(Q33388951)

26 July 2017

title

IQGAP1-dependent signaling pathway regulates endothelial cell proliferation and angiogenesis (English)

1 reference

26 July 2017

0 references

1 reference

Nader Rahimi

3

0 references

David B. Sacks

object named as

David B Sacks

series ordinal

2

0 references

author name string

Rosana D Meyer

series ordinal

1

1 reference

26 July 2017

language of work or name

English

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publication date

3 December 2008

1 reference

26 July 2017

1 reference

26 July 2017

volume

3

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26 July 2017

issue

12

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26 July 2017

page(s)

e3848

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Creative Commons Attribution 4.0 International

26 July 2017

copyright license

start time

3 December 2008

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

IQGAP1 modulates activation of B-Raf

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2585478

A critical role for the E3-ligase activity of c-Cbl in VEGFR-2-mediated PLCgamma1 activation and angiogenesis

21 June 2018

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Identification and functional characterization of an Src homology domain 3 domain-binding site on Cbl

21 June 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2585478

VEGF receptor signalling - in control of vascular function

21 June 2018

1 reference

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Angiogenesis in life, disease and medicine

21 June 2018

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VEGFR-1 and VEGFR-2: two non-identical twins with a unique physiognomy

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2585478

The carboxyl terminus of VEGFR-2 is required for PKC-mediated down-regulation

21 June 2018

1 reference

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Essential role of Flk-1 (VEGF receptor 2) tyrosine residue 1173 in vasculogenesis in mice

21 June 2018

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Regulation of protein kinases; controlling activity through activation segment conformation

21 June 2018

1 reference

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Substitution of C-terminus of VEGFR-2 with VEGFR-1 promotes VEGFR-1 activation and endothelial cell proliferation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2585478

The adaptor protein shb binds to tyrosine 1175 in vascular endothelial growth factor (VEGF) receptor-2 and regulates VEGF-dependent cellular migration

21 June 2018

1 reference

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IQGAP1 binds ERK2 and modulates its activity

21 June 2018

1 reference

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Src family kinases in tumor progression and metastasis

21 June 2018

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IQGAP proteins are integral components of cytoskeletal regulation

21 June 2018

1 reference

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Src promotes destruction of c-Cbl: implications for oncogenic synergy between Src and growth factor receptors

21 June 2018

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Recruitment and activation of phospholipase Cgamma1 by vascular endothelial growth factor receptor-2 are required for tubulogenesis and differentiation of endothelial cells

21 June 2018

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Sck is expressed in endothelial cells and participates in vascular endothelial growth factor-induced signaling

21 June 2018

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Tyrosine residues 951 and 1059 of vascular endothelial growth factor receptor-2 (KDR) are essential for vascular permeability factor/vascular endothelial growth factor-induced endothelium migration and proliferation, respectively

21 June 2018

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A single autophosphorylation site on KDR/Flk-1 is essential for VEGF-A-dependent activation of PLC-gamma and DNA synthesis in vascular endothelial cells

21 June 2018

1 reference

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Identification of tyrosine residues in vascular endothelial growth factor receptor-2/FLK-1 involved in activation of phosphatidylinositol 3-kinase and cell proliferation

21 June 2018

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21 June 2018

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2585478

21 June 2018

https://pubmed.ncbi.nlm.nih.gov/19050761

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

VEGF activates protein kinase C-dependent, but Ras-independent Raf-MEK-MAP kinase pathway for DNA synthesis in primary endothelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2585478

Src family kinases are required for integrin but not PDGFR signal transduction.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2585478

Sck interacts with KDR and Flt-1 via its SH2 domain

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2585478

c-Cbl is downstream of c-Src in a signalling pathway necessary for bone resorption.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2585478

Failure of blood-island formation and vasculogenesis in Flk-1-deficient mice

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2585478

SH2 domain specificity and activity modified by a single residue

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2585478

A mechanosensory complex that mediates the endothelial cell response to fluid shear stress

21 June 2018

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https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0003848

The presence of a single tyrosine residue at the carboxyl domain of vascular endothelial growth factor receptor-2/FLK-1 regulates its autophosphorylation and activation of signaling molecules

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0003848

Selective requirement for Src kinases during VEGF-induced angiogenesis and vascular permeability

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0003848

IQGAP1, a novel vascular endothelial growth factor receptor binding protein, is involved in reactive oxygen species--dependent endothelial migration and proliferation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0003848

Role of Raf in vascular protection from distinct apoptotic stimuli

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19050761

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Receptor chimeras indicate that the vascular endothelial growth factor receptor-1 (VEGFR-1) modulates mitogenic activity of VEGFR-2 in endothelial cells

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19050761

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1371/JOURNAL.PONE.0003848

1 reference

26 July 2017

0 references

1 reference

26 July 2017

1 reference