(Q34785084)

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mGluR5 positive allosteric modulation and its effects on MK-801 induced set-shifting impairments in a rat operant delayed matching/non-matching-to-sample task

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scholarly article

1 reference

Europe PubMed Central

4 August 2017

mGluR5 positive allosteric modulation and its effects on MK-801 induced set-shifting impairments in a rat operant delayed matching/non-matching-to-sample task (English)

1 reference

Europe PubMed Central

4 August 2017

M. Foster Olive

9

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24973895%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

author name string

Amber L LaCrosse

1

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10 June 2020

Brian T Burrows

2

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10 June 2020

Rachel M Angulo

3

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10 June 2020

Phoebe R Conrad

4

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10 June 2020

Sarah M Himes

5

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10 June 2020

Nordia Mathews

6

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10 June 2020

Scott A Wegner

7

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10 June 2020

Sara B Taylor

8

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10 June 2020

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publication date

29 June 2014

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4 August 2017

Psychopharmacology

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10 June 2020

232

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10 June 2020

1

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10 June 2020

251-258

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10 June 2020

https://scigraph.springernature.com/pub.10.1007/s00213-014-3653-8

0 references

NMDA hypofunction as a convergence point for progression and symptoms of schizophrenia

1 reference

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7 July 2018

Allosteric modulators for the treatment of schizophrenia: targeting glutamatergic networks

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7 July 2018

Translational Concepts of mGluR5 in Synaptic Diseases of the Brain

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7 July 2018

Glycine transport inhibitors in the treatment of schizophrenia

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7 July 2018

In vitro characterisation of the novel positive allosteric modulators of the mGlu₅ receptor, LSN2463359 and LSN2814617, and their effects on sleep architecture and operant responding in the rat.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4278949

7 July 2018

Animal models of working memory: a review of tasks that might be used in screening drug treatments for the memory impairments found in schizophrenia.

1 reference

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7 July 2018

Selective remediation of reversal learning deficits in the neurodevelopmental MAM model of schizophrenia by a novel mGlu5 positive allosteric modulator

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7 July 2018

Loss of object recognition memory produced by extended access to methamphetamine self-administration is reversed by positive allosteric modulation of metabotropic glutamate receptor 5

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7 July 2018

Functional interaction of mGlu5 and NMDA receptors in aversive learning in rats.

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7 July 2018

Potential psychiatric applications of metabotropic glutamate receptor agonists and antagonists

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7 July 2018

Activation of type 5 metabotropic glutamate receptors attenuates deficits in cognitive flexibility induced by NMDA receptor blockade

1 reference

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7 July 2018

Group 5 metabotropic glutamate receptors: role in modulating cortical activity and relevance to cognition

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7 July 2018

Metabotropic glutamate receptors: physiology, pharmacology, and disease

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7 July 2018

mGluR5 positive allosteric modulators facilitate both hippocampal LTP and LTD and enhance spatial learning

1 reference

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7 July 2018

Orbitofrontal cortex neurons as a common target for classic and glutamatergic antipsychotic drugs

1 reference

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7 July 2018

Interaction of N-methyl-D-aspartate and group 5 metabotropic glutamate receptors on behavioral flexibility using a novel operant set-shift paradigm

1 reference

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7 July 2018

Positive allosteric modulation of metabotropic glutamate 5 (mGlu5) receptors reverses N-Methyl-D-aspartate antagonist-induced alteration of neuronal firing in prefrontal cortex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4278949

7 July 2018

Metabotropic glutamate receptors: intracellular signaling pathways.

1 reference

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7 July 2018

NMDA receptor antagonism impairs reversal learning in developing rats

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4278949

7 July 2018

Predicting drug efficacy for cognitive deficits in schizophrenia

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7 July 2018

Allosteric potentiators of metabotropic glutamate receptor subtype 5 have differential effects on different signaling pathways in cortical astrocytes

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7 July 2018

A novel selective positive allosteric modulator of metabotropic glutamate receptor subtype 5 has in vivo activity and antipsychotic-like effects in rat behavioral models

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7 July 2018

An overview of the tasks used to test working memory in rodents

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7 July 2018

Longitudinal studies of cognition and functional outcome in schizophrenia: implications for MATRICS.

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7 July 2018

Spatial memory, recognition memory, and the hippocampus

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7 July 2018

Effects of antipsychotic drugs on operant responding after acute and repeated administration

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7 July 2018

Structural, signalling and regulatory properties of the group I metabotropic glutamate receptors: prototypic family C G-protein-coupled receptors

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7 July 2018

Activation of synaptic NMDA receptors induces membrane insertion of new AMPA receptors and LTP in cultured hippocampal neurons

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7 July 2018

Current and novel approaches to the drug treatment of schizophrenia

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7 July 2018

NMDA receptor hypofunction model of schizophrenia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4278949

7 July 2018

Learning impairments induced by glutamate blockade using dizocilpine (MK-801) in monkeys.

1 reference

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7 July 2018

The non-competitive NMDA antagonist MK-801 increases food intake in rats.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4278949

7 July 2018

Selective alterations in gene expression for NMDA receptor subunits in prefrontal cortex of schizophrenics

1 reference

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7 July 2018

Further evidence for dementia of the prefrontal type in schizophrenia? A controlled study of teaching the Wisconsin Card Sorting Test.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4278949

7 July 2018

Behavioral effects of MK-801 in the rat.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4278949

7 July 2018

The generalized pattern of neuropsychological deficits in outpatients with chronic schizophrenia with heterogeneous Wisconsin Card Sorting Test results

1 reference

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7 July 2018

Allosteric enhancement of metabotropic glutamate receptor 5 function promotes spatial memory.

1 reference

https://api.crossref.org/works/10.1007%2FS00213-014-3653-8

21 January 2018

Enhancement of social novelty discrimination by positive allosteric modulators at metabotropic glutamate 5 receptors: adolescent administration prevents adult-onset deficits induced by neonatal treatment with phencyclidine.

1 reference

https://api.crossref.org/works/10.1007%2FS00213-014-3653-8

21 January 2018

Impairment in perceptual attentional set-shifting following PCP administration: a rodent model of set-shifting deficits in schizophrenia

1 reference

https://api.crossref.org/works/10.1007%2FS00213-014-3653-8

21 January 2018

Effects of a metabotropic glutamate receptor 5 positive allosteric modulator, CDPPB, on spatial learning task performance in rodents.

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21 January 2018

The mGlu₅ positive allosteric modulator LSN2463359 differentially modulates motor, instrumental and cognitive effects of NMDA receptor antagonists in the rat.

1 reference

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21 January 2018

NMDA channels control meal size via central vagal afferent terminals

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21 January 2018

Therapeutic effects of metabotropic glutamate receptor 5 positive allosteric modulator CDPPB on phencyclidine-induced cognitive deficits in mice.

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21 January 2018

Electrolytic lesions of the medial prefrontal cortex in rats disrupt performance on an analog of the Wisconsin Card Sorting Test, but do not disrupt latent inhibition: implications for animal models of schizophrenia.

1 reference

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21 January 2018

Persisting cognitive deficits induced by low-dose, subchronic treatment with MK-801 in adolescent rats.

1 reference

https://api.crossref.org/works/10.1007%2FS00213-014-3653-8

21 January 2018

Glutamate signaling in the pathophysiology and therapy of schizophrenia

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21 January 2018

The influence of NMDA receptors in the dorsomedial striatum on response reversal learning

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21 January 2018

Mechanism based neurotoxicity of mGlu5 positive allosteric modulators--development challenges for a promising novel antipsychotic target

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21 January 2018

Working memory deficit as a core neuropsychological dysfunction in schizophrenia.

1 reference

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21 January 2018

Lesions of the dorsal vagal complex abolish increases in meal size induced by NMDA receptor blockade

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21 January 2018

Dose-dependent effect of CDPPB, the mGluR5 positive allosteric modulator, on recognition memory is associated with GluR1 and CREB phosphorylation in the prefrontal cortex and hippocampus.

1 reference

https://api.crossref.org/works/10.1007%2FS00213-014-3653-8

21 January 2018

The difference in effect of mGlu2/3 and mGlu5 receptor agonists on cognitive impairment induced by MK-801.

1 reference

https://api.crossref.org/works/10.1007%2FS00213-014-3653-8

21 January 2018

The NMDA-receptor antagonist MK-801 selectively disrupts reversal learning in rats

1 reference

https://api.crossref.org/works/10.1007%2FS00213-014-3653-8

21 January 2018

Effects of the cognition impairer MK-801 on learning and memory in mice and rats.

1 reference

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21 January 2018

Glycine transport inhibitors as potential antipsychotic drugs.

1 reference

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21 January 2018

MK-801 produces a deficit in sucrose preference that is reversed by clozapine, D-serine, and the metabotropic glutamate 5 receptor positive allosteric modulator CDPPB: relevance to negative symptoms associated with schizophrenia?

1 reference

https://api.crossref.org/works/10.1007%2FS00213-014-3653-8

21 January 2018

The effect of dizocilpine (MK-801) on spatial and visual discrimination tasks in the rat.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4278949

26 October 2018

Kinetics of MK-801 and its effect on quinolinic acid-induced seizures and neurotoxicity in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/24973895

12 December 2020

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Wisconsin Card Sorting Test: an indicator of vulnerability to schizophrenia?

1 reference

https://pubmed.ncbi.nlm.nih.gov/24973895

12 December 2020

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10.1007/S00213-014-3653-8

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Europe PubMed Central

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10 June 2020

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24 November 2022

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Europe PubMed Central

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10 June 2020

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Europe PubMed Central

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10 June 2020

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