(Q34889576)

5 August 2017

title

The effects of the selective 5-HT(2C) receptor antagonist SB 242084 on learned helplessness in male Fischer 344 rats (English)

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5 August 2017

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Monika Fleshner

3

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author name string

Paul V Strong

series ordinal

1

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5 August 2017

Benjamin N Greenwood

series ordinal

2

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5 August 2017

publication date

27 November 2008

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5 August 2017

number of pages

11

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inferred from page(s)

published in

Psychopharmacology

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5 August 2017

volume

203

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5 August 2017

issue

4

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5 August 2017

page(s)

665-675

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Distribution of the 5-hydroxytryptamine2C receptor protein in adult rat brain and spinal cord determined using a receptor-directed antibody: effect of 5,7-dihydroxytryptamine

5 August 2017

cites work

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The dorsal raphe nucleus is a site of action mediating the behavioral effects of the benzodiazepine receptor inverse agonist DMCM.

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Librium prevents the analgesia and shuttlebox escape deficit typically observed following inescapable shock.

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5-Hydroxytryptamine2C receptor contribution to m-chlorophenylpiperazine and N-methyl-beta-carboline-3-carboxamide-induced anxiety-like behavior and limbic brain activation

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8-OH-DPAT microinjected in the region of the dorsal raphe nucleus blocks and reverses the enhancement of fear conditioning and interference with escape produced by exposure to inescapable shock.

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Serotonin, the periaqueductal gray and panic

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12 December 2020

5-HT2 receptor mechanisms of the dorsal periaqueductal gray in the conditioned and unconditioned fear in rats.

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12 December 2020

The effects of chronic treadmill and wheel running on behavior in rats

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12 December 2020

6-Chloro-5-methyl-1-[[2-[(2-methyl-3-pyridyl)oxy]-5-pyridyl]carbamoyl]- indoline (SB-242084): the first selective and brain penetrant 5-HT2C receptor antagonist

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12 December 2020

Exposure to inescapable but not escapable shock increases extracellular levels of 5-HT in the dorsal raphe nucleus of the rat.

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12 December 2020

Serotonin 2C receptors within the basolateral amygdala induce acute fear-like responses in an open-field environment

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12 December 2020

Behavioral control, the medial prefrontal cortex, and resilience

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12 December 2020

Previous experience with behavioral control over stress blocks the behavioral and dorsal raphe nucleus activating effects of later uncontrollable stress: role of the ventral medial prefrontal cortex.

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12 December 2020

Serotonin 5-HT2C receptors as a target for the treatment of depressive and anxious states: focus on novel therapeutic strategies

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12 December 2020

Anxiolytic activity of a novel potent serotonin 5-HT2C receptor antagonist FR260010: a comparison with diazepam and buspirone

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12 December 2020

Dual role of 5-HT in defense and anxiety

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12 December 2020

5-HT1c receptor is a prominent serotonin receptor subtype in the central nervous system

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12 December 2020

Anxiogenic-like effects of mCPP microinfusions into the amygdala (but not dorsal or ventral hippocampus) in mice exposed to elevated plus-maze.

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Genetic variation in cortico-amygdala serotonin function and risk for stress-related disease

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12 December 2020

Exercise, learned helplessness, and the stress-resistant brain

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12 December 2020

Stressor controllability and learned helplessness: the roles of the dorsal raphe nucleus, serotonin, and corticotropin-releasing factor

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12 December 2020

The neurobiology and control of anxious states

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12 December 2020

Effects of acute and subchronic treatments with fluoxetine and desipramine on the memory of fear in moderate and high-intensity contextual conditioning

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12 December 2020

Activation of serotonin-immunoreactive cells in the dorsal raphe nucleus in rats exposed to an uncontrollable stressor

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12 December 2020

Exposure to the stressor environment prevents the temporal dissipation of behavioral depression/learned helplessness.

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12 December 2020

Evidence that mCPP-induced anxiety in the plus-maze is mediated by postsynaptic 5-HT2C receptors but not by sympathomimetic effects.

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12 December 2020

Activation of the serotonin 5-HT2C receptor is involved in the enhanced anxiety in rats after single-prolonged stress

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12 December 2020

The role of the amygdala and dorsal raphe nucleus in mediating the behavioral consequences of inescapable shock

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12 December 2020

5-HT2 receptor activation in the midbrain periaqueductal grey (PAG) reduces anxiety-like behaviour in mice

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12 December 2020

Chlordiazepoxide microinjected into the region of the dorsal raphe nucleus eliminates the interference with escape responding produced by inescapable shock whether administered before inescapable shock or escape testing

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12 December 2020

Anxiolytic properties of the selective, non-peptidergic CRF(1) antagonists, CP154,526 and DMP695: a comparison to other classes of anxiolytic agent

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12 December 2020

Influence of the 5-HT2C receptor antagonist, SB-242084, in tests of anxiety

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12 December 2020

Immunohistochemical localisation of the 5-HT2C receptor protein in the rat CNS.

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12 December 2020

Anxiogenic-like effects of mCPP and TFMPP in animal models are opposed by 5-HT1C receptor antagonists

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12 December 2020

Serotonin 5- HT (2C) receptor knockout mice: autoradiographic analysis of multiple serotonin receptors

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12 December 2020

Learned helplessness is independent of levels of brain-derived neurotrophic factor in the hippocampus

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12 December 2020

Antidepressant-like effects of the novel, selective, 5-HT2C receptor agonist WAY-163909 in rodents

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12 December 2020

Effect of number of tailshocks on learned helplessness and activation of serotonergic and noradrenergic neurons in the rat.

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12 December 2020

CP-809,101, a selective 5-HT2C agonist, shows activity in animal models of antipsychotic activity

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12 December 2020

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12 December 2020

Freewheel running prevents learned helplessness/behavioral depression: role of dorsal raphe serotonergic neurons.

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12 December 2020

Role of fear in mediating shuttle escape learning deficit produced by inescapable shock

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12 December 2020

Acute selective serotonin reuptake inhibitors increase conditioned fear expression: blockade with a 5-HT(2C) receptor antagonist

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12 December 2020

Brain region-specific alterations of 5-HT2A and 5-HT2C receptors in serotonin transporter knockout mice

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12 December 2020

5-Hydroxytryptamine-interacting drugs in animal models of anxiety disorders: More than 30 years of research

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12 December 2020

5-HT2C receptor mediation of unconditioned escape behaviour in the unstable elevated exposed plus maze

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12 December 2020

Effects of centrally administered anxiolytic compounds in animal models of anxiety

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12 December 2020

Use of serotonergic agents in the clinical assessment of central serotonin function

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12 December 2020

Serotonergic systems associated with arousal and vigilance behaviors following administration of anxiogenic drugs.

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12 December 2020

Comparative localization of serotonin1A, 1C, and2 receptor subtype mRNAs in rat brain

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12 December 2020

Distribution of the serotonin 5-HT2 receptor family mRNAs: comparison between 5-HT2A and 5-HT2C receptors

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12 December 2020

Role of 5-HT in stress, anxiety, and depression.

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12 December 2020

SB 242084, a selective and brain penetrant 5-HT2C receptor antagonist

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12 December 2020

Role of the amygdala and periaqueductal gray in anxiety and panic

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12 December 2020

Localization of the 5-hydroxytryptamine2C receptor protein in human and rat brain using specific antisera.

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12 December 2020

Anxiety-like effects induced by acute fluoxetine, sertraline or m-CPP treatment are reversed by pretreatment with the 5-HT2C receptor antagonist SB-242084 but not the 5-HT1A receptor antagonist WAY-100635.

1 reference

12 December 2020

Neuroanatomical targets of anxiogenic drugs in the hindbrain as revealed by Fos immunocytochemistry.

1 reference

12 December 2020

Anxiety-like behaviors produced by acute fluoxetine administration in male Fischer 344 rats are prevented by prior exercise

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12 December 2020

10.1007/S00213-008-1413-3

Identifiers

DOI

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Dimensions Publication ID

5 August 2017

1038499177

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