(Q34792862)

4 August 2017

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title

Structure-based design of cyclin-dependent kinase inhibitors (English)

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4 August 2017

4

Louise N Johnson

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4 August 2017

Thomas G Davies

1

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4 August 2017

David J Pratt

series ordinal

2

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4 August 2017

Jane A Endicott

series ordinal

3

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4 August 2017

Martin E M Noble

series ordinal

5

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4 August 2017

publication date

1 February 2002

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Pharmacology & Therapeutics

4 August 2017

published in

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4 August 2017

volume

93

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4 August 2017

issue

2-3

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4 August 2017

page(s)

125-133

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Identification of novel purine and pyrimidine cyclin-dependent kinase inhibitors with distinct molecular interactions and tumor cell growth inhibition profiles

4 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2802%2900182-1

7 January 2021

Prediction of binding constants of protein ligands: a fast method for the prioritization of hits obtained from de novo design or 3D database search programs

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2802%2900182-1

7 January 2021

The structural basis for specificity of substrate and recruitment peptides for cyclin-dependent kinases

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2802%2900182-1

7 January 2021

Selective killing of transformed cells by cyclin/cyclin-dependent kinase 2 antagonists

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2802%2900182-1

7 January 2021

Initial sequencing and analysis of the human genome

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2802%2900182-1

7 January 2021

Inhibitor binding to active and inactive CDK2: the crystal structure of CDK2-cyclin A/indirubin-5-sulphonate

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2802%2900182-1

7 January 2021

Prevention of chemotherapy-induced alopecia in rats by CDK inhibitors

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2802%2900182-1

7 January 2021

Inhibition of cyclin-dependent kinases by purine analogues: crystal structure of human cdk2 complexed with roscovitine

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2802%2900182-1

7 January 2021

Structural basis for specificity and potency of a flavonoid inhibitor of human CDK2, a cell cycle kinase.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2802%2900182-1

7 January 2021

Crystal structure of cyclin-dependent kinase 2

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2802%2900182-1

7 January 2021

Win some, lose some: enthalpy-entropy compensation in weak intermolecular interactions

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2802%2900182-1

7 January 2021

The regulation of E2F by pRB-family proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2802%2900182-1

7 January 2021

Cyclin-dependent kinases: inhibition and substrate recognition.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2802%2900182-1

7 January 2021

A specific inhibitor of the epidermal growth factor receptor tyrosine kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2802%2900182-1

7 January 2021

Exploiting chemical libraries, structure, and genomics in the search for kinase inhibitors

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2802%2900182-1

7 January 2021

Acquisition of sensitivity of stress-activated protein kinases to the p38 inhibitor, SB 203580, by alteration of one or more amino acids within the ATP binding pocket

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2802%2900182-1

7 January 2021

Genetic alterations of cyclins, cyclin-dependent kinases, and Cdk inhibitors in human cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2802%2900182-1

7 January 2021

The Rb/E2F pathway: expanding roles and emerging paradigms

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2802%2900182-1

7 January 2021

Indirubin, the active constituent of a Chinese antileukaemia medicine, inhibits cyclin-dependent kinases

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2802%2900182-1

7 January 2021

Mechanism of CDK activation revealed by the structure of a cyclinA-CDK2 complex

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2802%2900182-1

7 January 2021

Cell-cycle regulators and cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2802%2900182-1

7 January 2021

Cyclin A-kinase regulation of E2F-1 DNA binding function underlies suppression of an S phase checkpoint

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2802%2900182-1

7 January 2021

Protein kinase inhibition by staurosporine revealed in details of the molecular interaction with CDK2

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2802%2900182-1

7 January 2021

p38 mitogen-activated protein kinase inhibitors--mechanisms and therapeutic potentials

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2802%2900182-1

7 January 2021

Cyclin-Dependent Kinase Inhibition by New C-2 Alkynylated Purine Derivatives and Molecular Structure of a CDK2−Inhibitor Complex

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2802%2900182-1

7 January 2021

Chemical inhibitors of cyclin-dependent kinases

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2802%2900182-1

7 January 2021

Inhibition of cyclin-dependent kinases, GSK-3beta and CK1 by hymenialdisine, a marine sponge constituent

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2802%2900182-1

7 January 2021

Cyclin-dependent kinases: engines, clocks, and microprocessors

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2802%2900182-1

7 January 2021

Chemical inhibitors of cyclin-dependent kinases: insights into design from X-ray crystallographic studies.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2802%2900182-1

7 January 2021

Staurosporine, a potentially important gift from a microorganism.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2802%2900182-1

7 January 2021

Mechanisms of cyclin-dependent kinase regulation: structures of Cdks, their cyclin activators, and Cip and INK4 inhibitors

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2802%2900182-1

7 January 2021

Structural basis of cyclin-dependent kinase activation by phosphorylation

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2802%2900182-1

7 January 2021

Multiple modes of ligand recognition: crystal structures of cyclin-dependent protein kinase 2 in complex with ATP and two inhibitors, olomoucine and isopentenyladenine

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2802%2900182-1

7 January 2021

High-resolution crystal structures of human cyclin-dependent kinase 2 with and without ATP: bound waters and natural ligand as guides for inhibitor design

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2802%2900182-1

7 January 2021

Preclinical and clinical development of cyclin-dependent kinase modulators

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2802%2900182-1

7 January 2021

Anticancer drug targets: cell cycle and checkpoint control.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2802%2900182-1

7 January 2021

A highly specific inhibitor of human p38 MAP kinase binds in the ATP pocket

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2802%2900182-1

7 January 2021

The Sequence of the Human Genome

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2802%2900182-1

7 January 2021

Inhibition of cyclin-dependent kinases by purine analogues.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2802%2900182-1

7 January 2021

Active transcriptional repression by the Rb-E2F complex mediates G1 arrest triggered by p16INK4a, TGFbeta, and contact inhibition

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2802%2900182-1

7 January 2021

The eukaryotic protein kinase superfamily: kinase (catalytic) domain structure and classification 1

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2802%2900182-1

7 January 2021

10.1016/S0163-7258(02)00182-1

Identifiers

DOI

1 reference

release_42sqooybenfm7nsjhq6mj3hutq

4 August 2017

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/42sqooybenfm7nsjhq6mj3hutq

24 November 2022

mapped directly with Wikidata item

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