(Q34805156)

4 August 2017

title

Heparan sulfate/heparin promotes transthyretin fibrillization through selective binding to a basic motif in the protein (English)

1 reference

identical protein binding

4 August 2017

0 references

1 reference

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

8

Jenny Presto

1 reference

4 August 2017

Paul O'Callaghan

2

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Jan Johansson

object named as

Jan Johansson

9

0 references

Maria João Saraiva

object named as

Maria J Saraiva

10

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author name string

Fredrik Noborn

1

1 reference

4 August 2017

Erik Hermansson

3

1 reference

4 August 2017

Xiao Zhang

4

1 reference

4 August 2017

John B Ancsin

5

1 reference

4 August 2017

Ana M Damas

6

1 reference

4 August 2017

Ingrid Dacklin

7

1 reference

4 August 2017

Erik Lundgren

11

1 reference

4 August 2017

Robert Kisilevsky

12

1 reference

4 August 2017

Per Westermark

13

1 reference

4 August 2017

Jin-Ping Li

14

1 reference

4 August 2017

language of work or name

English

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publication date

21 March 2011

1 reference

Proceedings of the National Academy of Sciences of the United States of America

4 August 2017

published in

1 reference

4 August 2017

volume

108

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4 August 2017

issue

14

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4 August 2017

page(s)

5584-5589

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Sulfated glycosaminoglycans accelerate transthyretin amyloidogenesis by quaternary structural conversion

4 August 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3078407

Heparan sulfate mediates amyloid-beta internalization and cytotoxicity

8 July 2018

1 reference

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Evolutionary changes to transthyretin: structure-function relationships

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3078407

Transthyretin: the servant of many masters.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3078407

Heparan sulfate promotes the aggregation of HDL-associated serum amyloid A: evidence for a proamyloidogenic histidine molecular switch

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3078407

Serum transthyretin levels in senile systemic amyloidosis: effects of age, gender and ethnicity

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3078407

Structural insight into pH-induced conformational changes within the native human transthyretin tetramer

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3078407

Heparan sulfate accumulation with Abeta deposits in Alzheimer's disease and Tg2576 mice is contributed by glial cells

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3078407

Heparan sulfate as a therapeutic target in amyloidogenesis: prospects and possible complications

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3078407

Transthyretin and familial amyloidotic polyneuropathy. Recent progress in understanding the molecular mechanism of neurodegeneration

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3078407

Interactions between heparan sulfate and proteins: the concept of specificity

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3078407

Partitioning conformational intermediates between competing refolding and aggregation pathways: insights into transthyretin amyloid disease.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3078407

In vivo fragmentation of heparan sulfate by heparanase overexpression renders mice resistant to amyloid protein A amyloidosis

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3078407

A unique pathway of cardiac myocyte death caused by hypoxia-acidosis.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3078407

Novel Glycosaminoglycan Precursors as Anti-Amyloid Agents, Part III

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3078407

Amyloidogenesis: historical and modern observations point to heparan sulfate proteoglycans as a major culprit

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3078407

Heparan sulphate proteoglycans in Alzheimer's disease and amyloid-related disorders

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3078407

Inhibition of amyloidosis using low-molecular-weight heparins

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3078407

Capture of a dimeric intermediate during transthyretin amyloid formation

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3078407

Heparin oligosaccharides that pass the blood-brain barrier inhibit beta-amyloid precursor protein secretion and heparin binding to beta-amyloid peptide.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3078407

Transthyretin quaternary and tertiary structural changes facilitate misassembly into amyloid.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3078407

Characterization of heparin and heparan sulfate domains binding to the long splice variant of platelet-derived growth factor A chain

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3078407

Amyloid fibril protein in familial amyloidotic polyneuropathy, Portuguese type. Definition of molecular abnormality in transthyretin (prealbumin).

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3078407

Studies on the Protein-Protein and Protein-Ligand Interactions Involved in Retinol Transport in Plasma

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3078407

Animal cell mutants defective in glycosaminoglycan biosynthesis

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3078407

Fluorometric determination of amyloid fibrils in vitro using the fluorescent dye, thioflavin T1.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3078407

Sulfated glycosaminoglycans: a common constituent of all amyloids?

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3078407

Fibril in senile systemic amyloidosis is derived from normal transthyretin

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3078407

Structure of prealbumin: secondary, tertiary and quaternary interactions determined by Fourier refinement at 1.8 A

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3078407

Amyloid in the Aged Heart: Frequency and Clinical Significance

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3078407

Misfolded transthyretin causes behavioral changes in a Drosophila model for transthyretin-associated amyloidosis.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3078407

Arresting amyloidosis in vivo using small-molecule anionic sulphonates or sulphates: implications for Alzheimer's disease

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3078407

Tabulation of human transthyretin (TTR) variants, 2003

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3078407

Nitrocellulose Filter Binding to Assess Binding of Glycosaminoglycans to Proteins

9 December 2018

1 reference

12 December 2020

Frequency and distribution of senile cardiovascular amyloid. A clinicopathologic correlation

1 reference

12 December 2020

Evidence that the amyloid fibril protein in senile systemic amyloidosis is derived from normal prealbumin

1 reference

12 December 2020

Cardiac amyloidosis: report of a patient heterozygous for the transthyretin isoleucine 122 variant

1 reference

12 December 2020

Heparin-binding properties of the amyloidogenic peptides Abeta and amylin. Dependence on aggregation state and inhibition by Congo red

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.1101194108

1 reference

4 August 2017

0 references

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4 August 2017

1 reference