(Q34776150)

4 August 2017

title

Regorafenib (BAY 73-4506): antitumor and antimetastatic activities in preclinical models of colorectal cancer (English)

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4 August 2017

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Roberta Schmieder

1

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4 August 2017

Jens Hoffmann

2

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4 August 2017

Michael Becker

3

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4 August 2017

Ajay Bhargava

4

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4 August 2017

Tina Müller

5

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4 August 2017

Nicole Kahmann

6

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4 August 2017

Peter Ellinghaus

7

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4 August 2017

Robert Adams

8

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4 August 2017

André Rosenthal

9

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4 August 2017

Karl-Heinz Thierauch

10

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4 August 2017

Arne Scholz

11

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4 August 2017

Scott M Wilhelm

12

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4 August 2017

Dieter Zopf

13

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4 August 2017

language of work or name

English

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publication date

17 April 2014

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International Journal of Cancer

4 August 2017

published in

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4 August 2017

volume

135

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4 August 2017

issue

6

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4 August 2017

page(s)

1487-1496

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Regorafenib inhibits growth, angiogenesis, and metastasis in a highly aggressive, orthotopic colon cancer model

4 August 2017

cites work

1 reference

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Regorafenib in combination with FOLFOX or FOLFIRI as first- or second-line treatment of colorectal cancer: results of a multicenter, phase Ib study

7 July 2018

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Rapid decrease in tumor perfusion following VEGF blockade predicts long-term tumor growth inhibition in preclinical tumor models

7 July 2018

1 reference

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Regorafenib monotherapy for previously treated metastatic colorectal cancer (CORRECT): an international, multicentre, randomised, placebo-controlled, phase 3 trial

7 July 2018

1 reference

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Cancer treatment and survivorship statistics, 2012

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4277327

Prognostic and predictive biomarkers for epidermal growth factor receptor-targeted therapy in colorectal cancer: beyond KRAS mutations

7 July 2018

1 reference

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Molecular link mechanisms between inflammation and cancer

7 July 2018

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Beyond bevacizumab: new anti-VEGF strategies in colorectal cancer

7 July 2018

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Regorafenib (BAY 73-4506) in advanced colorectal cancer: a phase I study

7 July 2018

1 reference

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Therapeutic strategy in unresectable metastatic colorectal cancer.

7 July 2018

1 reference

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7 July 2018

Cancer statistics, 2012

1 reference

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7 July 2018

Global cancer statistics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4277327

Regorafenib (BAY 73-4506): a new oral multikinase inhibitor of angiogenic, stromal and oncogenic receptor tyrosine kinases with potent preclinical antitumor activity

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4277327

Global patterns of cancer incidence and mortality rates and trends

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4277327

Phase II trial of infusional fluorouracil, irinotecan, and bevacizumab for metastatic colorectal cancer: efficacy and circulating angiogenic biomarkers associated with therapeutic resistance

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4277327

Worldwide variations in colorectal cancer

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4277327

Chemotherapy, bevacizumab, and cetuximab in metastatic colorectal cancer

7 July 2018

1 reference

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IQGAP1-dependent signaling pathway regulates endothelial cell proliferation and angiogenesis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4277327

Blocking VEGFR-3 suppresses angiogenic sprouting and vascular network formation

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4277327

Antiangiogenic and anticolorectal cancer effects of metronomic irinotecan chemotherapy alone and in combination with semaxinib

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4277327

ZD1839 induces p15INK4b and causes G1 arrest by inhibiting the mitogen-activated protein kinase/extracellular signal-regulated kinase pathway

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4277327

BAY 43-9006 exhibits broad spectrum oral antitumor activity and targets the RAF/MEK/ERK pathway and receptor tyrosine kinases involved in tumor progression and angiogenesis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4277327

Colorectal metastasis (liver and lung).

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4277327

Suppression of tumor lymphangiogenesis and lymph node metastasis by blocking vascular endothelial growth factor receptor 3 signaling.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4277327

Short tandem repeat profiling provides an international reference standard for human cell lines

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4277327

Vascular endothelial growth factor-C-mediated lymphangiogenesis promotes tumour metastasis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4277327

Expression of vascular endothelial growth factor and its receptor, KDR, correlates with vascularity, metastasis, and proliferation of human colon cancer

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4277327

Regulation by vascular endothelial growth factor of human colon cancer tumorigenesis in a mouse model of experimental liver metastasis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4277327

A genetic model for colorectal tumorigenesis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4277327

Tumor induction relationships in development of transplantable cancers of the colon in mice for chemotherapy assays, with a note on carcinogen structure

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4277327

International trends in colorectal cancer incidence rates

7 July 2018

1 reference

Anticancer drug response and expression of molecular markers in early-passage xenotransplanted colon carcinomas.

21 January 2018

1 reference

Activation and antitumor activity of CPT-11 in plasma esterase-deficient mice

21 January 2018

1 reference

Effect of vascular normalization by antiangiogenic therapy on interstitial hypertension, peritumor edema, and lymphatic metastasis: insights from a mathematical model

21 January 2018

1 reference

Mucinous histology predicts for reduced fluorouracil responsiveness and survival in advanced colorectal cancer

21 January 2018

1 reference

Vessel counts and expression of vascular endothelial growth factor as prognostic factors in node-negative colon cancer

21 January 2018

1 reference

12 December 2020

Biology of colorectal cancer

1 reference

12 December 2020

Vascular endothelial growth factor is an in vivo survival factor for tumor endothelium in a murine model of colorectal carcinoma liver metastases

1 reference

12 December 2020

Epidermal growth factor receptor immunohistochemical reactivity in patients with American Joint Committee on Cancer Stage IV colon adenocarcinoma: implications for a standardized scoring system

1 reference

12 December 2020

Advanced colorectal cancer: ESMO Clinical Practice Guidelines for treatment

1 reference

12 December 2020

A multicenter, phase II trial of weekly irinotecan (CPT-11) in patients with previously treated colorectal carcinoma

1 reference

12 December 2020

Identifiers

DOI

10.1002/IJC.28669

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4 August 2017

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4 August 2017

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