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Translational Concepts of mGluR5 in Synaptic Diseases of the Brain
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19 February 2020
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title
Translational Concepts of mGluR5 in Synaptic Diseases of the Brain
(English)
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19 February 2020
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Thomas M Piers
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1
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19 February 2020
Philip Regan
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4
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19 February 2020
Daniel J. Whitcomb
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5
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19 February 2020
Kwangwook Cho
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19 February 2020
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Dong Hyun Kim
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19 February 2020
Byeong C Kim
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3
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19 February 2020
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27 November 2012
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19 February 2020
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Frontiers in Pharmacology
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19 February 2020
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3
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19 February 2020
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199
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19 February 2020
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A promoter variant of SHANK1 affects auditory working memory in schizophrenia patients and in subjects clinically at risk for psychosis
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Therapeutic significance of NR2B-containing NMDA receptors and mGluR5 metabotropic glutamate receptors in mediating the synaptotoxic effects of β-amyloid oligomers on long-term potentiation (LTP) in murine hippocampal slices.
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21 September 2018
MK-801 produces a deficit in sucrose preference that is reversed by clozapine, D-serine, and the metabotropic glutamate 5 receptor positive allosteric modulator CDPPB: relevance to negative symptoms associated with schizophrenia?
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Group I metabotropic glutamate receptors control proliferation, survival and differentiation of cultured neural progenitor cells isolated from the subventricular zone of adult mice.
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21 September 2018
Clozapine reverses schizophrenia-related behaviours in the metabotropic glutamate receptor 5 knockout mouse: association with N-methyl-D-aspartic acid receptor up-regulation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3506921
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21 September 2018
Homer interactions are necessary for metabotropic glutamate receptor-induced long-term depression and translational activation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3506921
retrieved
21 September 2018
Nicotinic receptor-mediated enhancement of long-term potentiation involves activation of metabotropic glutamate receptors and ryanodine-sensitive calcium stores in the dentate gyrus
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3506921
retrieved
21 September 2018
Experience-dependent modification of mechanisms of long-term depression.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3506921
retrieved
21 September 2018
A reduced number of metabotropic glutamate subtype 5 receptors are associated with constitutive homer proteins in a mouse model of fragile X syndrome.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3506921
retrieved
21 September 2018
Suppression of two major Fragile X Syndrome mouse model phenotypes by the mGluR5 antagonist MPEP.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3506921
retrieved
21 September 2018
Endogenous activation of metabotropic glutamate receptors supports the proliferation and survival of neural progenitor cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3506921
retrieved
21 September 2018
Key role of the postsynaptic density scaffold proteins Shank and Homer in the functional architecture of Ca2+ homeostasis at dendritic spines in hippocampal neurons.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3506921
retrieved
21 September 2018
The mGlu5 metabotropic glutamate receptor is expressed in zones of active neurogenesis of the embryonic and postnatal brain
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3506921
retrieved
21 September 2018
Functional Interaction Between NMDA and mGlu5 Receptors: Effects on Working Memory, Instrumental Learning, Motor Behaviors, and Dopamine Release
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3506921
retrieved
21 September 2018
Aberrant expression of metabotropic glutamate receptor 2 in the vulnerable neurons of Alzheimer's disease
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3506921
retrieved
21 September 2018
Determination of group I metabotropic glutamate receptor subtypes involved in the frequency of epileptiform activity in vitro using mGluR1 and mGluR5 mutant mice
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3506921
retrieved
21 September 2018
Differential distribution of group I metabotropic glutamate receptors during rat cortical development
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3506921
retrieved
21 September 2018
Immunohistochemical localization of group I and II metabotropic glutamate receptors in control and amyotrophic lateral sclerosis human spinal cord: upregulation in reactive astrocytes.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3506921
retrieved
21 September 2018
Enhanced early developmental expression of the metabotropic glutamate receptor mGluR5 in rat brain: protein, mRNA splice variants, and regional distribution
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3506921
retrieved
21 September 2018
Characterisation of LTP induced by the activation of glutamate metabotropic receptors in area CA1 of the hippocampus
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3506921
retrieved
21 September 2018
Metabotropic glutamate receptors: electrophysiological properties and role in plasticity
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/23205012
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Metabotropic glutamate receptors are differentially regulated during development
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/23205012
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Block of long-term potentiation by naturally secreted and synthetic amyloid beta-peptide in hippocampal slices is mediated via activation of the kinases c-Jun N-terminal kinase, cyclin-dependent kinase 5, and p38 mitogen-activated protein kinase as
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/23205012
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Expression of metabotropic glutamate receptor subtype mRNA (mGluR1-8) in human cerebellum
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/23205012
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.3389/FPHAR.2012.00199
1 reference
stated in
Europe PubMed Central
PMC publication ID
3506921
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23205012%20AND%20SRC:MED&resulttype=core&format=json
retrieved
19 February 2020
Fatcat ID
release_lp765vmxdzaopjk7tlgewsneli
1 reference
stated in
Fatcat
reference URL
https://api.fatcat.wiki/v0/release/lp765vmxdzaopjk7tlgewsneli
retrieved
24 November 2022
based on heuristic
mapped directly with Wikidata item
PMC publication ID
3506921
1 reference
stated in
Europe PubMed Central
PMC publication ID
3506921
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23205012%20AND%20SRC:MED&resulttype=core&format=json
retrieved
19 February 2020
PubMed publication ID
23205012
1 reference
stated in
Europe PubMed Central
PMC publication ID
3506921
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23205012%20AND%20SRC:MED&resulttype=core&format=json
retrieved
19 February 2020
ResearchGate publication ID
233830929
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