(Q34792950)

25489101

4 August 2017

title

Impact of an immune modulator fingolimod on acute ischemic stroke (English)

1 reference

4 August 2017

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25489101%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

Junwei Hao

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25489101%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

author name string

Ying Fu

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25489101%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

Ningnannan Zhang

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25489101%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

Yaping Yan

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25489101%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

Na Sun

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25489101%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

Yu-Jing Li

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25489101%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

Wei Han

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25489101%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

Rong Xue

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25489101%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

Qiang Liu

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25489101%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

Chunshui Yu

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25489101%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

Fu-Dong Shi

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25489101%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

language of work or name

English

0 references

publication date

8 December 2014

1 reference

25489101

Proceedings of the National Academy of Sciences of the United States of America

4 August 2017

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25489101%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

volume

111

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25489101%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

issue

51

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25489101%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

page(s)

18315-18320

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25489101%20AND%20SRC:MED&resulttype=core&format=json

Fingolimod for the treatment of intracerebral hemorrhage: a 2-arm proof-of-concept study

11 June 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4280578

Ischemic neurons recruit natural killer cells that accelerate brain infarction

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4280578

FTY720 treatment in the convalescence period improves functional recovery and reduces reactive astrogliosis in photothrombotic stroke

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4280578

Advances and challenges in treatment and prevention of ischemic stroke

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4280578

Intravenous minocycline in acute stroke: a randomized, controlled pilot study and meta-analysis

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4280578

Fingolimod reduces hemorrhagic transformation associated with delayed tissue plasminogen activator treatment in a mouse thromboembolic model

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4280578

Targeting blood-brain barrier sphingolipid signaling reduces basal P-glycoprotein activity and improves drug delivery to the brain

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4280578

The immunology of acute stroke

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4280578

Blood-brain barrier breakdown in acute and chronic cerebrovascular disease

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4280578

The immunology of stroke: from mechanisms to translation

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4280578

FTY720 reduces post-ischemic brain lymphocyte influx but does not improve outcome in permanent murine cerebral ischemia

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4280578

How to make better use of thrombolytic therapy in acute ischemic stroke

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4280578

Mechanisms of fingolimod's efficacy and adverse effects in multiple sclerosis

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4280578

Treatment with the immunomodulator FTY720 does not promote spontaneous bacterial infections after experimental stroke in mice

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4280578

8 July 2018

Hypoxia and inflammation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4280578

Fingolimod provides long-term protection in rodent models of cerebral ischemia

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4280578

Inflammation after stroke: mechanisms and therapeutic approaches

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4280578

Time to treatment with intravenous alteplase and outcome in stroke: an updated pooled analysis of ECASS, ATLANTIS, NINDS, and EPITHET trials

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4280578

A placebo-controlled trial of oral fingolimod in relapsing multiple sclerosis

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4280578

Activation of sphingosine 1-phosphate receptor-1 by FTY720 is neuroprotective after ischemic stroke in rats.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4280578

Hypoxic preconditioning-induced cerebral ischemic tolerance: role of microvascular sphingosine kinase 2.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4280578

Thrombolysis with alteplase 3 to 4.5 hours after acute ischemic stroke

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4280578

Establishing final infarct volume: stroke lesion evolution past 30 days is insignificant

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4280578

Autoimmune T cells protect neurons from secondary degeneration after central nervous system axotomy

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4280578

Enlargement of human cerebral ischemic lesion volumes measured by diffusion-weighted magnetic resonance imaging

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4280578

'Malignant' middle cerebral artery territory infarction: clinical course and prognostic signs.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4280578

Human cerebral infarct: a proposed histopathologic classification based on 137 cases.

8 July 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1416166111

Early detrimental T-cell effects in experimental cerebral ischemia are neither related to adaptive immunity nor thrombus formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1416166111

Pivotal role of cerebral interleukin-17-producing gammadeltaT cells in the delayed phase of ischemic brain injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1416166111

Lymphocyte sequestration through S1P lyase inhibition and disruption of S1P gradients

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1416166111

The immunomodulatory sphingosine 1-phosphate analog FTY720 reduces lesion size and improves neurological outcome in a mouse model of cerebral ischemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1416166111

Activation of sphingosine kinase 2 is an endogenous protective mechanism in cerebral ischemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1416166111

FTY720 ameliorates acute ischemic stroke in mice by reducing thrombo-inflammation but not by direct neuroprotection.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1416166111

Effects of microvascular permeability changes on contrast-enhanced T1 and pharmacokinetic MR imagings after ischemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1416166111

First human trial of FTY720, a novel immunomodulator, in stable renal transplant patients

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4280578

Inhibition of lymphocyte trafficking shields the brain against deleterious neuroinflammation after stroke

26 October 2018

1 reference

PubMed

12 December 2020

1 reference

12 December 2020

Fingolimod and sphingosine-1-phosphate--modifiers of lymphocyte migration

1 reference

PubMed

12 December 2020

Time course of lesion development in patients with acute stroke: serial diffusion- and hemodynamic-weighted magnetic resonance imaging

1 reference

PubMed

12 December 2020

Identifiers

DOI

10.1073/PNAS.1416166111

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25489101%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25489101%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

25489101

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25489101%20AND%20SRC:MED&resulttype=core&format=json