(Q35891901)

11 August 2017

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title

MPTP as a mitochondrial neurotoxic model of Parkinson's disease (English)

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11 August 2017

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1

Serge Przedborski

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11 August 2017

Kim Tieu

2

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11 August 2017

Celine Perier

series ordinal

3

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11 August 2017

Miquel Vila

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4

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11 August 2017

publication date

1 August 2004

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Journal of Bioenergetics and Biomembranes

11 August 2017

published in

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11 August 2017

volume

36

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11 August 2017

issue

4

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11 August 2017

page(s)

375-379

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Rapid ATP loss caused by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in mouse brain

11 August 2017

cites work

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12 December 2020

Uptake and accumulation of 1-methyl-4-phenylpyridinium by rat liver mitochondria measured using an ion-selective electrode

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12 December 2020

Effects of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine and 1-methyl-4-phenylpyridinium ion on ATP levels of mouse brain synaptosomes.

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12 December 2020

Biochemical events in the development of parkinsonism induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine

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12 December 2020

D-beta-hydroxybutyrate rescues mitochondrial respiration and mitigates features of Parkinson disease

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12 December 2020

The inhibition site of MPP+, the neurotoxic bioactivation product of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine is near the Q-binding site of NADH dehydrogenase

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12 December 2020

Specificity of pyridinium inhibitors of the ubiquinone reduction sites in mitochondrial complex I

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12 December 2020

Some features of the nigrostriatal dopaminergic neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) in the mouse

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12 December 2020

Studies on the molecular mechanism of bioactivation of the selective nigrostriatal toxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine.

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12 December 2020

Energy-dependent uptake of N-methyl-4-phenylpyridinium, the neurotoxic metabolite of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine, by mitochondria

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12 December 2020

1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) and 1-methyl-4-phenylpyridine (MPP+) cause rapid ATP depletion in isolated hepatocytes

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12 December 2020

The 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model: a tool to explore the pathogenesis of Parkinson's disease

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12 December 2020

Studies on the 1-methyl-4-phenyl-2,3-dihydropyridinium species 2,3-MPDP+, the monoamine oxidase catalyzed oxidation product of the nigrostriatal toxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP).

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12 December 2020

Energy-driven uptake of N-methyl-4-phenylpyridine by brain mitochondria mediates the neurotoxicity of MPTP.

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12 December 2020

1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) and free radicals in vitro

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12 December 2020

Characterization of the inhibitory mechanism of 1-methyl-4-phenylpyridinium and 4-phenylpyridine analogs in inner membrane preparations.

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12 December 2020

Relation of superoxide generation and lipid peroxidation to the inhibition of NADH-Q oxidoreductase by rotenone, piericidin A, and MPP+

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12 December 2020

Membrane potential and surface potential in mitochondria: uptake and binding of lipophilic cations.

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12 December 2020

Enhancement by tetraphenylboron of inhibition of mitochondrial respiration induced by 1-methyl-4-phenylpyridinium ion (MPP(+))

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12 December 2020

Effects of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine and 1-methyl-4-phenylpyridinium ion on activities of the enzymes in the electron transport system in mouse brain

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12 December 2020

Entry of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine into the rat brain

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12 December 2020

MPTP: current concepts and controversies

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12 December 2020

Interaction of 1-methyl-4-phenylpyridinium ion (MPP+) and its analogs with the rotenone/piericidin binding site of NADH dehydrogenase.

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12 December 2020

NADH-quinone oxidoreductase: PSST subunit couples electron transfer from iron-sulfur cluster N2 to quinone

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12 December 2020

Time course and morphology of dopaminergic neuronal death caused by the neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine

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12 December 2020

Threshold effects and control of oxidative phosphorylation in nonsynaptic rat brain mitochondria.

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12 December 2020

Absence of MPTP-induced neuronal death in mice lacking the dopamine transporter.

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12 December 2020

Studies on the neurotoxicity of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine: inhibition of NAD-linked substrate oxidation by its metabolite, 1-methyl-4-phenylpyridinium

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12 December 2020

Inhibition of mitochondrial alpha-ketoglutarate dehydrogenase by 1-methyl-4-phenylpyridinium ion

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12 December 2020

Protection against the dopaminergic neurotoxicity of 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine by monoamine oxidase inhibitors

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12 December 2020

Evidence that the inhibition sites of the neurotoxic amine 1-methyl-4-phenylpyridinium (MPP+) and of the respiratory chain inhibitor piericidin A are the same

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12 December 2020

Distribution of type B monoamine oxidase immunoreactivity in the cat brain with reference to enzyme histochemistry

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12 December 2020

Parkinsonism-inducing neurotoxin, N-methyl-4-phenyl-1,2,3,6 -tetrahydropyridine: uptake of the metabolite N-methyl-4-phenylpyridine by dopamine neurons explains selective toxicity

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12 December 2020

Reactivation of NADH dehydrogenase (complex I) inhibited by 1-methyl-4-(4'-alkylphenyl)pyridinium analogues: a clue to the nature of the inhibition site

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12 December 2020

Inhibition of NADH-linked oxidation in brain mitochondria by 1-methyl-4-phenyl-pyridine, a metabolite of the neurotoxin, 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine

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12 December 2020

Bax ablation prevents dopaminergic neurodegeneration in the 1-methyl- 4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson's disease

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12 December 2020

Functional coupling of PSST and ND1 subunits in NADH:ubiquinone oxidoreductase established by photoaffinity labeling

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12 December 2020

Intraneuronal generation of a pyridinium metabolite may cause drug-induced parkinsonism

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12 December 2020

Manganese superoxide dismutase overexpression attenuates MPTP toxicity.

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12 December 2020

Inhibition of mitochondrial respiration by analogs of 4-phenylpyridine and 1-methyl-4-phenylpyridinium cation (MPP+), the neurotoxic metabolite of MPTP

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12 December 2020

1-Methyl-4-phenylpyridinium (MPP+) induces NADH-dependent superoxide formation and enhances NADH-dependent lipid peroxidation in bovine heart submitochondrial particles

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12 December 2020

Mice with a partial deficiency of manganese superoxide dismutase show increased vulnerability to the mitochondrial toxins malonate, 3-nitropropionic acid, and MPTP.

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12 December 2020

Piperidine derivatives. Part III. 4-arylpiperidines

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12 December 2020

Structural dependence of the inhibition of mitochondrial respiration and of NADH oxidase by 1-methyl-4-phenylpyridinium (MPP+) analogs and their energized accumulation by mitochondria

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12 December 2020

Parkinson's disease: mechanisms and models

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12 December 2020

Probing the ubiquinone reduction site of mitochondrial complex I using novel cationic inhibitors

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12 December 2020

10.1023/B:JOBB.0000041771.66775.D5

Identifiers

DOI

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Dimensions Publication ID

11 August 2017

1032430633

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