(Q34850583)

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Embryonic stem cell-derived motoneurons provide a highly sensitive cell culture model for botulinum neurotoxin studies, with implications for high-throughput drug discovery

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Europe PubMed Central

PubMed publication ID

4 August 2017

Embryonic stem cell-derived motoneurons provide a highly sensitive cell culture model for botulinum neurotoxin studies, with implications for high-throughput drug discovery (English)

1 reference

Europe PubMed Central

PubMed publication ID

4 August 2017

1 reference

based on heuristic

inferred from title

10

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Sina Bavari

1 reference

Europe PubMed Central

PubMed publication ID

4 August 2017

object named as

Erkan Kiris

1

0 references

Lino Tessarollo

9

object named as

Lino Tessarollo

1 reference

Europe PubMed Central

PubMed publication ID

4 August 2017

author name string

Jonathan E Nuss

2

1 reference

Europe PubMed Central

PubMed publication ID

4 August 2017

James C Burnett

3

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Europe PubMed Central

PubMed publication ID

4 August 2017

Krishna P Kota

4

1 reference

Europe PubMed Central

PubMed publication ID

4 August 2017

Dawn C Koh

5

1 reference

Europe PubMed Central

PubMed publication ID

4 August 2017

Laura M Wanner

6

1 reference

Europe PubMed Central

PubMed publication ID

4 August 2017

Edna Torres-Melendez

7

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Europe PubMed Central

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4 August 2017

Rick Gussio

8

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Europe PubMed Central

PubMed publication ID

4 August 2017

publication date

19 January 2011

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Europe PubMed Central

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4 August 2017

Stem Cell Research

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Europe PubMed Central

PubMed publication ID

4 August 2017

6

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Europe PubMed Central

PubMed publication ID

4 August 2017

3

1 reference

Europe PubMed Central

PubMed publication ID

4 August 2017

195-205

1 reference

Europe PubMed Central

PubMed publication ID

4 August 2017

Development of high-content imaging assays for lethal viral pathogens.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3081902

8 July 2018

Gaining ground: assays for therapeutics against botulinum neurotoxin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3081902

8 July 2018

p75 neurotrophin receptor is involved in proliferation of undifferentiated mouse embryonic stem cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3081902

8 July 2018

Engineering botulinum neurotoxin to extend therapeutic intervention.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3081902

8 July 2018

Development of future indications for BOTOX.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3081902

8 July 2018

Neuro-exocytosis: botulinum toxins as inhibitory probes and versatile therapeutics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3081902

8 July 2018

Neuritogenic actions of botulinum neurotoxin A on cultured motor neurons

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3081902

8 July 2018

Association of botulinum neurotoxins with synaptic vesicle protein complexes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3081902

8 July 2018

A reappraisal of the central effects of botulinum neurotoxin type A: by what mechanism?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3081902

8 July 2018

Novel chimeras of botulinum neurotoxins A and E unveil contributions from the binding, translocation, and protease domains to their functional characteristics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3081902

8 July 2018

Directed differentiation of ventral spinal progenitors and motor neurons from human embryonic stem cells by small molecules

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3081902

8 July 2018

A neuronal cell-based botulinum neurotoxin assay for highly sensitive and specific detection of neutralizing serum antibodies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3081902

8 July 2018

Pro-NGF secreted by astrocytes promotes motor neuron cell death

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3081902

8 July 2018

Neurotrophin and Trk-mediated signaling in the neuromuscular system

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3081902

8 July 2018

Presynaptic enzymatic neurotoxins.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3081902

8 July 2018

Re-engineering the target specificity of Clostridial neurotoxins - a route to novel therapeutics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3081902

8 July 2018

The synaptic vesicle protein 2C mediates the uptake of botulinum neurotoxin A into phrenic nerves

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3081902

8 July 2018

SV2 is the protein receptor for botulinum neurotoxin A.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3081902

8 July 2018

Analyzing a bioterror attack on the food supply: the case of botulinum toxin in milk

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3081902

8 July 2018

Internalization and mechanism of action of clostridial toxins in neurons

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3081902

8 July 2018

Botulinal neurotoxins: revival of an old killer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3081902

8 July 2018

The evolving field of biodefence: therapeutic developments and diagnostics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3081902

8 July 2018

A molecular basis underlying differences in the toxicity of botulinum serotypes A and E.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3081902

8 July 2018

Using fluorescent sensors to detect botulinum neurotoxin activity in vitro and in living cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3081902

8 July 2018

Functional properties of motoneurons derived from mouse embryonic stem cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3081902

8 July 2018

Botulinum toxin in clinical practice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3081902

8 July 2018

Axonal growth of embryonic stem cell-derived motoneurons in vitro and in motoneuron-injured adult rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3081902

8 July 2018

Identification of the major steps in botulinum toxin action

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3081902

8 July 2018

Directed differentiation of embryonic stem cells into motor neurons

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3081902

8 July 2018

Botulinum Toxin as a Biological Weapon: Medical and Public Health Management

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3081902

8 July 2018

Cleavage of SNAP-25 by botulinum toxin type A requires receptor-mediated endocytosis, pH-dependent translocation, and zinc

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3081902

8 July 2018

Botulinum neurotoxin A blocks synaptic vesicle exocytosis but not endocytosis at the nerve terminal

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3081902

8 July 2018

Botulinum toxin therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3081902

8 July 2018

Lectins from Triticum vulgaris and Limax flavus are universal antagonists of botulinum neurotoxin and tetanus toxin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3081902

8 July 2018

Neuroblastoma x spinal cord (NSC) hybrid cell lines resemble developing motor neurons

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3081902

8 July 2018

Development of cell-based assays to measure botulinum neurotoxin serotype A activity using cleavage-sensitive antibodies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3081902

26 October 2018

Persistence of botulinum toxin in patients' serum: Alaska, 1959-2007.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3081902

26 October 2018

Differentiation of mouse embryonic stem cells to spinal motor neurons

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3081902

26 October 2018

Primary cultures of embryonic chicken neurons for sensitive cell-based assay of botulinum neurotoxin: implications for therapeutic discovery.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3081902

26 October 2018

Motoneurons derived from embryonic stem cells express transcription factors and develop phenotypes characteristic of medial motor column neurons.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3081902

26 October 2018

Primary cell culture for evaluation of botulinum neurotoxin antagonists

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3081902

26 October 2018

Uptake of botulinum neurotoxin into cultured neurons.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3081902

26 October 2018

Inhibition of neurotransmitter release by peptides that mimic the N-terminal domain of SNAP-25.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3081902

26 October 2018

The role of the synaptic protein snap-25 in the potency of botulinum neurotoxin type A.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3081902

26 October 2018

Persistence of botulinum neurotoxin A demonstrated by sequential administration of serotypes A and E in rat EDL muscle

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3081902

26 October 2018

Botulinum neurotoxin A selectively cleaves the synaptic protein SNAP-25

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3081902

9 December 2018

SNARE motif and neurotoxins

1 reference

https://pubmed.ncbi.nlm.nih.gov/21353660

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Persistence of botulinum neurotoxin action in cultured spinal cord cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/21353660

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Most Poisonous Poison

1 reference

https://pubmed.ncbi.nlm.nih.gov/21353660

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Peptides that mimic the carboxy-terminal domain of SNAP-25 block acetylcholine release at an Aplysia synapse

1 reference

https://pubmed.ncbi.nlm.nih.gov/21353660

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Long-distance retrograde effects of botulinum neurotoxin A

1 reference

https://pubmed.ncbi.nlm.nih.gov/21353660

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Xenotransplantation of embryonic stem cell-derived motor neurons into the developing chick spinal cord

1 reference

https://pubmed.ncbi.nlm.nih.gov/21353660

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Isolation and enrichment of embryonic mouse motoneurons from the lumbar spinal cord of individual mouse embryos

1 reference

https://pubmed.ncbi.nlm.nih.gov/21353660

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Purification of embryonic rat motoneurons by panning on a monoclonal antibody to the low-affinity NGF receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/21353660

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of vacuolar adenosine triphosphatase antagonizes the effects of clostridial neurotoxins but not phospholipase A2 neurotoxins

1 reference

https://pubmed.ncbi.nlm.nih.gov/21353660

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1016/J.SCR.2011.01.002

1 reference

Europe PubMed Central

PubMed publication ID

4 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

4 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

4 August 2017

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