(Q34846428)

4 August 2017

Indoxyl sulfate down-regulates SLCO4C1 transporter through up-regulation of GATA3. (English)

1 reference

4 August 2017

17

Sadayoshi Ito

1 reference

4 August 2017

Yasutoshi Akiyama

1

1 reference

4 August 2017

Koichi Kikuchi

2

1 reference

4 August 2017

Daisuke Saigusa

3

1 reference

4 August 2017

Takehiro Suzuki

4

1 reference

4 August 2017

Yoichi Takeuchi

5

1 reference

4 August 2017

Eikan Mishima

6

1 reference

4 August 2017

Yasuaki Yamamoto

7

1 reference

4 August 2017

Ayako Ishida

8

1 reference

4 August 2017

Daiki Sugawara

9

1 reference

4 August 2017

Daisuke Jinno

10

1 reference

4 August 2017

Hisato Shima

11

1 reference

4 August 2017

Takafumi Toyohara

12

1 reference

4 August 2017

Chitose Suzuki

13

1 reference

4 August 2017

Tomokazu Souma

14

1 reference

4 August 2017

Takashi Moriguchi

15

1 reference

4 August 2017

Yoshihisa Tomioka

16

1 reference

4 August 2017

Takaaki Abe

18

1 reference

4 August 2017

language of work or name

English

0 references

publication date

9 July 2013

1 reference

4 August 2017

1 reference

4 August 2017

8

1 reference

4 August 2017

e66518

1 reference

4 August 2017

7

1 reference

Creative Commons Attribution 4.0 International

4 August 2017

start time

9 July 2013

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

Normal and pathologic concentrations of uremic toxins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3706553

Current understanding of drug disposition in kidney disease

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3706553

An update on protein-bound uremic retention solutes

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3706553

Inflammation-mediated changes in drug transporter expression/activity: implications for therapeutic drug response

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3706553

PGC-1α promotes recovery after acute kidney injury during systemic inflammation in mice

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3706553

NF-κB plays an important role in indoxyl sulfate-induced cellular senescence, fibrotic gene expression, and inhibition of proliferation in proximal tubular cells

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3706553

Transcriptional regulation of organic anion transporting polypeptide SLCO4C1 as a new therapeutic modality to prevent chronic kidney disease.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3706553

The antioxidant EPC-K1 attenuates renal ischemia-reperfusion injury in a rat model

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3706553

Update on the pharmacokinetics and redox properties of protein-bound uremic toxins

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3706553

Effects of chronic renal failure on kidney drug transporters and cytochrome P450 in rats

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3706553

Uremic toxins inhibit transport by breast cancer resistance protein and multidrug resistance protein 4 at clinically relevant concentrations.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3706553

Guanidino compounds as cause of cardiovascular damage in chronic kidney disease: an in vitro evaluation.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3706553

Indoxyl sulfate-induced endothelial dysfunction in patients with chronic kidney disease via an induction of oxidative stress

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3706553

Regulation of drug metabolism and transporters

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3706553

SLCO4C1 transporter eliminates uremic toxins and attenuates hypertension and renal inflammation

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3706553

Guanidino compounds as uremic (neuro)toxins

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3706553

New insights into uremic toxicity

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3706553

Emerging evidence of the impact of kidney disease on drug metabolism and transport

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3706553

A bench to bedside view of uremic toxins

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3706553

Roles of organic anion transporters in the progression of chronic renal failure

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3706553

Effects of renal failure on drug transport and metabolism

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3706553

Regulation of GATA gene expression during vertebrate development

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3706553

The organic anion transporter (OATP) family.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3706553

Chronic kidney disease and the risks of death, cardiovascular events, and hospitalization

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3706553

Isolation and characterization of a digoxin transporter and its rat homologue expressed in the kidney

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3706553

A GATA-specific inhibitor (K-7174) rescues anemia induced by IL-1beta, TNF-alpha, or L-NMMA.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3706553

The GATA family (vertebrates and invertebrates).

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3706553

Gata3 loss leads to embryonic lethality due to noradrenaline deficiency of the sympathetic nervous system

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3706553

Immunohistochemical distribution and functional characterization of an organic anion transporting polypeptide 2 (oatp2).

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3706553

Rescue of the embryonic lethal hematopoietic defect reveals a critical role for GATA-2 in urogenital development

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3706553

Effects of chronic renal failure on brain drug transporters in rats.

8 July 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0066518

Metabolomic profiling of uremic solutes in CKD patients.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0066518

Simultaneous determination of guanidinosuccinic acid and guanidinoacetic acid in urine using high performance liquid chromatography/tandem mass spectrometry

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0066518

Repression via the GATA box is essential for tissue-specific erythropoietin gene expression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0066518

Down-regulation of rat organic cation transporter rOCT2 by 5/6 nephrectomy

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0066518

The low nanomolar levels of N G-monomethylarginine in serum and urine of patients with chronic renal insufficiency are not significantly different from control levels

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0066518

Indoxyl sulfate induces skeletal resistance to parathyroid hormone in cultured osteoblastic cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0066518

Indoxyl sulfate upregulates expression of ICAM-1 and MCP-1 by oxidative stress-induced NF-kappaB activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0066518

In vitro study of the potential role of guanidines in leukocyte functions related to atherogenesis and infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0066518

Evidence that guanidines and some related compounds cause haemolysis in chronic uraemia

21 January 2018

1 reference

12 December 2020

Role of indoxyl sulfate in the progression of chronic kidney disease and cardiovascular disease: experimental and clinical effects of oral sorbent AST-120

1 reference

12 December 2020

N(G)-monomethyl-L-arginine inhibits erythropoietin gene expression by stimulating GATA-2

1 reference

12 December 2020

Effects of oral adsorbent on gene expression profile in uremic rat kidney: cDNA array analysis

1 reference

12 December 2020

Drug binding in human serum albumin as assayed by diafiltration and fluorimetry

1 reference

12 December 2020

Indoxyl sulfate, a circulating uremic toxin, stimulates the progression of glomerular sclerosis

1 reference

12 December 2020

Indoxyl sulfate increases the gene expressions of TGF-beta 1, TIMP-1 and pro-alpha 1(I) collagen in uremic rat kidneys

1 reference

12 December 2020

Accumulation of indoxyl sulfate in OAT1/3-positive tubular cells in kidneys of patients with chronic renal failure

1 reference

12 December 2020

10.1371/JOURNAL.PONE.0066518

Identifiers

DOI

1 reference

4 August 2017

0 references

1 reference

4 August 2017

1 reference