(Q34829498)

4 August 2017

title

A CTRP5 gene S163R mutation knock-in mouse model for late-onset retinal degeneration (English)

1 reference

4 August 2017

1 reference

Venkata R M Chavali

1

1 reference

4 August 2017

Naheed W Khan

2

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4 August 2017

Catherine A Cukras

3

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4 August 2017

Dirk-Uwe Bartsch

4

1 reference

4 August 2017

Monica M Jablonski

5

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4 August 2017

Radha Ayyagari

6

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4 August 2017

publication date

24 February 2011

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4 August 2017

published in

Human Molecular Genetics

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4 August 2017

volume

20

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4 August 2017

issue

10

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4 August 2017

page(s)

2000-2014

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Virtual microscopy, data management and image analysis in Aperio ScanScope system

4 August 2017

cites work

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8 July 2018

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CTRP5 is a membrane-associated and secretory protein in the RPE and ciliary body and the S163R mutation of CTRP5 impairs its secretion

8 July 2018

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8 July 2018

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8 July 2018

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In vivo confocal imaging of the retina in animal models using scanning laser ophthalmoscopy

8 July 2018

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Late-onset macular degeneration and long anterior lens zonules result from a CTRP5 gene mutation.

8 July 2018

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Extreme hyperopia is the result of null mutations in MFRP, which encodes a Frizzled-related protein

8 July 2018

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Lipofuscin accumulation, abnormal electrophysiology, and photoreceptor degeneration in mutant ELOVL4 transgenic mice: a model for macular degeneration

8 July 2018

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8 July 2018

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8 July 2018

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An animal model of age-related macular degeneration in senescent Ccl-2- or Ccr-2-deficient mice

8 July 2018

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Mutation in a short-chain collagen gene, CTRP5, results in extracellular deposit formation in late-onset retinal degeneration: a genetic model for age-related macular degeneration

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3080610

Oxidative stress-induced mitochondrial DNA damage in human retinal pigment epithelial cells: a possible mechanism for RPE aging and age-related macular degeneration

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3080610

Aberrant accumulation of EFEMP1 underlies drusen formation in Malattia Leventinese and age-related macular degeneration

8 July 2018

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Mfrp, a gene encoding a frizzled related protein, is mutated in the mouse retinal degeneration 6

8 July 2018

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Dark adaptation in age-related macular degeneration: relationship to the fellow eye.

8 July 2018

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Symptomatic abnormalities of dark adaptation in patients with EFEMP1 retinal dystrophy (Malattia Leventinese/Doyne honeycomb retinal dystrophy).

8 July 2018

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An integrated hypothesis that considers drusen as biomarkers of immune-mediated processes at the RPE-Bruch's membrane interface in aging and age-related macular degeneration

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3080610

The role of the retinal pigment epithelium: topographical variation and ageing changes

8 July 2018

1 reference

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Basal linear deposit and large drusen are specific for early age-related maculopathy

8 July 2018

1 reference

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Abnormalities in monocyte recruitment and cytokine expression in monocyte chemoattractant protein 1-deficient mice

8 July 2018

1 reference

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Impaired monocyte migration and reduced type 1 (Th1) cytokine responses in C-C chemokine receptor 2 knockout mice

8 July 2018

1 reference

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Severe reduction in leukocyte adhesion and monocyte extravasation in mice deficient in CC chemokine receptor 2.

8 July 2018

1 reference

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Pathology of hereditary retinal degeneration associated with hypobetalipoproteinemia

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3080610

Dominantly inherited drusen represent more than one disorder: a historical review

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3080610

Distribution of fundus autofluorescence with a scanning laser ophthalmoscope

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3080610

Night blindness in Sorsby's fundus dystrophy reversed by vitamin A

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3080610

Retinal pigment epithelial lipofuscin and melanin and choroidal melanin in human eyes

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3080610

Dark-adapted luminance-response functions with skin and corneal electrodes.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3080610

Long anterior zonules and pigment dispersion.

8 July 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR080

The role of aging, high fat diet and blue light exposure in an experimental mouse model for basal laminar deposit formation

21 January 2018

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https://api.crossref.org/works/10.1093%2FHMG%2FDDR080

The murine cone photoreceptor: a single cone type expresses both S and M opsins with retinal spatial patterning

21 January 2018

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https://api.crossref.org/works/10.1093%2FHMG%2FDDR080

Structure-function analysis of rods and cones in juvenile, adult, and aged C57bl/6 and Balb/c mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR080

Formation and progression of sub-retinal pigment epithelium deposits in Efemp1 mutation knock-in mice: a model for the early pathogenic course of macular degeneration.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR080

Retinal pigment epithelium cell damage by A2-E and its photo-derivatives.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3080610

A mouse model for Sorsby fundus dystrophy.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3080610

Phenotypic marker for early disease detection in dominant late-onset retinal degeneration.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3080610

P23H rhodopsin transgenic rat: correlation of retinal function with histopathology.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3080610

Accumulation of lipofuscin within retinal pigment epithelial cells results in enhanced sensitivity to photo-oxidation.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3080610

The R345W mutation in EFEMP1 is pathogenic and causes AMD-like deposits in mice

26 October 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR080

Dominant late-onset retinal degeneration with regional variation of sub-retinal pigment epithelium deposits, retinal function, and photoreceptor degeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR080

The relationships of age changes in retinal pigment epithelium and Bruch's membrane

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3080610

Sub-retinal pigment epithelial deposits in a dominant late-onset retinal degeneration

9 December 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3080610

The topography and age relationship of lipofuscin concentration in the retinal pigment epithelium

9 December 2018

1 reference

12 December 2020

Lipofuscin of human retinal pigment epithelium

1 reference

12 December 2020

Extensive subretinal pigment epithelial deposit in two brothers suffering from dominant retinitis pigmentosa. A histopathological study

1 reference

12 December 2020

Abnormal dark adaptation and rhodopsin kinetics in Sorsby's fundus dystrophy

1 reference

12 December 2020

Autosomal dominant hemorrhagic macular dystrophy not associated with the TIMP3 gene

1 reference

12 December 2020

Photodamage to human RPE cells by A2-E, a retinoid component of lipofuscin

1 reference

12 December 2020

Diffuse cellular and fibrosing interstitial pneumonitis with desquamative interstitial pneumonitis-like features associated with myeloid neoplasia

1 reference

12 December 2020

The spatio-temporal pattern of photoreceptor degeneration in the aged rd/rd mouse retina

1 reference

12 December 2020

Morphologic changes in age-related maculopathy

1 reference

12 December 2020

Fundus autofluorescence in age-related macular disease imaged with a laser scanning ophthalmoscope

1 reference

12 December 2020

Identifiers

DOI

10.1093/HMG/DDR080

1 reference

4 August 2017

1 reference

4 August 2017

1 reference