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IQGAP1 modulates activation of B-Raf
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scholarly article
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title
IQGAP1 modulates activation of B-Raf
(English)
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main subject
B-Raf proto-oncogene, serine/threonine kinase
1 reference
stated in
GOA release 2020-03-11
IQ motif containing GTPase activating protein 1
1 reference
stated in
GOA release 2020-03-11
cellular response to epidermal growth factor stimulus
1 reference
stated in
GOA release 2020-03-11
IQ motif containing GTPase activating protein 1
1 reference
stated in
GOA release 2020-03-11
Braf transforming gene
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stated in
GOA release 2020-03-11
author name string
Jian-Guo Ren
series ordinal
1
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Zhigang Li
series ordinal
2
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David B Sacks
series ordinal
3
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language of work or name
English
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publication date
19 June 2007
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published in
Proceedings of the National Academy of Sciences of the United States of America
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volume
104
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page(s)
10465-9
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issue
25
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cites work
IQGAP proteins are integral components of cytoskeletal regulation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1965536
retrieved
19 March 2017
A proteomics strategy to elucidate functional protein-protein interactions applied to EGF signaling
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1965536
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19 March 2017
Gastric hyperplasia in mice lacking the putative Cdc42 effector IQGAP1
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1965536
retrieved
19 March 2017
IQGAP1, a calmodulin-binding protein with a rasGAP-related domain, is a potential effector for cdc42Hs
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1965536
retrieved
19 March 2017
Structure and biological activity of v-raf, a unique oncogene transduced by a retrovirus
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1965536
retrieved
19 March 2017
Mutations of the BRAF gene in human cancer
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1965536
retrieved
19 March 2017
IQGAP1: a key regulator of adhesion and migration
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1965536
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19 March 2017
B-Raf and Raf-1 are regulated by distinct autoregulatory mechanisms
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1965536
retrieved
19 March 2017
Interaction with IQGAP1 links APC to Rac1, Cdc42, and actin filaments during cell polarization and migration
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1965536
retrieved
19 March 2017
Mechanism of activation of the RAF-ERK signaling pathway by oncogenic mutations of B-RAF
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1965536
retrieved
19 March 2017
IQGAP1 binds ERK2 and modulates its activity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1965536
retrieved
19 March 2017
Mechanisms of regulating the Raf kinase family
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1965536
retrieved
19 March 2017
Rac1 and Cdc42 capture microtubules through IQGAP1 and CLIP-170
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1965536
retrieved
19 March 2017
IQGAP1 is a component of Cdc42 signaling to the cytoskeleton
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1965536
retrieved
19 March 2017
The mechanism for regulation of the F-actin binding activity of IQGAP1 by calcium/calmodulin
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1965536
retrieved
19 March 2017
IQGAP1-mediated stimulation of transcriptional co-activation by beta-catenin is modulated by calmodulin
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1965536
retrieved
19 March 2017
Genomic analysis of metastasis reveals an essential role for RhoC
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1965536
retrieved
19 March 2017
IQGAP1 and calmodulin modulate E-cadherin function
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1965536
retrieved
19 March 2017
Role of IQGAP1, a target of the small GTPases Cdc42 and Rac1, in regulation of E-cadherin- mediated cell-cell adhesion
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1965536
retrieved
19 March 2017
Regulation of cross-linking of actin filament by IQGAP1, a target for Cdc42
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1965536
retrieved
19 March 2017
Calmodulin modulates the interaction between IQGAP1 and Cdc42. Identification of IQGAP1 by nanoelectrospray tandem mass spectrometry
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1965536
retrieved
19 March 2017
The complexity of Raf-1 regulation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1965536
retrieved
19 March 2017
Identification of a putative effector for Cdc42Hs with high sequence similarity to the RasGAP-related protein IQGAP1 and a Cdc42Hs binding partner with similarity to IQGAP2
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1965536
retrieved
19 March 2017
Modulation of kinase activity and oncogenic properties by alternative splicing reveals a novel regulatory mechanism for B-Raf
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1965536
retrieved
19 March 2017
Mitogen-activated protein (MAP) kinase pathways: regulation and physiological functions
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stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1965536
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7 April 2017
Coordinating ERK/MAPK signalling through scaffolds and inhibitors
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1965536
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7 April 2017
The RAF proteins take centre stage
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1965536
retrieved
7 April 2017
ERK and p38 MAPK-activated protein kinases: a family of protein kinases with diverse biological functions
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1965536
retrieved
7 April 2017
Regulation of MAP Kinase Signaling Modules by Scaffold Proteins in Mammals
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stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1965536
retrieved
7 April 2017
IQGAP1 in cellular signaling: bridging the GAP.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1965536
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27 September 2017
Self-association of IQGAP1: characterization and functional sequelae
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1965536
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27 September 2017
The transcriptional activity of estrogen receptor-alpha is dependent on Ca2+/calmodulin.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1965536
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27 September 2017
Propagation and maintenance of undifferentiated human embryonic stem cells
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stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1965536
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27 September 2017
The molecular scaffold KSR1 regulates the proliferative and oncogenic potential of cells
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1965536
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27 September 2017
IQGAPs: integrators of the cytoskeleton, cell adhesion machinery, and signaling networks
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1965536
retrieved
27 September 2017
IQGAP1 as signal integrator: Ca2+, calmodulin, Cdc42 and the cytoskeleton
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1965536
retrieved
27 September 2017
Activation of B-Raf kinase requires phosphorylation of the conserved residues Thr598 and Ser601.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1965536
retrieved
27 September 2017
Abrogation of simian virus 40 DNA-mediated transformation of primary C57BL/6 mouse embryo fibroblasts by exposure to a simian virus 40-specific cytotoxic T-lymphocyte clone
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1965536
retrieved
27 September 2017
IQGAP1 promotes cell motility and invasion
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1965536
retrieved
30 May 2018
Identification of an actin cytoskeletal complex that includes IQGAP and the Cdc42 GTPase
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/17563371
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
IQGAP1 integrates Ca2+/calmodulin and Cdc42 signaling
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/17563371
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1073/PNAS.0611308104
0 references
ADS bibcode
2007PNAS..10410465R
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PMCID
1965536
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PubMed ID
17563371
0 references
ResearchGate publication ID
6274379
0 references
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