(Q41786720)

English

The human cationic host defense peptide LL-37 mediates contrasting effects on apoptotic pathways in different primary cells of the innate immune system.

scientific article published on 22 June 2006

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scholarly article

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Europe PubMed Central

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25 December 2019

The human cationic host defense peptide LL-37 mediates contrasting effects on apoptotic pathways in different primary cells of the innate immune system (English)

1 reference

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25 December 2019

apoptotic process

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1

1 reference

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25 December 2019

Thomas S. Wilkinson

3

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25 December 2019

4

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25 December 2019

8

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25 December 2019

Donald J. Davidson

10

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25 December 2019

Robert E. W. Hancock

9

object named as

Robert E W Hancock

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25 December 2019

author name string

Yuexin Li

2

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25 December 2019

Y Elaine Lau

5

1 reference

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25 December 2019

Celine Cosseau

6

1 reference

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25 December 2019

Christopher Haslett

7

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25 December 2019

publication date

22 June 2006

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25 December 2019

Journal of Leukocyte Biology

1 reference

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25 December 2019

80

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25 December 2019

3

1 reference

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25 December 2019

509-520

1 reference

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25 December 2019

Modulation of the TLR-mediated inflammatory response by the endogenous human host defense peptide LL-37.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1851551

6 June 2018

Apoptosis of airway epithelial cells: human serum sensitive induction by the cathelicidin LL-37.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1851551

6 June 2018

Keratinocyte production of cathelicidin provides direct activity against bacterial skin pathogens

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1851551

6 June 2018

Pseudoapoptosis induced by brief activation of ATP-gated P2X7 receptors.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1851551

6 June 2018

Human endogenous antibiotic LL-37 stimulates airway epithelial cell proliferation and wound closure

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1851551

6 June 2018

Mouse cathelin-related antimicrobial peptide chemoattracts leukocytes using formyl peptide receptor-like 1/mouse formyl peptide receptor-like 2 as the receptor and acts as an immune adjuvant.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1851551

6 June 2018

Immunomodulatory activities of small host defense peptides

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1851551

6 June 2018

Structure-function relationships among human cathelicidin peptides: dissociation of antimicrobial properties from host immunostimulatory activities

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1851551

6 June 2018

LL-37 enhances adaptive antitumor immune response in a murine model when genetically fused with M-CSFR (J6-1) DNA vaccine.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1851551

6 June 2018

Expression of an additional cathelicidin antimicrobial peptide protects against bacterial skin infection.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1851551

6 June 2018

A re-evaluation of the role of host defence peptides in mammalian immunity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1851551

6 June 2018

Interaction and cellular localization of the human host defense peptide LL-37 with lung epithelial cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1851551

6 June 2018

Impact of LL-37 on anti-infective immunity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1851551

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1851551

6 June 2018

C-terminal domain of human CAP18 antimicrobial peptide induces apoptosis in oral squamous cell carcinoma SAS-H1 cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1851551

6 June 2018

P2X7 receptor-mediated apoptosis of human cervical epithelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1851551

6 June 2018

Identification of peptides that antagonize formyl peptide receptor-like 1-mediated signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1851551

6 June 2018

Can innate immunity be enhanced to treat microbial infections?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1851551

6 June 2018

The human cationic peptide LL-37 induces activation of the extracellular signal-regulated kinase and p38 kinase pathways in primary human monocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1851551

6 June 2018

Postsecretory processing generates multiple cathelicidins for enhanced topical antimicrobial defense

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1851551

6 June 2018

The antimicrobial peptide LL-37 activates innate immunity at the airway epithelial surface by transactivation of the epidermal growth factor receptor.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1851551

6 June 2018

Cathelicidins, multifunctional peptides of the innate immunity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1851551

6 June 2018

An angiogenic role for the human peptide antibiotic LL-37/hCAP-18.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1851551

6 June 2018

Neutrophil apoptosis pathways and their modifications in inflammation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1851551

6 June 2018

Protection against enteric salmonellosis in transgenic mice expressing a human intestinal defensin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1851551

6 June 2018

Endogenous antimicrobial peptides and skin infections in atopic dermatitis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1851551

6 June 2018

The human antimicrobial peptide LL-37 is a multifunctional modulator of innate immune responses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1851551

6 June 2018

Antimicrobial peptides of multicellular organisms

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1851551

6 June 2018

Innate antimicrobial peptide protects the skin from invasive bacterial infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1851551

6 June 2018

CD95/CD95 ligand interactions on epithelial cells in host defense to Pseudomonas aeruginosa

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1851551

6 June 2018

LL-37, the neutrophil granule- and epithelial cell-derived cathelicidin, utilizes formyl peptide receptor-like 1 (FPRL1) as a receptor to chemoattract human peripheral blood neutrophils, monocytes, and T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1851551

6 June 2018

Cutting edge: cationic antimicrobial peptides block the binding of lipopolysaccharide (LPS) to LPS binding protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1851551

6 June 2018

Augmentation of innate host defense by expression of a cathelicidin antimicrobial peptide.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1851551

6 June 2018

Regulation of intestinal alpha-defensin activation by the metalloproteinase matrilysin in innate host defense

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1851551

6 June 2018

Antibacterial activity of human neutrophil defensins in experimental infections in mice is accompanied by increased leukocyte accumulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1851551

6 June 2018

Activities of LL-37, a cathelin-associated antimicrobial peptide of human neutrophils

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1851551

6 June 2018

Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1851551

6 June 2018

Bid, a Bcl2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1851551

6 June 2018

Granules of the human neutrophilic polymorphonuclear leukocyte.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1851551

6 June 2018

Antiendotoxin activity of cationic peptide antimicrobial agents

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1851551

6 June 2018

Role of mutant CFTR in hypersusceptibility of cystic fibrosis patients to lung infections.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1851551

6 June 2018

Procedure for isolation of bacterial lipopolysaccharides from both smooth and rough Pseudomonas aeruginosa and Salmonella typhimurium strains.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1851551

6 June 2018

Microbicidal/cytotoxic proteins of neutrophils are deficient in two disorders: Chediak-Higashi syndrome and "specific" granule deficiency

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1851551

6 June 2018

An antimicrobial cathelicidin peptide, human CAP18/LL-37, suppresses neutrophil apoptosis via the activation of formyl-peptide receptor-like 1 and P2X7.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1851551

18 August 2018

Cathelicidin mediates innate intestinal defense against colonization with epithelial adherent bacterial pathogens.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1851551

18 August 2018

Effect of antibacterial cathelicidin peptide CAP18/LL-37 on sepsis in neonatal rats.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1851551

18 August 2018

Beta-defensins and LL-37 in bronchoalveolar lavage fluid of patients with cystic fibrosis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1851551

18 August 2018

A novel P2X7 receptor activator, the human cathelicidin-derived peptide LL37, induces IL-1 beta processing and release

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1851551

18 August 2018

Deficiency of antibacterial peptides in patients with morbus Kostmann: an observation study.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1851551

18 August 2018

A cathelicidin family of human antibacterial peptide LL-37 induces mast cell chemotaxis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1851551

18 August 2018

Increased levels of antimicrobial peptides in tracheal aspirates of newborn infants during infection.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1851551

18 August 2018

Critical role for caspases 3 and 8 in neutrophil but not eosinophil apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1851551

18 August 2018

BCL-2 family expression in human neutrophils during delayed and accelerated apoptosis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1851551

18 August 2018

The synthetic chemoattractant Trp-Lys-Tyr-Met-Val-DMet activates neutrophils preferentially through the lipoxin A(4) receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/16793910

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Granulocyte-macrophage colony-stimulating factor delays neutrophil constitutive apoptosis through phosphoinositide 3-kinase and extracellular signal-regulated kinase pathways

1 reference

https://pubmed.ncbi.nlm.nih.gov/16793910

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Preferential externalization of newly synthesized phosphatidylserine in apoptotic U937 cells is dependent on caspase-mediated pathways

1 reference

https://pubmed.ncbi.nlm.nih.gov/16793910

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The cathelicidin anti-microbial peptide LL-37 is involved in re-epithelialization of human skin wounds and is lacking in chronic ulcer epithelium

1 reference

https://pubmed.ncbi.nlm.nih.gov/16793910

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The cationic antimicrobial peptide LL-37 modulates dendritic cell differentiation and dendritic cell-induced T cell polarization

1 reference

https://pubmed.ncbi.nlm.nih.gov/16793910

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Separation of Leucocytes: Improved Cell Purity by Fine Adjustments of Gradient Medium Density and Osmolality

1 reference

https://pubmed.ncbi.nlm.nih.gov/16793910

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prolongation of survival of human polymorphonuclear neutrophils by granulocyte-macrophage colony-stimulating factor is caused by inhibition of programmed cell death

1 reference

https://pubmed.ncbi.nlm.nih.gov/16793910

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neutrophil apoptosis is associated with a reduction in CD16 (Fc gamma RIII) expression

1 reference

https://pubmed.ncbi.nlm.nih.gov/16793910

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Induction and evasion of host defenses by type 1-piliated uropathogenic Escherichia coli

1 reference

https://pubmed.ncbi.nlm.nih.gov/16793910

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Endotoxin inhibits apoptosis but induces primary necrosis in neutrophils

1 reference

https://pubmed.ncbi.nlm.nih.gov/16793910

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human cathelicidin LL-37 is a chemoattractant for eosinophils and neutrophils that acts via formyl-peptide receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/16793910

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1189/JLB.1005560

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16793910%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16793910%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16793910%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

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