(Q46580414)

23 December 2017

title

Inhibition of the severe acute respiratory syndrome 3CL protease by peptidomimetic alpha,beta-unsaturated esters (English)

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23 December 2017

author

Jim-Min Fang

2

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23 December 2017

Chi-Huey Wong

10

object named as

Chi-Huey Wong

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23 December 2017

author name string

Jiun-Jie Shie

1

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23 December 2017

Tun-Hsun Kuo

3

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23 December 2017

Chih-Jung Kuo

4

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23 December 2017

Po-Huang Liang

5

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23 December 2017

Hung-Jyun Huang

6

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23 December 2017

Yin-Ta Wu

7

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23 December 2017

Jia-Tsrong Jan

8

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23 December 2017

Yih-Shyun E Cheng

9

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23 December 2017

language of work or name

English

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publication date

1 September 2005

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23 December 2017

Bioorganic & Medicinal Chemistry

published in

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23 December 2017

volume

13

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23 December 2017

issue

17

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23 December 2017

page(s)

5240-5252

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23 December 2017

A novel coronavirus associated with severe acute respiratory syndrome

cites work

1 reference

12 December 2020

Synthesis and biological evaluation of 3-heterocyclyl-7,8,9,10-tetrahydro-(7,10-ethano)-1,2,4-triazolo[3,4-a]phthalazines and analogues as subtype-selective inverse agonists for the GABA(A)alpha5 benzodiazepine binding site.

1 reference

12 December 2020

Picornavirus protein processing--enzymes, substrates, and genetic regulation

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12 December 2020

Identification of novel inhibitors of the SARS coronavirus main protease 3CLpro.

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12 December 2020

Coronavirus main proteinase (3CLpro) structure: basis for design of anti-SARS drugs

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12 December 2020

The crystal structures of severe acute respiratory syndrome virus main protease and its complex with an inhibitor

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12 December 2020

Characterization of SARS main protease and inhibitor assay using a fluorogenic substrate

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12 December 2020

Binding mechanism of coronavirus main proteinase with ligands and its implication to drug design against SARS.

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12 December 2020

3C-like proteinase from SARS coronavirus catalyzes substrate hydrolysis by a general base mechanism

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12 December 2020

Identification of novel small-molecule inhibitors of severe acute respiratory syndrome-associated coronavirus by chemical genetics.

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12 December 2020

Comparative full-length genome sequence analysis of 14 SARS coronavirus isolates and common mutations associated with putative origins of infection

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12 December 2020

Biosynthesis, Purification, and Substrate Specificity of Severe Acute Respiratory Syndrome Coronavirus 3C-like Proteinase

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12 December 2020

In vitro antiviral activity of AG7088, a potent inhibitor of human rhinovirus 3C protease

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12 December 2020

Use of an aqueous soluble tetrazolium/formazan assay to measure viability and proliferation of lymphokine-dependent cell lines

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12 December 2020

Viral proteinases: weakness in strength

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12 December 2020

High-throughput screening identifies inhibitors of the SARS coronavirus main proteinase

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12 December 2020

Rapid diversity-oriented synthesis in microtiter plates for in situ screening: discovery of potent and selective alpha-fucosidase inhibitors.

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12 December 2020

Small molecules targeting severe acute respiratory syndrome human coronavirus

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12 December 2020

Identification of a novel coronavirus in patients with severe acute respiratory syndrome

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12 December 2020

Polyprotein cleavage mechanism of SARS CoV Mpro and chemical modification of the octapeptide

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12 December 2020

Human immunodeficiency virus proteinase dimer as component of the viral polyprotein prevents particle assembly and viral infectivity

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12 December 2020

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12 December 2020

Discovery of picomolar slow tight-binding inhibitors of alpha-fucosidase

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12 December 2020

Virtual screening for SARS-CoV protease based on KZ7088 pharmacophore points

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12 December 2020

Structure-based design, synthesis, and biological evaluation of irreversible human rhinovirus 3C protease inhibitors. 4. Incorporation of P1 lactam moieties as L-glutamine replacements

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12 December 2020

Evaluation of metal-conjugated compounds as inhibitors of 3CL protease of SARS-CoV.

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12 December 2020

Characterization of a novel coronavirus associated with severe acute respiratory syndrome

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12 December 2020

Synthesis and evaluation of keto-glutamine analogues as potent inhibitors of severe acute respiratory syndrome 3CLpro

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12 December 2020

Structure-assisted design of mechanism-based irreversible inhibitors of human rhinovirus 3C protease with potent antiviral activity against multiple rhinovirus serotypes

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12 December 2020

The Genome sequence of the SARS-associated coronavirus

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12 December 2020

Active human immunodeficiency virus protease is required for viral infectivity

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12 December 2020

Coronavirus as a possible cause of severe acute respiratory syndrome

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12 December 2020

10.1016/J.BMC.2005.05.065

Identifiers

DOI

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23 December 2017

PubMed ID

15994085

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23 December 2017