(Q34859485)

4 August 2017

title

Deficiency for the cysteine protease cathepsin L promotes tumor progression in mouse epidermis (English)

1 reference

4 August 2017

1 reference

J Dennemärker

1

1 reference

4 August 2017

T Lohmüller

2

1 reference

4 August 2017

J Mayerle

3

1 reference

4 August 2017

M Tacke

4

1 reference

4 August 2017

M M Lerch

5

1 reference

4 August 2017

L M Coussens

6

1 reference

4 August 2017

C Peters

7

1 reference

4 August 2017

T Reinheckel

8

1 reference

4 August 2017

language of work or name

English

0 references

publication date

21 December 2009

1 reference

4 August 2017

1 reference

4 August 2017

volume

29

1 reference

4 August 2017

issue

11

1 reference

4 August 2017

page(s)

1611-1621

1 reference

Design of selective Cathepsin inhibitors

4 August 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3082505

Beyond wavy hairs: the epidermal growth factor receptor and its ligands in skin biology and pathology

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3082505

Tumor microenvironment and angiogenesis

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3082505

Cathepsin L is responsible for processing and activation of proheparanase through multiple cleavages of a linker segment

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3082505

Matrix metalloproteinase-8 functions as a metastasis suppressor through modulation of tumor cell adhesion and invasion

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3082505

Increased expression and activity of nuclear cathepsin L in cancer cells suggests a novel mechanism of cell transformation.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3082505

The other side of MMPs: protective roles in tumor progression

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3082505

Loss of cathepsin L activity promotes claudin-1 overexpression and intestinal neoplasia

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3082505

Hyperactive Ras in developmental disorders and cancer

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3082505

Emerging roles of cysteine cathepsins in disease and their potential as drug targets.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3082505

PTPN11 is the first identified proto-oncogene that encodes a tyrosine phosphatase

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3082505

Cysteine cathepsins: multifunctional enzymes in cancer

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3082505

Cystatin M/E is a high affinity inhibitor of cathepsin V and cathepsin L by a reactive site that is distinct from the legumain-binding site. A novel clue for the role of cystatin M/E in epidermal cornification.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3082505

Distinct roles for cysteine cathepsin genes in multistage tumorigenesis

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3082505

Paradoxical roles of the immune system during cancer development

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3082505

The lysosomal cysteine protease cathepsin L regulates keratinocyte proliferation by control of growth factor recycling.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3082505

The human cysteine protease cathepsin V can compensate for murine cathepsin L in mouse epidermis and hair follicles.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3082505

Cathepsin L is required for endothelial progenitor cell-induced neovascularization

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3082505

Cysteine cathepsins in human cancer

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3082505

Friends or foes - bipolar effects of the tumour stroma in cancer

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3082505

Proteases, extracellular matrix, and cancer: a workshop of the path B study section

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3082505

Senescence-initiated reversal of drug resistance: specific role of cathepsin L.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3082505

Cathepsin V is involved in the degradation of invariant chain in human thymus and is overexpressed in myasthenia gravis

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3082505

The 'Shp'ing news: SH2 domain-containing tyrosine phosphatases in cell signaling

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3082505

Basement membranes: structure, assembly and role in tumour angiogenesis

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3082505

Analysis of proteins with caseinolytic activity in a human stratum corneum extract revealed a yet unidentified cysteine protease and identified the so-called "stratum corneum thiol protease" as cathepsin l2.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3082505

The lysosomal protease cathepsin L is an important regulator of keratinocyte and melanocyte differentiation during hair follicle morphogenesis and cycling

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3082505

Matrix Metalloproteinase Inhibitors and Cancer--Trials and Tribulations

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3082505

The microenvironment of the tumour-host interface

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3082505

MMP-9 supplied by bone marrow-derived cells contributes to skin carcinogenesis

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3082505

Cathepsin L deficiency as molecular defect of furless: hyperproliferation of keratinocytes and pertubation of hair follicle cycling

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3082505

Secreted cathepsin L generates endostatin from collagen XVIII

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3082505

Inflammatory mast cells up-regulate angiogenesis during squamous epithelial carcinogenesis

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3082505

Cancer invasion and tissue remodeling--cooperation of protease systems and cell types.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3082505

Genetic predisposition and parameters of malignant progression in K14-HPV16 transgenic mice.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3082505

Progressive squamous epithelial neoplasia in K14-human papillomavirus type 16 transgenic mice

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3082505

Loss of collagenase-2 confers increased skin tumor susceptibility to male mice.

8 July 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.466

De novo carcinogenesis promoted by chronic inflammation is B lymphocyte dependent

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.466

Adenovirus-mediated expression of antisense urokinase plasminogen activator receptor and antisense cathepsin B inhibits tumor growth, invasion, and angiogenesis in gliomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.466

Emerging roles of proteases in tumour suppression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.466

Extracellular cleavage of E-cadherin by leukocyte elastase during acute experimental pancreatitis in rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.466

Loss of responsiveness to IGF-I in cells with reduced cathepsin L expression levels.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.466

Tumor cell-derived and macrophage-derived cathepsin B promotes progression and lung metastasis of mammary cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.466

Signaling on the endocytic pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.466

Genomic Analysis Defines a Cancer-Specific Gene Expression Signature for Human Squamous Cell Carcinoma and Distinguishes Malignant Hyperproliferation from Benign Hyperplasia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.466

Reduced tumour cell proliferation and delayed development of high-grade mammary carcinomas in cathepsin B-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.466

Expression of the human Cathepsin L inhibitor hurpin in mice: skin alterations and increased carcinogenesis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.466

31 March 2020

Identifiers

DOI

10.1038/ONC.2009.466

1 reference

Dimensions Publication ID

4 August 2017

0 references

1 reference

4 August 2017

1 reference