(Q34813347)

4 August 2017

title

Neurobiological effects of sphingosine 1-phosphate receptor modulation in the cuprizone model (English)

1 reference

4 August 2017

1 reference

Veronique E Miron

2

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Richard L. Proia

object named as

Richard L Proia

4

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author name string

Hye Jung Kim

1

1 reference

4 August 2017

Danuta Dukala

3

1 reference

4 August 2017

Samuel K Ludwin

5

1 reference

4 August 2017

Maria Traka

6

1 reference

4 August 2017

Jack P Antel

7

1 reference

4 August 2017

Betty Soliven

8

1 reference

4 August 2017

language of work or name

English

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publication date

19 January 2011

1 reference

4 August 2017

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4 August 2017

volume

25

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4 August 2017

issue

5

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4 August 2017

page(s)

1509-1518

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FTY720 (fingolimod) efficacy in an animal model of multiple sclerosis requires astrocyte sphingosine 1-phosphate receptor 1 (S1P1) modulation

4 August 2017

cites work

1 reference

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Sphingosine 1-phosphate receptor 1 and 3 are upregulated in multiple sclerosis lesions

8 July 2018

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Fingolimod (FTY720) enhances remyelination following demyelination of organotypic cerebellar slices.

8 July 2018

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Inhibiting poly(ADP-ribose) polymerase: a potential therapy against oligodendrocyte death.

8 July 2018

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Oral fingolimod or intramuscular interferon for relapsing multiple sclerosis

8 July 2018

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8 July 2018

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Sphingosine kinase 1 regulates the expression of proinflammatory cytokines and nitric oxide in activated microglia.

8 July 2018

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8 July 2018

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FTY720 reduces inflammation and promotes functional recovery after spinal cord injury

8 July 2018

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Recovery from chronic demyelination by thyroid hormone therapy: myelinogenesis induction and assessment by diffusion tensor magnetic resonance imaging

8 July 2018

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MHC class II exacerbates demyelination in vivo independently of T cells

8 July 2018

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Cyclical and dose-dependent responses of adult human mature oligodendrocytes to fingolimod.

8 July 2018

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Sphingosine kinase 1/S1P receptor signaling axis controls glial proliferation in mice with Sandhoff disease.

8 July 2018

1 reference

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Platelet-derived growth factor promotes repair of chronically demyelinated white matter.

8 July 2018

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FTY720 modulates human oligodendrocyte progenitor process extension and survival.

8 July 2018

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Brain penetration of the oral immunomodulatory drug FTY720 and its phosphorylation in the central nervous system during experimental autoimmune encephalomyelitis: consequences for mode of action in multiple sclerosis

8 July 2018

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Microglial recruitment, activation, and proliferation in response to primary demyelination

8 July 2018

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Activation of sphingosine-1-phosphate receptor S1P5 inhibits oligodendrocyte progenitor migration.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3079302

Immunosuppressive and anti-angiogenic sphingosine 1-phosphate receptor-1 agonists induce ubiquitinylation and proteasomal degradation of the receptor

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3079302

Phosphorylation of the immunomodulatory drug FTY720 by sphingosine kinases

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3079302

Sphingosine-1-phosphate: an enigmatic signalling lipid

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3079302

Disruption of Cnp1 uncouples oligodendroglial functions in axonal support and myelination

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3079302

Sphingosine 1-phosphate induces the production of glial cell line-derived neurotrophic factor and cellular proliferation in astrocytes

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3079302

FTY720: targeting G-protein-coupled receptors for sphingosine 1-phosphate in transplantation and autoimmunity

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3079302

The immune modulator FTY720 targets sphingosine 1-phosphate receptors

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3079302

Alteration of lymphocyte trafficking by sphingosine-1-phosphate receptor agonists

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3079302

Absence of monocyte chemoattractant protein 1 in mice leads to decreased local macrophage recruitment and antigen-specific T helper cell type 1 immune response in experimental autoimmune encephalomyelitis

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3079302

Insulin-like growth factor I gene expression is induced in astrocytes during experimental demyelination

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3079302

Central nervous system demyelination and remyelination in the mouse: an ultrastructural study of cuprizone toxicity

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3079302

Sphingosine 1-phosphate induces expression of early growth response-1 and fibroblast growth factor-2 through mechanism involving extracellular signal-regulated kinase in astroglial cells.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3079302

Functional recovery of callosal axons following demyelination: a critical window

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3079302

Persistent signaling induced by FTY720-phosphate is mediated by internalized S1P1 receptors.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3079302

Chronic toxic demyelination in the central nervous system leads to axonal damage despite remyelination

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3079302

Activation of inflammatory response by a combination of growth factors in cuprizone-induced demyelinated brain leads to myelin repair

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3079302

Sequential myelin protein expression during remyelination reveals fast and efficient repair after central nervous system demyelination.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3079302

Functional consequences of S1P receptor modulation in rat oligodendroglial lineage cells.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3079302

The immunomodulator FTY720 has a direct cytoprotective effect in oligodendrocyte progenitors

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3079302

Phosphorylated FTY720 promotes astrocyte migration through sphingosine-1-phosphate receptors

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3079302

Sphingosine-1-phosphate is released by cerebellar astrocytes in response to bFGF and induces astrocyte proliferation through Gi-protein-coupled receptors.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3079302

Sphingosine 1-phosphate type 1 receptor agonism inhibits transendothelial migration of medullary T cells to lymphatic sinuses

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3079302

Edg8/S1P5: an oligodendroglial receptor with dual function on process retraction and cell survival.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3079302

K+ channel blockade impairs remyelination in the cuprizone model

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3079302

Sphingosine 1-phosphate receptor agonists attenuate relapsing-remitting experimental autoimmune encephalitis in SJL mice.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3079302

Platelet-derived growth factor regulates oligodendrocyte progenitor numbers in adult CNS and their response following CNS demyelination.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3079302

The immunosuppressant FTY720 down-regulates sphingosine 1-phosphate G-protein-coupled receptors

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3079302

Microglial activation state and lysophospholipid acid receptor expression

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3079302

Characterization of lysophosphatidic acid and sphingosine-1-phosphate-mediated signal transduction in rat cortical oligodendrocytes

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3079302

Pharmacological characterization of lysophospholipid receptor signal transduction pathways in rat cerebrocortical astrocytes.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3079302

G-protein-coupled receptor S1P1 acts within endothelial cells to regulate vascular maturation.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3079302

Amelioration of experimental autoimmune encephalomyelitis in Lewis rats by FTY720 treatment

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3079302

PDGF upregulates delayed rectifier via Src family kinases and sphingosine kinase in oligodendroglial progenitors

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3079302

TNF alpha promotes proliferation of oligodendrocyte progenitors and remyelination

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3079302

Interleukin-1beta promotes repair of the CNS.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3079302

Regulation of mitogen-activated protein kinases by sphingolipid products in oligodendrocytes.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3079302

Microglial/macrophage accumulation during cuprizone-induced demyelination in C57BL/6 mice

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3079302

Gene expression in brain during cuprizone-induced demyelination and remyelination

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3079302

Myelination in the absence of galactocerebroside and sulfatide: normal structure with abnormal function and regional instability.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3079302

Mature oligodendrocyte apoptosis precedes IGF-1 production and oligodendrocyte progenitor accumulation and differentiation during demyelination/remyelination

26 October 2018

1 reference

12 December 2020

Insulin-like growth factor-1 inhibits mature oligodendrocyte apoptosis during primary demyelination

1 reference

12 December 2020

Sphingosine-1-phosphate induces proliferation of astrocytes: regulation by intracellular signalling cascades

1 reference

12 December 2020

FTY720 sustains and restores neuronal function in the DA rat model of MOG-induced experimental autoimmune encephalomyelitis

1 reference

12 December 2020

Identifiers

DOI

10.1096/FJ.10-173203

1 reference

4 August 2017

1 reference

4 August 2017

1 reference