(Q34774635)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23771823%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

title

A high-throughput splicing assay identifies new classes of inhibitors of human and yeast spliceosomes (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23771823%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

0 references

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23771823%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

author name string

Kerstin A Effenberger

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23771823%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

Rhonda J Perriman

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23771823%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

Walter M Bray

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23771823%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

R Scott Lokey

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23771823%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

Melissa S Jurica

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23771823%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

publication date

14 June 2013

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23771823%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

number of pages

11

1 reference

Journal of Biomolecular Screening

inferred from page(s)

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23771823%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

volume

18

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23771823%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

issue

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23771823%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

page(s)

1110-1120

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23771823%20AND%20SRC:MED&resulttype=core&format=json

describes a project that uses

3 March 2020

ImageQuant

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3902173/fullTextXML

inferred from PubMed Central ID database lookup

cites work

Evolution and impact of subclonal mutations in chronic lymphocytic leukemia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3902173

The development and application of small molecule modulators of SF3b as therapeutic agents for cancer.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3902173

Psoromic acid derivatives: a new family of small-molecule pre-mRNA splicing inhibitors discovered by a stage-specific high-throughput in vitro splicing assay

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3902173

A quantitative high-throughput in vitro splicing assay identifies inhibitors of spliceosome catalysis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3902173

Exome sequencing identifies recurrent mutations of the splicing factor SF3B1 gene in chronic lymphocytic leukemia

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3902173

Somatic SF3B1 mutation in myelodysplasia with ring sideroblasts

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3902173

Frequent pathway mutations of splicing machinery in myelodysplasia

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3902173

The spliceosome: design principles of a dynamic RNP machine

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3902173

The biflavonoid isoginkgetin is a general inhibitor of Pre-mRNA splicing

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3902173

Spliceostatin A targets SF3b and inhibits both splicing and nuclear retention of pre-mRNA.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3902173

Apoptosis and inactivation of the PI3-kinase pathway by tetrocarcin A in breast cancers

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3902173

The NCI60 human tumour cell line anticancer drug screen

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3902173

Pladienolides, new substances from culture of Streptomyces platensis Mer-11107. III. In vitro and in vivo antitumor activities

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3902173

A Simple Statistical Parameter for Use in Evaluation and Validation of High Throughput Screening Assays

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3902173

ATP can be dispensable for prespliceosome formation in yeast

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3902173

Resolution of the mammalian E complex and the ATP-dependent spliceosomal complexes on native agarose mini-gels

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3902173

CUS2, a yeast homolog of human Tat-SF1, rescues function of misfolded U2 through an unusual RNA recognition motif

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3902173

Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3902173

Splicing of adenovirus RNA in a cell-free transcription system

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3902173

Lariat RNA's as Intermediates and Products in the Splicing of Messenger RNA precursors

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3902173

Excision of an intact intron as a novel lariat structure during pre-mRNA splicing in vitro

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3902173

Electrophoretic separation of complexes involved in the splicing of precursors to mRNAs

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3902173

Ser/Thr-specific protein phosphatases are required for both catalytic steps of pre-mRNA splicing

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3902173

Identification and H2O2 sensitivity of the major constitutive MAPK phosphatase from rat brain

7 July 2018

1 reference

Crossref

https://api.crossref.org/works/10.1177%2F1087057113493117

Specific small nuclear RNAs are associated with yeast spliceosomes

21 January 2018

1 reference

12 December 2020

Naphthazarin derivatives: synthesis, cytotoxic mechanism and evaluation of antitumor activity

1 reference

12 December 2020

PP1/PP2A phosphatases are required for the second step of Pre-mRNA splicing and target specific snRNP proteins

1 reference

12 December 2020

Tetrocarcin-A--induced ER stress mediates apoptosis in B-CLL cells via a Bcl-2--independent pathway

1 reference

12 December 2020

Tetrocarcin A inhibits mitochondrial functions of Bcl-2 and suppresses its anti-apoptotic activity

1 reference

12 December 2020

Novel antitumor antibiotics, tetrocarcins

1 reference

12 December 2020

The role of the mammalian branchpoint sequence in pre-mRNA splicing

1 reference

12 December 2020

New antitumor substances, FR901463, FR901464 and FR901465. II. Activities against experimental tumors in mice and mechanism of action

1 reference

12 December 2020

Identifiers

DOI

10.1177/1087057113493117

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23771823%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23771823%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

PubMed publication ID

23771823

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23771823%20AND%20SRC:MED&resulttype=core&format=json