(Q34785439)

4 August 2017

1 reference

8 February 2021

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systematic review

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title

The Prognostic Value of p16 Hypermethylation in Cancer: A Meta-Analysis (English)

1 reference

cyclin dependent kinase inhibitor 2A

4 August 2017

main subject

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10 December 2019

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4 September 2020

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20 October 2020

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8 February 2021

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inferred from abstract

non-small-cell lung carcinoma

1 reference

inferred from abstract

1 reference

Xiang-Bin Xing

1

1 reference

4 August 2017

Wei-Bin Cai

2

1 reference

4 August 2017

Liang Luo

3

1 reference

4 August 2017

Long-Shan Liu

4

1 reference

4 August 2017

Hui-Juan Shi

5

1 reference

4 August 2017

Min-Hu Chen

6

1 reference

4 August 2017

language of work or name

English

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publication date

21 June 2013

9 references

4 August 2017

3 April 2019

2 August 2019

20 November 2019

10 December 2019

18 December 2019

4 September 2020

20 October 2020

8 February 2021

9 references

4 August 2017

3 April 2019

2 August 2019

20 November 2019

10 December 2019

18 December 2019

4 September 2020

20 October 2020

8 February 2021

8

1 reference

4 August 2017

issue

6

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4 August 2017

page(s)

e66587

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Creative Commons Attribution 4.0 International

4 August 2017

copyright license

8 references

3 April 2019

2 August 2019

20 November 2019

10 December 2019

18 December 2019

4 September 2020

20 October 2020

on focus list of Wikimedia project

8 February 2021

copyright status

copyrighted

0 references

ScienceSource

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cites work

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7 July 2018

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Significant impact of promoter hypermethylation and the 540 C>T polymorphism of CDKN2A in cutaneous melanoma of the vertical growth phase

7 July 2018

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Role of p53 as a prognostic factor for survival in lung cancer: a systematic review of the literature with a meta-analysis

7 July 2018

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Extracting summary statistics to perform meta-analyses of the published literature for survival endpoints

7 July 2018

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7 July 2018

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A new regulatory motif in cell-cycle control causing specific inhibition of cyclin D/CDK4

7 July 2018

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Beta blockade during and after myocardial infarction: an overview of the randomized trials

7 July 2018

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7 July 2018

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Hypermethylator phenotype in sporadic colon cancer: study on a population-based series of 582 cases

21 January 2018

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Influence of methylated p15 and p16 genes on clinicopathological features in colorectal cancer.

21 January 2018

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Adverse Prognostic Effect of Methylation in Colorectal Cancer Is Reversed by Microsatellite Instability

21 January 2018

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The methylation status and protein expression of CDH1, p16(INK4A), and fragile histidine triad in nonsmall cell lung carcinoma: epigenetic silencing, clinical features, and prognostic significance

21 January 2018

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Loss of function of p16 gene and prognosis of pulmonary adenocarcinoma.

21 January 2018

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p16INK4A hypermethylation is associated with hepatitis virus infection, age, and gender in hepatocellular carcinoma.

21 January 2018

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CpG island methylator phenotype associated with tumor recurrence in tumor-node-metastasis stage I hepatocellular carcinoma.

21 January 2018

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Aberrant methylation of p16 predicts candidates for 5-fluorouracil-based adjuvant therapy in gastric cancer patients

21 January 2018

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Differential roles of p16INK4A and p14ARF genes in prognosis of oral carcinoma.

21 January 2018

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p16(INK4A) promoter hypermethylation is associated with invasiveness and prognosis of oral squamous cell carcinoma in an age-dependent manner

21 January 2018

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p16INK4a and p14ARF methylation as a potential biomarker for human bladder cancer.

21 January 2018

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An integrated analysis of germline and somatic, genetic and epigenetic alterations at 9p21.3 in glioblastoma

21 January 2018

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21 January 2018

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Hypermethylation of the thrombospondin-1 gene is associated with poor prognosis in penile squamous cell carcinoma.

21 January 2018

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p16 gene methylation in colorectal cancer patients with long-term follow-up.

21 January 2018

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Prognostic relevance of promoter hypermethylation of multiple genes in breast cancer patients.

26 October 2018

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Prostaglandin E2 receptor 2 overexpression in squamous cell carcinoma of the lung correlates with p16INK4A methylation and an unfavorable prognosis.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3689792

Hypermethylation of the CDKN2A gene in colorectal cancer is associated with shorter survival.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3689792

K-ras and p16 aberrations confer poor prognosis in human colorectal cancer

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3689792

Hypermethylation of the p16 Gene in Sporadic T3N0M0 Stage Colorectal Cancers: Association with DNA Replication Error and Shorter Survival

26 October 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0066587

Inactivation of p16 by CpG hypermethylation in renal cell carcinoma

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3689792

Aberrant promoter methylation profile and association with survival in patients with non-small cell lung cancer

9 December 2018

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12 December 2020

Promoter hypermethylation of RASSF1A and RUNX3 genes as an independent prognostic prediction marker in surgically resected non-small cell lung cancers

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12 December 2020

PTEN, RASSF1 and DAPK site-specific hypermethylation and outcome in surgically treated stage I and II nonsmall cell lung cancer patients

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12 December 2020

Promoter methylation of specific genes is associated with the phenotype and progression of colorectal adenocarcinomas

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12 December 2020

Hypermethylation of p16(INK4a) and p15(INK4b) genes in non-small cell lung cancer

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12 December 2020

Methylation of tumor suppressor gene p16 and prognosis of epithelial ovarian cancer

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12 December 2020

Alterations of the p16(ink4a) gene in resected nonsmall cell lung tumors and exfoliated cells within sputum

1 reference

12 December 2020

1 reference

12 December 2020

Differential impact of p16 inactivation by promoter methylation in non-small cell lung and colorectal cancer: clinical implications

1 reference

12 December 2020

Promoter hypermethylation of the p16 and Wif-1 genes as an independent prognostic marker in stage IA non-small cell lung cancers

1 reference

12 December 2020

Molecular characterization of chronic obstructive pulmonary disease-related non-small cell lung cancer through aberrant methylation and alterations of EGFR signaling

1 reference

12 December 2020

The correlations between alteration of p16 gene and clinicopathological factors and prognosis in squamous cell carcinomas of the buccal mucosa

1 reference

12 December 2020

Molecular and Immunohistochemical Analysis of the Prognostic Value of Cell-Cycle Regulators in Urothelial Neoplasms of the Bladder

1 reference

12 December 2020

Mechanisms of inactivation of the p16INK4a gene in leiomyosarcoma of soft tissue: decreased p16 expression correlates with promoter methylation and poor prognosis

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12 December 2020

Aberrant p16((INK4a)) methylation is a frequent event in colorectal cancers: prognostic value and relation to mRNA expression and immunoreactivity

1 reference

12 December 2020

10.1371/JOURNAL.PONE.0066587

Identifiers

DOI

1 reference

4 August 2017

0 references

1 reference

4 August 2017

1 reference