of ovispirin/novispirin antimicrobial peptides

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4276891

7 July 2018

Innate antimicrobial peptide protects the skin from invasive bacterial infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4276891

7 July 2018

Spontaneous mutations in the CsrRS two-component regulatory system of Streptococcus pyogenes result in enhanced virulence in a murine model of skin and soft tissue infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4276891

7 July 2018

Two-component signal transduction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4276891

7 July 2018

Expression of Staphylococcus aureus clumping factor A in Lactococcus lactis subsp. cremoris using a new shuttle vector

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4276891

7 July 2018

Hyaluronic acid capsule and the role of streptococcal entry into keratinocytes in invasive skin infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4276891

7 July 2018

Identification of csrR/csrS, a genetic locus that regulates hyaluronic acid capsule synthesis in group A Streptococcus.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M114.605394

21 January 2018

Solution structures of human LL-37 fragments and NMR-based identification of a minimal membrane-targeting antimicrobial and anticancer region.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M114.605394

21 January 2018

Lipid segregation explains selective toxicity of a series of fragments derived from the human cathelicidin LL-37.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M114.605394

21 January 2018

Efficient protein production method for NMR using soluble protein tags with cold shock expression vector

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M114.605394

21 January 2018

Mg2+ signalling defines the group A streptococcal CsrRS (CovRS) regulon

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M114.605394

21 January 2018

The human antimicrobial peptide LL-37 and its fragments possess both antimicrobial and antibiofilm activities against multidrug-resistant Acinetobacter baumannii

1 reference

https://pubmed.ncbi.nlm.nih.gov/25378408

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Salivary levels of antimicrobial peptides Hnp 1-3, Ll-37 and S100 in Behcet's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/25378408

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

SIC, a secreted protein of Streptococcus pyogenes that inactivates antibacterial peptides

1 reference

https://pubmed.ncbi.nlm.nih.gov/25378408

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1074/JBC.M114.605394

1 reference

Europe PubMed Central

4 August 2017

1 reference

Europe PubMed Central

4 August 2017

1 reference

Europe PubMed Central

4 August 2017

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q34774620&oldid=2120982071"