(Q34792618)

4 August 2017

4 references

19 September 2019

27 November 2019

13 December 2019

22 August 2022

Omics meets biology: application to the design and preclinical assessment of antivenoms (English)

1 reference

biomedical investigative technique

4 August 2017

main subject

1 reference

19 September 2019

1 reference

27 November 2019

1 reference

13 December 2019

1

1 reference

4 August 2017

2

1 reference

4 August 2017

3

1 reference

4 August 2017

Bruno Lomonte

4

0 references

José María Gutiérrez

object named as

José María Gutiérrez

series ordinal

5

0 references

publication date

15 December 2014

5 references

4 August 2017

19 September 2019

27 November 2019

13 December 2019

22 August 2022

5 references

4 August 2017

19 September 2019

27 November 2019

13 December 2019

22 August 2022

6

1 reference

4 August 2017

issue

12

1 reference

4 August 2017

page(s)

3388-3405

1 reference

Creative Commons Attribution

4 August 2017

copyright license

4 references

19 September 2019

27 November 2019

13 December 2019

22 August 2022

0 references

A multicomponent strategy to improve the availability of antivenom for treating snakebite envenoming

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4280540

Medically important differences in snake venom composition are dictated by distinct postgenomic mechanisms

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4280540

Next-generation snake venomics: protein-locus resolution through venom proteome decomplexation

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4280540

Immunological profile of antivenoms: preclinical analysis of the efficacy of a polyspecific antivenom through antivenomics and neutralization assays

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4280540

Venomous snakes of Costa Rica: biological and medical implications of their venom proteomic profiles analyzed through the strategy of snake venomics

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4280540

Venomics of New World pit vipers: genus-wide comparisons of venom proteomes across Agkistrodon

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4280540

New approaches & technologies of venomics to meet the challenge of human envenoming by snakebites in India

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4280540

The venom-gland transcriptome of the eastern coral snake (Micrurus fulvius) reveals high venom complexity in the intragenomic evolution of venoms

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4280540

Phylogeny-based comparative analysis of venom proteome variation in a clade of rattlesnakes (Sistrurus sp.)

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4280540

The need for full integration of snakebite envenoming within a global strategy to combat the neglected tropical diseases: the way forward

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4280540

Snake venomics: from the inventory of toxins to biology

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4280540

Integrated "omics" profiling indicates that miRNAs are modulators of the ontogenetic venom composition shift in the Central American rattlesnake, Crotalus simus simus

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4280540

The venom-gland transcriptome of the eastern diamondback rattlesnake (Crotalus adamanteus)

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4280540

Improving antivenom availability and accessibility: science, technology, and beyond

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4280540

Venom variability and envenoming severity outcomes of the Crotalus scutulatus scutulatus (Mojave rattlesnake) from Southern Arizona

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4280540

Proteomic tools against the neglected pathology of snake bite envenoming

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4280540

Research strategies to improve snakebite treatment: challenges and progress.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4280540

Ending the drought: new strategies for improving the flow of affordable, effective antivenoms in Asia and Africa

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4280540

Preclinical evaluation of caprylic acid-fractionated IgG antivenom for the treatment of Taipan (Oxyuranus scutellatus) envenoming in Papua New Guinea

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4280540

Antivenoms for the treatment of snakebite envenomings: the road ahead

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4280540

Deconstructing a complex molecular phenotype: population-level variation in individual venom proteins in Eastern Massasauga Rattlesnakes (Sistrurus c. catenatus).

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4280540

Snake venomics of African spitting cobras: toxin composition and assessment of congeneric cross-reactivity of the pan-African EchiTAb-Plus-ICP antivenom by antivenomics and neutralization approaches

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4280540

Snake venomics of Bothriechis nigroviridis reveals extreme variability among palm pitviper venoms: different evolutionary solutions for the same trophic purpose

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4280540

Snake venomics and antivenomics of Crotalus durissus subspecies from Brazil: assessment of geographic variation and its implication on snakebite management

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4280540

The Global Snake Bite Initiative: an antidote for snake bite

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4280540

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4280540

Snake envenoming: a disease of poverty

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4280540

Snakebite envenoming from a global perspective: Towards an integrated approach

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4280540

Snake venomics of the Central American rattlesnake Crotalus simus and the South American Crotalus durissus complex points to neurotoxicity as an adaptive paedomorphic trend along Crotalus dispersal in South America

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4280540

Proteome analysis of snake venom toxins: pharmacological insights

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4280540

Combined snake venomics and venom gland transcriptomic analysis of the ocellated carpet viper, Echis ocellatus

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4280540

The global burden of snakebite: a literature analysis and modelling based on regional estimates of envenoming and deaths

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4280540

Exploring snake venom proteomes: multifaceted analyses for complex toxin mixtures.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4280540

Snake venomics. Strategy and applications

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4280540

Thrombocytopenia and platelet hypoaggregation induced by Bothrops asper snake venom. Toxins involved and their contribution to metalloproteinase-induced pulmonary hemorrhage

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4280540

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4280540

Report of a WHO workshop on the standardization and control of antivenoms

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4280540

Doctor Albert Calmette 1863-1933: founder of antivenomous serotherapy and of antituberculous BCG vaccination

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4280540

Development of simple standard assay procedures for the characterization of snake venom

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4280540

Comparative study on coagulant, defibrinating, fibrinolytic and fibrinogenolytic activities of Costa Rican crotaline snake venoms and their neutralization by a polyvalent antivenom

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4280540

Snake venom variability: methods of study, results and interpretation.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4280540

Assessing the preclinical efficacy of antivenoms: from the lethality neutralization assay to antivenomics

8 July 2018

1 reference

https://api.crossref.org/works/10.3390%2FTOXINS6123388

Pulmonary hemorrhage induced by jararhagin, a metalloproteinase from Bothrops jararaca snake venom

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FTOXINS6123388

Neutrophils do not contribute to local tissue damage, but play a key role in skeletal muscle regeneration, in mice injected with Bothrops asper snake venom

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FTOXINS6123388

Neutralization of four Peruvian Bothrops sp. snake venoms by polyvalent antivenoms produced in Perú and Costa Rica: preclinical assessment

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FTOXINS6123388

Absorption of 3-oxy-methyl-D-glucose by chicken cecum and jejunum in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FTOXINS6123388

Snake venomics of the Lesser Antillean pit vipers Bothrops caribbaeus and Bothrops lanceolatus: correlation with toxicological activities and immunoreactivity of a heterologous antivenom

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FTOXINS6123388

Linking the transcriptome and proteome to characterize the venom of the eastern diamondback rattlesnake (Crotalus adamanteus).

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FTOXINS6123388

Combined venom gland cDNA sequencing and venomics of the New Guinea small-eyed snake, Micropechis ikaheka

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FTOXINS6123388

Snake venomics of the lancehead pitviper Bothrops asper: geographic, individual, and ontogenetic variations.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FTOXINS6123388

Bothrops jararaca venom proteome rearrangement upon neonate to adult transition

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FTOXINS6123388

Comparative analysis of newborn and adult Bothrops jararaca snake venoms

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FTOXINS6123388

Intraspecific venom variation in the medically significant Southern Pacific Rattlesnake (Crotalus oreganus helleri): biodiscovery, clinical and evolutionary implications

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FTOXINS6123388

Proteomic analysis of ontogenetic and diet-related changes in venom composition of juvenile and adult Dusky Pigmy rattlesnakes (Sistrurus miliarius barbouri).

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FTOXINS6123388

Snake venomics of Lachesis muta rhombeata and genus-wide antivenomics assessment of the paraspecific immunoreactivity of two antivenoms evidence the high compositional and immunological conservation across Lachesis

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FTOXINS6123388

Proteomic and biochemical analyses of short-tailed pit viper (Gloydius brevicaudus) venom: age-related variation and composition-activity correlation

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FTOXINS6123388

Niche divergence and lineage diversification among closely related Sistrurus rattlesnakes.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FTOXINS6123388

Snake venomics and antivenomics of the arboreal neotropical pitvipers Bothriechis lateralis and Bothriechis schlegelii

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FTOXINS6123388

Preclinical efficacy of Australian antivenoms against the venom of the small-eyed snake, Micropechis ikaheka, from Papua New Guinea: an antivenomics and neutralization study

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FTOXINS6123388

Pan-African polyspecific antivenom produced by caprylic acid purification of horse IgG: an alternative to the antivenom crisis in Africa

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FTOXINS6123388

Mionecrosis, hemorragia y edema inducidos por el veneno de Bothrops asper en ratón blanco

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FTOXINS6123388

Neutralization of proteolytic and hemorrhagic activities of Costa Rican snake venoms by a polyvalent antivenom

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FTOXINS6123388

Neutralization of hyaluronidase and indirect hemolytic activities of Costa Rican snake venoms by a polyvalent antivenom

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FTOXINS6123388

Standardization of assays for testing the neutralizing ability of antivenoms

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FTOXINS6123388

Snake population venomics and antivenomics of Bothrops atrox: Paedomorphism along its transamazonian dispersal and implications of geographic venom variability on snakebite management

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FTOXINS6123388

Snake venomics across genus Lachesis. Ontogenetic changes in the venom composition of Lachesis stenophrys and comparative proteomics of the venoms of adult Lachesis melanocephala and Lachesis acrochorda

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FTOXINS6123388

Second generation snake antivenomics: Comparing immunoaffinity and immunodepletion protocols

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FTOXINS6123388

Preclinical assessment of a polyspecific antivenom against the venoms of Cerrophidion sasai, Porthidium nasutum and Porthidium ophryomegas: Insights from combined antivenomics and neutralization assays

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FTOXINS6123388

Studies on the quantitative method for determination of hemorrhagic activity of Habu snake venom

21 January 2018

1 reference

12 December 2020

Purification of a neurotoxin from the venom of Naja nigricollis

1 reference

12 December 2020

Comparative study of the edema-forming activity of costa rican snake venoms and its neutralization by a polyvalent antivenom

1 reference

12 December 2020

The use of the chick biventer cervicis preparation to assess the protective activity of six international reference antivenoms on the neuromuscular effects of snake venoms in vitro

1 reference

12 December 2020

Identifiers

DOI

10.3390/TOXINS6123388

1 reference

4 August 2017

1 reference

4 August 2017

1 reference