(Q34868039)

5 August 2017

The topoisomerase IIbeta circular clamp arrests transcription and signals a 26S proteasome pathway (English)

1 reference

5 August 2017

Leroy F Liu

7

0 references

author name string

Hai Xiao

1

1 reference

5 August 2017

Yong Mao

2

1 reference

5 August 2017

Shyamal D Desai

3

1 reference

5 August 2017

Nai Zhou

4

1 reference

5 August 2017

Chun-Yuan Ting

5

1 reference

5 August 2017

Jaulang Hwang

6

1 reference

5 August 2017

language of work or name

English

0 references

publication date

10 March 2003

1 reference

Proceedings of the National Academy of Sciences of the United States of America

5 August 2017

1 reference

5 August 2017

100

1 reference

5 August 2017

6

1 reference

5 August 2017

3239-3244

1 reference

Transcript elongation on a nucleoprotein template

5 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=152276

Transcription-coupled and DNA damage-dependent ubiquitination of RNA polymerase II in vitro

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=152276

Ubiquitin/26S proteasome-mediated degradation of topoisomerase I as a resistance mechanism to camptothecin in tumor cells.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=152276

Co-localization of chicken DNA topoisomerase IIalpha, but not beta, with sites of DNA replication and possible involvement of a C-terminal region of alpha through its binding to PCNA.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=152276

The 19S regulatory particle of the proteasome is required for efficient transcription elongation by RNA polymerase II.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=152276

Tumor cell death induced by topoisomerase-targeting drugs.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=152276

The catalytic DNA topoisomerase II inhibitor dexrazoxane (ICRF-187) induces differentiation and apoptosis in human leukemia K562 cells.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=152276

The 26S proteasome: ubiquitin-mediated proteolysis in the tunnel

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=152276

SUMO-1 conjugation to human DNA topoisomerase II isozymes

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=152276

DNA topoisomerase IIbeta and neural development

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=152276

Induction of apoptosis by dexrazoxane (ICRF-187) through caspases in the absence of c-jun expression and c-Jun NH2-terminal kinase 1 (JNK1) activation in VM-26-resistant CEM cells

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=152276

Factors regulating the transcriptional elongation activity of RNA polymerase II

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=152276

Ultraviolet radiation-induced ubiquitination and proteasomal degradation of the large subunit of RNA polymerase II. Implications for transcription-coupled DNA repair

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=152276

Antitumor bisdioxopiperazines inhibit yeast DNA topoisomerase II by trapping the enzyme in the form of a closed protein clamp

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=152276

DNA topoisomerase II is the molecular target of bisdioxopiperazine derivatives ICRF-159 and ICRF-193 in Saccharomyces cerevisiae.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=152276

Analysis of topoisomerase I/DNA complexes in patients administered topotecan.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=152276

Alterations in the topoisomerase II alpha gene, messenger RNA, and subcellular protein distribution as well as reduced expression of the DNA topoisomerase II beta enzyme in a mitoxantrone-resistant HL-60 human leukemia cell line.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=152276

Topoisomerase-II-mediated DNA cleavage within the human ribosomal genes.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=152276

Involvement of DNA topoisomerase I in transcription of human ribosomal RNA genes.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=152276

Biochemical and pharmacological properties of p170 and p180 forms of topoisomerase II.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=152276

Topoisomerase-targeting antitumor drugs

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=152276

Proliferation- and cell cycle-dependent differences in expression of the 170 kilodalton and 180 kilodalton forms of topoisomerase II in NIH-3T3 cells

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=152276

Isolation of cDNA clones encoding the beta isozyme of human DNA topoisomerase II and localisation of the gene to chromosome 3p24

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=152276

Topoisomerase II alpha and topoisomerase II beta genes: characterization and mapping to human chromosomes 17 and 3, respectively

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=152276

26 S proteasome-mediated degradation of topoisomerase II cleavable complexes.

8 July 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0736401100

Involvement of DNA topoisomerase IIbeta in neuronal differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0736401100

Murine transgenic cells lacking DNA topoisomerase IIbeta are resistant to acridines and mitoxantrone: analysis of cytotoxicity and cleavable complex formation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0736401100

RNA synthesis block by 5, 6-dichloro-1-beta-D-ribofuranosylbenzimidazole (DRB) triggers p53-dependent apoptosis in human colon carcinoma cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0736401100

Topoisomerase II poisoning by ICRF-193.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0736401100

Atp-bound topoisomerase ii as a target for antitumor drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0736401100

ATR enforces the topoisomerase II-dependent G2 checkpoint through inhibition of Plk1 kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0736401100

Cell death induced by topoisomerase-targeted drugs: more questions than answers

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0736401100

Ubiquitin-dependent destruction of topoisomerase I is stimulated by the antitumor drug camptothecin

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0736401100

Catalytic inhibitors of DNA topoisomerase II

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0736401100

Inhibition of RNA polymerase II as a trigger for the p53 response

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0736401100

Steady-state and rapid kinetic analysis of topoisomerase II trapped as the closed-clamp intermediate by ICRF-193

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0736401100

A novel mechanism of cell killing by anti-topoisomerase II bisdioxopiperazines

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0736401100

Use of yeast in the study of anticancer drugs targeting DNA topoisomerases: expression of a functional recombinant human DNA topoisomerase II alpha in yeast

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/12629207

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Differential immunohistochemical staining for DNA topoisomerase II alpha and beta in human tissues and for DNA topoisomerase II beta in non-Hodgkin's lymphomas

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/12629207

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.0736401100

1 reference

5 August 2017

0 references

1 reference

5 August 2017

1 reference