(Q34869281)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21388963%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

title

Islet-1 regulates Arx transcription during pancreatic islet alpha-cell development (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21388963%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21388963%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

author name string

Jingxuan Liu

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21388963%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

Aiping Du

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21388963%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

Benjamin Ediger

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21388963%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

Erik Walp

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21388963%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

Johanna Murray

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21388963%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

Roland Stein

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21388963%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

Catherine Lee May

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21388963%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

language of work or name

English

0 references

publication date

9 March 2011

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21388963%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

number of pages

9

1 reference

Journal of Biological Chemistry

inferred from page(s)

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21388963%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

volume

286

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21388963%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

issue

17

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21388963%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

page(s)

15352-15360

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21388963%20AND%20SRC:MED&resulttype=core&format=json

Glucagon deficiency reduces hepatic glucose production and improves glucose tolerance in adult mice

25 January 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083195

The ectopic expression of Pax4 in the mouse pancreas converts progenitor cells into alpha and subsequently beta cells

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083195

Extracting transcription factor targets from ChIP-Seq data

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083195

Islet-1 is required for the maturation, proliferation, and survival of the endocrine pancreas.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083195

Arx is a direct target of Dlx2 and thereby contributes to the tangential migration of GABAergic interneurons

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083195

Making insulin-deficient type 1 diabetic rodents thrive without insulin

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083195

On the origin of the beta cell

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083195

Deletion of ultraconserved elements yields viable mice

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083195

Embryonic endocrine pancreas and mature beta cells acquire alpha and PP cell phenotypes upon Arx misexpression.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083195

Expansion of adult beta-cell mass in response to increased metabolic demand is dependent on HNF-4alpha

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083195

Alpha-cells of the endocrine pancreas: 35 years of research but the enigma remains

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083195

The simultaneous loss of Arx and Pax4 genes promotes a somatostatin-producing cell fate specification at the expense of the alpha- and beta-cell lineages in the mouse endocrine pancreas

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083195

Foxa2 is required for the differentiation of pancreatic alpha-cells

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083195

Cell lines derived from pancreatic islets

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083195

Isl1 identifies a cardiac progenitor population that proliferates prior to differentiation and contributes a majority of cells to the heart

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083195

LIM-domain-binding protein 1: a multifunctional cofactor that interacts with diverse proteins.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083195

Opposing actions of Arx and Pax4 in endocrine pancreas development

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083195

Expression of neurogenin3 reveals an islet cell precursor population in the pancreas

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083195

beta-cell-specific inactivation of the mouse Ipf1/Pdx1 gene results in loss of the beta-cell phenotype and maturity onset diabetes

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083195

Hepatocyte nuclear factor 3beta is involved in pancreatic beta-cell-specific transcription of the pdx-1 gene

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083195

A family of LIM domain-associated cofactors confer transcriptional synergism between LIM and Otx homeodomain proteins

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083195

Independent requirement for ISL1 in formation of pancreatic mesenchyme and islet cells

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083195

Molecular and cellular aspects of the glucagon receptor: role in diabetes and metabolism.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083195

Interactions of the LIM-domain-binding factor Ldb1 with LIM homeodomain proteins

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083195

The morphogenesis of the pancreatic mesenchyme is uncoupled from that of the pancreatic epithelium in IPF1/PDX1-deficient mice

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083195

Requirement for LIM homeobox gene Isl1 in motor neuron generation reveals a motor neuron-dependent step in interneuron differentiation

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083195

The LIM domain homeobox gene isl-1 is a positive regulator of islet cell-specific proglucagon gene transcription

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083195

Glucagon and the Insulin:Glucagon Ratio in Diabetes and Other Catabolic Illnesses

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083195

Rapid detection of octamer binding proteins with 'mini-extracts', prepared from a small number of cells

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083195

The homeodomain LIM protein Isl-1 is expressed in subsets of neurons and endocrine cells in the adult rat.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083195

Insulin gene enhancer binding protein Isl-1 is a member of a novel class of proteins containing both a homeo- and a Cys-His domain

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083195

Autoregulation of endogenous glucose production during hyperglucagonemia

8 July 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.231670

MafB: an activator of the glucagon gene expressed in developing islet alpha- and beta-cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.231670

Partial loss of pancreas endocrine and exocrine cells of human ARX-null mutation: consideration of pancreas differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.231670

The vertebrate ortholog of Aristaless is regulated by Dlx genes in the developing forebrain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.231670

Homeobox gene Nkx6.1 lies downstream of Nkx2.2 in the major pathway of beta-cell formation in the pancreas.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083195

Persistent expression of HNF6 in islet endocrine cells causes disrupted islet architecture and loss of beta cell function.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083195

The Pax4 gene is essential for differentiation of insulin-producing β cells in the mammalian pancreas

26 October 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.231670

An ultrastructural analysis of the developing embryonic pancreas

21 January 2018

1 reference

12 December 2020

Glucagon: Role in the Hyperglycemia of Diabetes Mellitus

1 reference

12 December 2020

Prevention of human diabetic ketoacidosis by somatostatin. Evidence for an essential role of glucagon

1 reference

12 December 2020

Hyperglucagonemia and its suppression. Importance in the metabolic control of diabetes

1 reference

12 December 2020

Possible mechanism by which somatostatin-induced glucagon suppression improves glucose tolerance during insulinopaenia in man

1 reference

12 December 2020

Identifiers

DOI

10.1074/JBC.M111.231670

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21388963%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21388963%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

PubMed publication ID

21388963

1 reference