(Q34849521)

4 August 2017

title

Evaluation of peptide-aldehyde inhibitors using R188I mutant of SARS 3CL protease as a proteolysis-resistant mutant (English)

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4 August 2017

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Kenichi Akaji

1

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4 August 2017

Hiroyuki Konno

2

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4 August 2017

Mari Onozuka

3

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4 August 2017

Ayumi Makino

4

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4 August 2017

Hiroyuki Saito

5

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4 August 2017

Kazuto Nosaka

6

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4 August 2017

language of work or name

English

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publication date

26 September 2008

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Bioorganic & Medicinal Chemistry

4 August 2017

published in

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4 August 2017

volume

16

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4 August 2017

issue

21

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4 August 2017

page(s)

9400-9408

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3C-like proteinase from SARS coronavirus catalyzes substrate hydrolysis by a general base mechanism

4 August 2017

cites work

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12 December 2020

A new lead for nonpeptidic active-site-directed inhibitors of the severe acute respiratory syndrome coronavirus main protease discovered by a combination of screening and docking methods

1 reference

12 December 2020

Identification of a novel coronavirus in patients with severe acute respiratory syndrome

1 reference

12 December 2020

Synthesis, crystal structure, structure-activity relationships, and antiviral activity of a potent SARS coronavirus 3CL protease inhibitor

1 reference

12 December 2020

Identification of novel inhibitors of the SARS coronavirus main protease 3CLpro.

1 reference

12 December 2020

Discovery of potent anilide inhibitors against the severe acute respiratory syndrome 3CL protease

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12 December 2020

Mechanisms and enzymes involved in SARS coronavirus genome expression

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12 December 2020

The crystal structures of severe acute respiratory syndrome virus main protease and its complex with an inhibitor

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12 December 2020

Structure of coronavirus main proteinase reveals combination of a chymotrypsin fold with an extra alpha-helical domain

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12 December 2020

An efficient method for the synthesis of peptide aldehyde libraries employed in the discovery of reversible SARS coronavirus main protease (SARS-CoV Mpro) inhibitors

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12 December 2020

Mechanism of the maturation process of SARS-CoV 3CL protease

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12 December 2020

The Genome sequence of the SARS-associated coronavirus

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12 December 2020

Crystal structures of the main peptidase from the SARS coronavirus inhibited by a substrate-like aza-peptide epoxide.

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12 December 2020

Enzymatic inverse PCR: a restriction site independent, single-fragment method for high-efficiency, site-directed mutagenesis

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12 December 2020

A novel coronavirus associated with severe acute respiratory syndrome

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12 December 2020

Sequence from picomole quantities of proteins electroblotted onto polyvinylidene difluoride membranes

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12 December 2020

Biosynthesis, Purification, and Substrate Specificity of Severe Acute Respiratory Syndrome Coronavirus 3C-like Proteinase

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12 December 2020

A major outbreak of severe acute respiratory syndrome in Hong Kong

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12 December 2020

Synthesis and evaluation of isatin derivatives as effective SARS coronavirus 3CL protease inhibitors

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12 December 2020

Quaternary structure of the severe acute respiratory syndrome (SARS) coronavirus main protease

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12 December 2020

Coronavirus main proteinase (3CLpro) structure: basis for design of anti-SARS drugs

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12 December 2020

Design and synthesis of peptidomimetic severe acute respiratory syndrome chymotrypsin-like protease inhibitors

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12 December 2020

Inhibition of the severe acute respiratory syndrome 3CL protease by peptidomimetic alpha,beta-unsaturated esters

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12 December 2020

Characterization of a novel coronavirus associated with severe acute respiratory syndrome

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12 December 2020

Structure-based design, synthesis, and biological evaluation of peptidomimetic SARS-CoV 3CLpro inhibitors

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12 December 2020

Synthesis and evaluation of keto-glutamine analogues as potent inhibitors of severe acute respiratory syndrome 3CLpro

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12 December 2020

Synthesis of glutamic acid and glutamine peptides possessing a trifluoromethyl ketone group as SARS-CoV 3CL protease inhibitors

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12 December 2020

10.1016/J.BMC.2008.09.057

Identifiers

DOI

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4 August 2017

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