(Q34790159)

4 August 2017

title

Evidence that cathelicidin peptide LL-37 may act as a functional ligand for CXCR2 on human neutrophils (English)

1 reference

4 August 2017

Zhifang Zhang

1

1 reference

4 August 2017

Gregory Cherryholmes

2

1 reference

4 August 2017

Frances Chang

3

1 reference

4 August 2017

David M Rose

4

1 reference

4 August 2017

Ingrid Schraufstatter

5

1 reference

4 August 2017

John E Shively

6

1 reference

4 August 2017

language of work or name

English

0 references

publication date

1 November 2009

1 reference

European Journal of Immunology

4 August 2017

published in

1 reference

4 August 2017

volume

39

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4 August 2017

issue

11

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4 August 2017

page(s)

3181-3194

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Neutrophil secondary necrosis is induced by LL-37 derived from cathelicidin

4 August 2017

cites work

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Human cathelicidin, hCAP-18, is processed to the antimicrobial peptide LL-37 by extracellular cleavage with proteinase 3

8 July 2018

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8 July 2018

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The human antimicrobial and chemotactic peptides LL-37 and alpha-defensins are expressed by specific lymphocyte and monocyte populations

8 July 2018

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8 July 2018

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LL-37, the neutrophil granule- and epithelial cell-derived cathelicidin, utilizes formyl peptide receptor-like 1 (FPRL1) as a receptor to chemoattract human peripheral blood neutrophils, monocytes, and T cells

8 July 2018

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Delayed wound healing in CXCR2 knockout mice

8 July 2018

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GCP-2-induced internalization of IL-8 receptors: hierarchical relationships between GCP-2 and other ELR(+)-CXC chemokines and mechanisms regulating CXCR2 internalization and recycling.

8 July 2018

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Structure and organization of the human antimicrobial peptide LL-37 in phospholipid membranes: relevance to the molecular basis for its non-cell-selective activity

8 July 2018

1 reference

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The role of chemokines in the regulation of dendritic cell trafficking

8 July 2018

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The human cationic antimicrobial protein (hCAP18), a peptide antibiotic, is widely expressed in human squamous epithelia and colocalizes with interleukin-6.

8 July 2018

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Differential regulation of beta1 integrins by chemoattractants regulates neutrophil migration through fibrin

8 July 2018

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Interleukin-8 receptors R1 and R2 activate mitogen-activated protein kinases and induce c-fos, independent of Ras and Raf-1 in Chinese hamster ovary cells

8 July 2018

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Neutrophils stimulated with a variety of chemoattractants exhibit rapid activation of p21-activated kinases (Paks): separate signals are required for activation and inactivation of paks

8 July 2018

1 reference

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High constitutive activity of the human formyl peptide receptor

8 July 2018

1 reference

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Expression and functional activity of the IL-8 receptor type CXCR1 and CXCR2 on human mast cells

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3076219

Identification of a potent, selective non-peptide CXCR2 antagonist that inhibits interleukin-8-induced neutrophil migration

8 July 2018

1 reference

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A G-protein-coupled receptor for leukotriene B4 that mediates chemotaxis

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3076219

Human chemokines: an update

8 July 2018

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Purinergic modulation of interleukin-1 beta release from microglial cells stimulated with bacterial endotoxin

8 July 2018

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Physical association of Gi2alpha with interleukin-8 receptors

8 July 2018

1 reference

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Expression of transcripts for two interleukin 8 receptors in human phagocytes, lymphocytes and melanoma cells

8 July 2018

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The molecular biology of leukocyte chemoattractant receptors

8 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3076219

Human CAP18: a novel antimicrobial lipopolysaccharide-binding protein

8 July 2018

1 reference

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Regulation of the expression of IL-8 receptor A/B by IL-8: possible functions of each receptor

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3076219

Monoclonal antibodies detect different distribution patterns of IL-8 receptor A and IL-8 receptor B on human peripheral blood leukocytes

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3076219

Distributions of melanoma growth stimulatory activity of growth-regulated gene and the interleukin-8 receptor B in human wound repair

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3076219

Superoxide responses of immune complex-stimulated rat alveolar macrophages. Intracellular calcium and priming.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3076219

Cloning of complementary DNA encoding a functional human interleukin-8 receptor

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3076219

Structure and Functional Expression of a Human Interleukin-8 Receptor

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3076219

A novel P2X7 receptor activator, the human cathelicidin-derived peptide LL37, induces IL-1 beta processing and release

8 July 2018

1 reference

Crossref

https://api.crossref.org/works/10.1002%2FEJI.200939496

IL-8/CXCL8 and growth-related oncogene alpha/CXCL1 induce chondrocyte hypertrophic differentiation

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1002%2FEJI.200939496

Depletion of CXCR2 inhibits tumor growth and angiogenesis in a murine model of lung cancer

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1002%2FEJI.200939496

The host defense peptide LL-37 selectively permeabilizes apoptotic leukocytes

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3076219

Cathelicidin LL-37 induces the generation of reactive oxygen species and release of human alpha-defensins from neutrophils

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3076219

The human cationic host defense peptide LL-37 mediates contrasting effects on apoptotic pathways in different primary cells of the innate immune system.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3076219

The macrophage-derived lectin, MNCF, activates neutrophil migration through a pertussis toxin-sensitive pathway

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3076219

Perturbation of the hydrophobic core of lipid bilayers by the human antimicrobial peptide LL-37.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3076219

The mechanism for activation of the neutrophil NADPH-oxidase by the peptides formyl-Met-Leu-Phe and Trp-Lys-Tyr-Met-Val-Met differs from that for interleukin-8.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3076219

A cathelicidin family of human antibacterial peptide LL-37 induces mast cell chemotaxis

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3076219

Signaling pathways activated by chemokine receptor CXCR2 and AMPA-type glutamate receptors and involvement in granule cells survival.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3076219

IL-8 activates endothelial cell CXCR1 and CXCR2 through Rho and Rac signaling pathways

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3076219

Receptor expression and responsiveness of human dendritic cells to a defined set of CC and CXC chemokines

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3076219

Modulation of IL-8 receptor expression on purified human T lymphocytes is associated with changed chemotactic responses to IL-8.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3076219

Flow cytometric kinetic measurements of neutrophil phospholipase A activation

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3076219

The cathelicidin anti-microbial peptide LL-37 is involved in re-epithelialization of human skin wounds and is lacking in chronic ulcer epithelium

26 October 2018

1 reference

12 December 2020

Angiogenic effects of interleukin 8 (CXCL8) in human intestinal microvascular endothelial cells are mediated by CXCR2

1 reference

12 December 2020

Expression of monocyte chemoattractant protein-1 and interleukin-8 receptors on subsets of T cells: correlation with transendothelial chemotactic potential

1 reference

12 December 2020

Recent advances in chemokines and chemokine receptors

1 reference

12 December 2020

Metalloproteinases are involved in lipopolysaccharide- and tumor necrosis factor-alpha-mediated regulation of CXCR1 and CXCR2 chemokine receptor expression

1 reference

12 December 2020

Overexpression of CXC-chemokines and CXC-chemokine receptor type II constitute an autocrine growth mechanism in the epidermoid carcinoma cells KB and A431

1 reference

12 December 2020

Induction of keratinocyte migration via transactivation of the epidermal growth factor receptor by the antimicrobial peptide LL-37

1 reference

12 December 2020

The human antibacterial cathelicidin, hCAP-18, is synthesized in myelocytes and metamyelocytes and localized to specific granules in neutrophils

1 reference

12 December 2020

The CXC-chemokine neutrophil-activating peptide-2 induces two distinct optima of neutrophil chemotaxis by differential interaction with interleukin-8 receptors CXCR-1 and CXCR-2

1 reference

12 December 2020

Neutrophil-activating peptides NAP-2 and IL-8 bind to the same sites on neutrophils but interact in different ways. Discrepancies in binding affinities, receptor densities, and biologic effects

1 reference

12 December 2020

Rapid and coordinated switch in chemokine receptor expression during dendritic cell maturation

1 reference

12 December 2020

Differential regulation of responsiveness to fMLP and C5a upon dendritic cell maturation: correlation with receptor expression

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12 December 2020

Down-regulation of neutrophil functions by the ELR(+) CXC chemokine platelet basic protein

1 reference

12 December 2020

Different G(i)-coupled chemoattractant receptors signal qualitatively different functions in human neutrophils

1 reference

12 December 2020

Identifiers

DOI

10.1002/EJI.200939496

1 reference

4 August 2017

1 reference

4 August 2017

1 reference