(Q34864555)

5 August 2017

title

Accumulation of mitochondrial DNA deletions within dopaminergic neurons triggers neuroprotective mechanisms (English)

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5 August 2017

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Celine Perier

1

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5 August 2017

Andreas Bender

2

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5 August 2017

Elena García-Arumí

3

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5 August 2017

Ma Jesus Melià

4

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5 August 2017

Jordi Bové

5

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5 August 2017

Christoph Laub

6

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5 August 2017

Thomas Klopstock

7

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5 August 2017

Matthias Elstner

8

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5 August 2017

Ross B Mounsey

9

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5 August 2017

Peter Teismann

10

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5 August 2017

Tomas Prolla

11

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5 August 2017

Antoni L Andreu

12

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5 August 2017

Miquel Vila

13

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5 August 2017

language of work or name

English

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publication date

1 August 2013

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5 August 2017

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5 August 2017

volume

136

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5 August 2017

issue

Pt 8

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5 August 2017

page(s)

2369-2378

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High levels of mitochondrial DNA deletions in substantia nigra neurons in aging and Parkinson disease

5 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWT196

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Progressive parkinsonism in mice with respiratory-chain-deficient dopamine neurons

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Neuromelanin, neurotransmitter status and brainstem location determine the differential vulnerability of catecholaminergic neurons to mitochondrial DNA deletions

21 January 2018

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https://api.crossref.org/works/10.1093%2FBRAIN%2FAWT196

OPA1 controls apoptotic cristae remodeling independently from mitochondrial fusion

21 January 2018

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https://api.crossref.org/works/10.1093%2FBRAIN%2FAWT196

Mitochondrial DNA deletions are abundant and cause functional impairment in aged human substantia nigra neurons.

21 January 2018

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https://api.crossref.org/works/10.1093%2FBRAIN%2FAWT196

Abnormal Ca2+ dynamics in transgenic mice with neuron-specific mitochondrial DNA defects.

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https://api.crossref.org/works/10.1093%2FBRAIN%2FAWT196

Mitochondrial DNA mutations, oxidative stress, and apoptosis in mammalian aging

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https://api.crossref.org/works/10.1093%2FBRAIN%2FAWT196

Inducible nitric oxide synthase stimulates dopaminergic neurodegeneration in the MPTP model of Parkinson disease

21 January 2018

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https://api.crossref.org/works/10.1093%2FBRAIN%2FAWT196

Parkinsonism, premature menopause, and mitochondrial DNA polymerase gamma mutations: clinical and molecular genetic study.

21 January 2018

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https://api.crossref.org/works/10.1093%2FBRAIN%2FAWT196

Complex I deficiency primes Bax-dependent neuronal apoptosis through mitochondrial oxidative damage

21 January 2018

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https://api.crossref.org/works/10.1093%2FBRAIN%2FAWT196

Striatal dysfunctions associated with mitochondrial DNA damage in dopaminergic neurons in a mouse model of Parkinson's disease

21 January 2018

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https://api.crossref.org/works/10.1093%2FBRAIN%2FAWT196

MPTP as a mitochondrial neurotoxic model of Parkinson's disease

21 January 2018

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https://api.crossref.org/works/10.1093%2FBRAIN%2FAWT196

Optic atrophy 1 mediates mitochondria remodeling and dopaminergic neurodegeneration linked to complex I deficiency.

21 January 2018

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https://api.crossref.org/works/10.1093%2FBRAIN%2FAWT196

S100B is increased in Parkinson's disease and ablation protects against MPTP-induced toxicity through the RAGE and TNF-α pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWT196

D-beta-hydroxybutyrate rescues mitochondrial respiration and mitigates features of Parkinson disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWT196

Premature ageing in mice expressing defective mitochondrial DNA polymerase

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWT196

A mitochondrial paradigm of metabolic and degenerative diseases, aging, and cancer: a dawn for evolutionary medicine

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWT196

Mitochondrial DNA mutations activate the mitochondrial apoptotic pathway and cause dilated cardiomyopathy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWT196

21 January 2018

Identifiers

DOI

10.1093/BRAIN/AWT196

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5 August 2017

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