(Q34898429)

5 August 2017

title

Gene-environment interactions in Parkinson's disease: the importance of animal modeling (English)

1 reference

5 August 2017

1 reference

M P Horowitz

1

1 reference

5 August 2017

J T Greenamyre

series ordinal

2

1 reference

5 August 2017

language of work or name

English

0 references

publication date

1 September 2010

1 reference

Clinical Pharmacology & Therapeutics

5 August 2017

published in

1 reference

5 August 2017

volume

88

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5 August 2017

issue

4

1 reference

5 August 2017

page(s)

467-474

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Advances in environmental epidemiology

5 August 2017

cites work

1 reference

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8 July 2018

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Lessons from the rotenone model of Parkinson's disease

8 July 2018

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Parkin protects against LRRK2 G2019S mutant-induced dopaminergic neurodegeneration in Drosophila.

8 July 2018

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Leucine-Rich Repeat Kinase 2 interacts with Parkin, DJ-1 and PINK-1 in a Drosophila melanogaster model of Parkinson's disease

8 July 2018

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LRRK2 modulates vulnerability to mitochondrial dysfunction in Caenorhabditis elegans

8 July 2018

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Mutant LRRK2(R1441G) BAC transgenic mice recapitulate cardinal features of Parkinson's disease

8 July 2018

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8 July 2018

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Parkinson's disease: from monogenic forms to genetic susceptibility factors

8 July 2018

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Parkinson's disease and residential exposure to maneb and paraquat from agricultural applications in the central valley of California

8 July 2018

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Parkin is recruited selectively to impaired mitochondria and promotes their autophagy

8 July 2018

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Nicotine and Parkinson's disease: implications for therapy

8 July 2018

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Genomic investigation of alpha-synuclein multiplication and parkinsonism

8 July 2018

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Phenotype, genotype, and worldwide genetic penetrance of LRRK2-associated Parkinson's disease: a case-control study

8 July 2018

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Elevated alpha-synuclein mRNA levels in individual UV-laser-microdissected dopaminergic substantia nigra neurons in idiopathic Parkinson's disease

8 July 2018

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Cytoplasmic Pink1 activity protects neurons from dopaminergic neurotoxin MPTP.

8 July 2018

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Behavioral and histopathological consequences of paraquat intoxication in mice: effects of alpha-synuclein over-expression

8 July 2018

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Plasma urate and risk of Parkinson's disease

8 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3085510

Impaired dopamine release and synaptic plasticity in the striatum of PINK1-deficient mice

8 July 2018

1 reference

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Pesticide exposure exacerbates alpha-synucleinopathy in an A53T transgenic mouse model

8 July 2018

1 reference

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Drosophila pink1 is required for mitochondrial function and interacts genetically with parkin

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3085510

Mitochondrial dysfunction in Drosophila PINK1 mutants is complemented by parkin

8 July 2018

1 reference

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Parkinson's disease-associated mutations in leucine-rich repeat kinase 2 augment kinase activity

8 July 2018

1 reference

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Pathogenic effects of alpha-synuclein aggregation.

8 July 2018

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Hypersensitivity of DJ-1-deficient mice to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyrindine (MPTP) and oxidative stress.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3085510

Mutations in LRRK2 cause autosomal-dominant parkinsonism with pleomorphic pathology

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3085510

Cloning of the gene containing mutations that cause PARK8-linked Parkinson's disease

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3085510

The Parkinson's disease protein DJ-1 is neuroprotective due to cysteine-sulfinic acid-driven mitochondrial localization

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3085510

Hereditary early-onset Parkinson's disease caused by mutations in PINK1

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3085510

Mitochondrial dysfunction and oxidative damage in parkin-deficient mice

8 July 2018

1 reference

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alpha-Synuclein locus triplication causes Parkinson's disease

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3085510

Mutations in the DJ-1 gene associated with autosomal recessive early-onset parkinsonism

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3085510

Effect of allelic variation at the NACP-Rep1 repeat upstream of the alpha-synuclein gene (SNCA) on transcription in a cell culture luciferase reporter system

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3085510

Prospective study of caffeine consumption and risk of Parkinson's disease in men and women.

8 July 2018

1 reference

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Chronic systemic pesticide exposure reproduces features of Parkinson's disease

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3085510

Parkinson's disease mortality and pesticide exposure in California 1984-1994.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3085510

A Drosophila model of Parkinson's disease

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3085510

Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3085510

Alpha-synuclein in Lewy bodies

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3085510

Mutation in the alpha-synuclein gene identified in families with Parkinson's disease

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3085510

Chronic Parkinsonism in humans due to a product of meperidine-analog synthesis

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3085510

Alpha-synuclein in blood and brain from familial Parkinson disease with SNCA locus triplication

8 July 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2010.138

Pesticide exposure and self-reported Parkinson's disease in the agricultural health study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2010.138

The herbicide paraquat causes up-regulation and aggregation of alpha-synuclein in mice: paraquat and alpha-synuclein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2010.138

Trichloroethylene: Parkinsonism and complex 1 mitochondrial neurotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2010.138

Sensitivity to MPTP is not increased in Parkinson's disease-associated mutant alpha-synuclein transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2010.138

Increased sensitivity to MPTP in human alpha-synuclein A30P transgenic mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2010.138

Prosurvival effect of human wild-type alpha-synuclein on MPTP-induced toxicity to central but not peripheral catecholaminergic neurons isolated from transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2010.138

Enhanced substantia nigra mitochondrial pathology in human alpha-synuclein transgenic mice after treatment with MPTP.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2010.138

Susceptibility to rotenone is increased in neurons from parkin null mice and is reduced by minocycline.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2010.138

Drosophila overexpressing parkin R275W mutant exhibits dopaminergic neuron degeneration and mitochondrial abnormalities.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2010.138

Drosophila DJ-1 mutants are selectively sensitive to environmental toxins associated with Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2010.138

Increased vulnerability of nigrostriatal terminals in DJ-1-deficient mice is mediated by the dopamine transporter

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2010.138

α-Synuclein Overexpression Protects against Paraquat-Induced Neurodegeneration

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3085510

A meta-analysis of Parkinson's disease and exposure to pesticides

26 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20811350

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/CLPT.2010.138

1 reference

5 August 2017

1 reference

5 August 2017

1 reference