(Q34816365)

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Rapid nontranscriptional activation of endothelial nitric oxide synthase mediates increased cerebral blood flow and stroke protection by corticosteroids.

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12464678%20AND%20SRC:MED&resulttype=core&format=json

15 December 2019

Rapid nontranscriptional activation of endothelial nitric oxide synthase mediates increased cerebral blood flow and stroke protection by corticosteroids (English)

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12464678%20AND%20SRC:MED&resulttype=core&format=json

15 December 2019

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cerebral blood flow

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Florian P Limbourg

1

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15 December 2019

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James K Liao

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15 December 2019

Jean-Christophe Plumier

3

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Jean-Christophe Plumier

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15 December 2019

2

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Zhihong Huang

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15 December 2019

Tommaso Simoncini

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Tommaso Simoncini

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15 December 2019

6

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Jan Tuckermann

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15 December 2019

author name string

Masayuki Fujioka

5

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15 December 2019

Günther Schütz

7

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15 December 2019

Michael A Moskowitz

8

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15 December 2019

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1 December 2002

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15 December 2019

Journal of Clinical Investigation

1 reference

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15 December 2019

110

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15 December 2019

11

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Europe PubMed Central

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15 December 2019

1729-1738

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12464678%20AND%20SRC:MED&resulttype=core&format=json

15 December 2019

Acute cardiovascular protective effects of corticosteroids are mediated by non-transcriptional activation of endothelial nitric oxide synthase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151626

8 July 2018

Nongenotropic, sex-nonspecific signaling through the estrogen or androgen receptors: dissociation from transcriptional activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151626

8 July 2018

High-dose methylprednisolone treatment in experimental focal cerebral ischemia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151626

8 July 2018

Protein kinase SGK mediates survival signals by phosphorylating the forkhead transcription factor FKHRL1 (FOXO3a)

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151626

8 July 2018

Mice with an increased glucocorticoid receptor gene dosage show enhanced resistance to stress and endotoxic shock

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151626

8 July 2018

Membrane estrogen receptor engagement activates endothelial nitric oxide synthase via the PI3-kinase-Akt pathway in human endothelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151626

8 July 2018

Interaction of oestrogen receptor with the regulatory subunit of phosphatidylinositol-3-OH kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151626

8 July 2018

Neuroprotection mediated by changes in the endothelial actin cytoskeleton.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151626

8 July 2018

Advances in the vascular pathophysiology of ischemic stroke

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151626

8 July 2018

Endothelial nitric oxide synthase-dependent cerebral blood flow augmentation by L-arginine after chronic statin treatment

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151626

8 July 2018

The glucocorticoid receptor mediates a survival signal in human mammary epithelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151626

8 July 2018

Akt promotes survival of cardiomyocytes in vitro and protects against ischemia-reperfusion injury in mouse heart.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151626

8 July 2018

Down-regulation of the expression of endothelial NO synthase is likely to contribute to glucocorticoid-mediated hypertension

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151626

8 July 2018

Activation of nitric oxide synthase in endothelial cells by Akt-dependent phosphorylation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151626

8 July 2018

Regulation of endothelium-derived nitric oxide production by the protein kinase Akt

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151626

8 July 2018

Serum and glucocorticoid-inducible kinase (SGK) is a target of the PI 3-kinase-stimulated signaling pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151626

8 July 2018

The role of phosphoinositide 3-kinase lipid products in cell function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151626

8 July 2018

Estrogen receptor alpha mediates the nongenomic activation of endothelial nitric oxide synthase by estrogen

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151626

8 July 2018

Stroke protection by 3-hydroxy-3-methylglutaryl (HMG)-CoA reductase inhibitors mediated by endothelial nitric oxide synthase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151626

8 July 2018

DNA binding of the glucocorticoid receptor is not essential for survival

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151626

8 July 2018

Nitric oxide production contributes to the angiogenic properties of vascular endothelial growth factor in human endothelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151626

8 July 2018

Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151626

8 July 2018

Synthetic glucocorticoids that dissociate transactivation and AP-1 transrepression exhibit antiinflammatory activity in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151626

8 July 2018

Bright and dark sides of nitric oxide in ischemic brain injury

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151626

8 July 2018

Enlarged infarcts in endothelial nitric oxide synthase knockout mice are attenuated by nitro-L-arginine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151626

8 July 2018

Steroid hormone receptors: many actors in search of a plot

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151626

8 July 2018

Efficacious experimental stroke treatment with high-dose methylprednisolone

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151626

8 July 2018

A distinct modulating domain in glucocorticoid receptor monomers in the repression of activity of the transcription factor AP-1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151626

8 July 2018

Blood flow-dependent functional recovery in a rat model of focal cerebral ischemia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151626

8 July 2018

Reduction of focal cerebral ischemic damage by delayed treatment with nitric oxide donors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151626

8 July 2018

Protein kinase B (c-Akt) in phosphatidylinositol-3-OH kinase signal transduction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151626

8 July 2018

Targeted disruption of the glucocorticoid receptor gene blocks adrenergic chromaffin cell development and severely retards lung maturation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151626

8 July 2018

Hypertension in mice lacking the gene for endothelial nitric oxide synthase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151626

8 July 2018

L-arginine infusion promotes nitric oxide-dependent vasodilation, increases regional cerebral blood flow, and reduces infarction volume in the rat.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151626

8 July 2018

Reduction of Experimental Myocardial Infarct Size by Corticosteroid Administration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151626

8 July 2018

Double-blind study of the effects of dexamethasone on acute stroke

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151626

8 July 2018

Glucocorticoids potentiate ischemic injury to neurons: therapeutic implications.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151626

8 July 2018

High dose steroid treatment in cerebral infarction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151626

8 July 2018

Primary structure and expression of a functional human glucocorticoid receptor cDNA

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151626

8 July 2018

A corticosteroid receptor in neuronal membranes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151626

8 July 2018

Formation of phosphatidylinositol 3-phosphate by isomerization from phosphatidylinositol 4-phosphate

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151626

8 July 2018

Studies on the anti-allergic mechanism of glucocorticoids in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151626

8 July 2018

A mechanism for the antiinflammatory effects of corticosteroids: the glucocorticoid receptor regulates leukocyte adhesion to endothelial cells and expression of endothelial-leukocyte adhesion molecule 1 and intercellular adhesion molecule 1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151626

8 July 2018

Steroid Therapy in Acute Cerebral Infarction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151626

8 July 2018

Contractile properties of small arterial resistance vessels in spontaneously hypertensive and normotensive rats.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151626

8 July 2018

Corticosteroids in ischemic stroke

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151626

8 July 2018

Dexamethasone in acute stroke.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151626

8 July 2018

Endothelial nitric oxide synthase pathophysiology after nonocclusive common carotid artery thrombosis in rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151626

26 October 2018

Are the effects of T3 on resting metabolic rate in euthyroid rats entirely caused by T3 itself?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151626

26 October 2018

MK 801 and dexamethasone reduce both tumor necrosis factor levels and infarct volume after focal cerebral ischemia in the rat brain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151626

26 October 2018

A semiautomated method for measuring brain infarct volume.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151626

26 October 2018

A Randomized, Controlled Trial of Methylprednisolone or Naloxone in the Treatment of Acute Spinal-Cord Injury

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151626

9 December 2018

Effects of Cerebral Ischemia in Mice Deficient in Neuronal Nitric Oxide Synthase

1 reference

https://pubmed.ncbi.nlm.nih.gov/12464678

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of endothelial nitric oxide synthase in the ischemic penumbra: relationship to expression of neuronal nitric oxide synthase and vascular endothelial growth factor

1 reference

https://pubmed.ncbi.nlm.nih.gov/12464678

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dexamethasone as Treatment in Cerebrovascular Disease. 2. A Controlled Study in Acute Cerebral Infarction

1 reference

https://pubmed.ncbi.nlm.nih.gov/12464678

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Efficacy of Methylprednisolone in Acute Spinal Cord Injury

1 reference

https://pubmed.ncbi.nlm.nih.gov/12464678

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Stimulation of the phosphoinositide signalling system as a possible mechanism for glucocorticoid action in blood pressure control

1 reference

https://pubmed.ncbi.nlm.nih.gov/12464678

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1172/JCI0215481

1 reference

Europe PubMed Central

PubMed publication ID

4 August 2017

10.1172/JCI15481

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12464678%20AND%20SRC:MED&resulttype=core&format=json

15 December 2019

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12464678%20AND%20SRC:MED&resulttype=core&format=json

15 December 2019

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12464678%20AND%20SRC:MED&resulttype=core&format=json

15 December 2019

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