(Q34905762)

English

Lysine-specific demethylase 1 (LSD1/KDM1A) contributes to colorectal tumorigenesis via activation of the Wnt/β-catenin pathway by down-regulating Dickkopf-1 (DKK1) [corrected].

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scholarly article

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Europe PubMed Central

5 August 2017

Lysine-specific demethylase 1 (LSD1/KDM1A) contributes to colorectal tumorigenesis via activation of the Wnt/β-catenin pathway by down-regulating Dickkopf-1 (DKK1) [corrected]. (English)

1 reference

Europe PubMed Central

5 August 2017

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author name string

Zebin Huang

1

1 reference

Europe PubMed Central

5 August 2017

Shangze Li

2

1 reference

Europe PubMed Central

5 August 2017

Wei Song

3

1 reference

Europe PubMed Central

5 August 2017

Xin Li

4

1 reference

Europe PubMed Central

5 August 2017

Qinshan Li

5

1 reference

Europe PubMed Central

5 August 2017

Zeyan Zhang

6

1 reference

Europe PubMed Central

5 August 2017

Yongqing Han

7

1 reference

Europe PubMed Central

5 August 2017

Xiaodong Zhang

8

1 reference

Europe PubMed Central

5 August 2017

Shiying Miao

9

1 reference

Europe PubMed Central

5 August 2017

Runlei Du

10

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5 August 2017

Linfang Wang

11

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5 August 2017

language of work or name

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publication date

26 July 2013

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Europe PubMed Central

5 August 2017

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Europe PubMed Central

5 August 2017

8

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Europe PubMed Central

5 August 2017

7

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Europe PubMed Central

5 August 2017

e70077

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Europe PubMed Central

5 August 2017

copyright license

Creative Commons Attribution 4.0 International

26 July 2013

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April 2022 Public Data File from Crossref

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Loss of LSD1 (lysine-specific demethylase 1) suppresses growth and alters gene expression of human colon cancer cells in a p53- and DNMT1(DNA methyltransferase 1)-independent manner.

1 reference

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8 July 2018

Over-expression of LSD1 promotes proliferation, migration and invasion in non-small cell lung cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3724785

8 July 2018

Inhibition of the LSD1 (KDM1A) demethylase reactivates the all-trans-retinoic acid differentiation pathway in acute myeloid leukemia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3724785

8 July 2018

Transcriptional silencing of the Wnt-antagonist DKK1 by promoter methylation is associated with enhanced Wnt signaling in advanced multiple myeloma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3724785

8 July 2018

Dynamic interaction between TAL1 oncoprotein and LSD1 regulates TAL1 function in hematopoiesis and leukemogenesis

1 reference

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Cryptotanshinone down-regulates androgen receptor signaling by modulating lysine-specific demethylase 1 function.

1 reference

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8 July 2018

Cross-talk between phospho-STAT3 and PLCγ1 plays a critical role in colorectal tumorigenesis

1 reference

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8 July 2018

Inhibition of hyaluronan synthase-3 decreases subcutaneous colon cancer growth by increasing apoptosis

1 reference

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8 July 2018

RCOR2 is a subunit of the LSD1 complex that regulates ESC property and substitutes for SOX2 in reprogramming somatic cells to pluripotency

1 reference

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8 July 2018

Role of androgen receptor and associated lysine-demethylase coregulators, LSD1 and JMJD2A, in localized and advanced human bladder cancer.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3724785

8 July 2018

Lysine-specific demethylase 1 regulates the embryonic transcriptome and CoREST stability

1 reference

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8 July 2018

Conversion of mouse epiblast stem cells to an earlier pluripotency state by small molecules.

1 reference

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8 July 2018

Histone demethylase LSD1 regulates adipogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3724785

8 July 2018

Lysine methylation regulates E2F1-induced cell death

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3724785

8 July 2018

Downregulation of Dickkopf-1 is responsible for high proliferation of breast cancer cells via losing control of Wnt/beta-catenin signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3724785

8 July 2018

Lysine-specific demethylase 1 (LSD1) is highly expressed in ER-negative breast cancers and a biomarker predicting aggressive biology

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3724785

8 July 2018

Molecular origins of cancer: Molecular basis of colorectal cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3724785

8 July 2018

LSD1 is a subunit of the NuRD complex and targets the metastasis programs in breast cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3724785

8 July 2018

Lysine-specific demethylase 1 is strongly expressed in poorly differentiated neuroblastoma: implications for therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3724785

8 July 2018

The lysine demethylase LSD1 (KDM1) is required for maintenance of global DNA methylation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3724785

8 July 2018

Wnt signalling and its impact on development and cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3724785

8 July 2018

Frequent epigenetic inactivation of Wnt antagonist genes in breast cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3724785

8 July 2018

Epitope tagging of endogenous proteins for genome-wide ChIP-chip studies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3724785

8 July 2018

Dickkopf-1 mediated tumor suppression in human breast carcinoma cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3724785

8 July 2018

Genetic knockouts and knockins in human somatic cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3724785

8 July 2018

Proliferation and migration mediated by Dkk-1/Wnt/beta-catenin cascade in a model of hepatocellular carcinoma cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3724785

8 July 2018

p53 is regulated by the lysine demethylase LSD1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3724785

8 July 2018

Frequent epigenetic inactivation of DICKKOPF family genes in human gastrointestinal tumors.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3724785

8 July 2018

A two-way street: LSD1 regulates chromatin boundary formation in S. pombe and Drosophila.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3724785

8 July 2018

Inhibition of lysine-specific demethylase 1 by polyamine analogues results in reexpression of aberrantly silenced genes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3724785

8 July 2018

The lysine-specific demethylase 1 is required for cell proliferation in both p53-dependent and -independent manners

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3724785

8 July 2018

Wnt signaling pathway in mammary gland development and carcinogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3724785

8 July 2018

Wnt/beta-catenin signaling in development and disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3724785

8 July 2018

Wnt signaling: is the party in the nucleus?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3724785

8 July 2018

Epigenetic inactivation of the Wnt antagonist DICKKOPF-1 (DKK-1) gene in human colorectal cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3724785

8 July 2018

The diverse functions of histone lysine methylation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3724785

8 July 2018

Regulation of LSD1 histone demethylase activity by its associated factors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3724785

8 July 2018

LSD1 demethylates repressive histone marks to promote androgen-receptor-dependent transcription

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3724785

8 July 2018

An essential role for CoREST in nucleosomal histone 3 lysine 4 demethylation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3724785

8 July 2018

Wnt signalling and the mechanistic basis of tumour development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3724785

8 July 2018

Histone demethylation mediated by the nuclear amine oxidase homolog LSD1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3724785

8 July 2018

Liver-targeted disruption of Apc in mice activates beta-catenin signaling and leads to hepatocellular carcinomas

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3724785

8 July 2018

Facile methods for generating human somatic cell gene knockouts using recombinant adeno-associated viruses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3724785

8 July 2018

Caught up in a Wnt storm: Wnt signaling in cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3724785

8 July 2018

Kremen proteins are Dickkopf receptors that regulate Wnt/beta-catenin signalling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3724785

8 July 2018

TCF transcription factors, mediators of Wnt-signaling in development and cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3724785

8 July 2018

Transcription regulation by histone methylation: interplay between different covalent modifications of the core histone tails

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3724785

8 July 2018

LDL-receptor-related protein 6 is a receptor for Dickkopf proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3724785

8 July 2018

Identification of c-MYC as a target of the APC pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3724785

8 July 2018

A variant of Smurf2 protects mice against colitis-associated colon cancer by inducing transforming growth factor β signaling.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3724785

26 October 2018

Demethylation of RB regulator MYPT1 by histone demethylase LSD1 promotes cell cycle progression in cancer cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3724785

26 October 2018

Role of different inflammatory and tumor biomarkers in the development of ulcerative colitis-associated carcinogenesis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3724785

26 October 2018

LSD1 is required for chromosome segregation during mitosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3724785

26 October 2018

Dynamic regulation of histone H3 methylation at lysine 4 in mammalian spermatogenesis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3724785

26 October 2018

Targeted transgene insertion into human chromosomes by adeno-associated virus vectors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3724785

26 October 2018

The Wnt antagonist DICKKOPF-1 gene is a downstream target of beta-catenin/TCF and is downregulated in human colon cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/23922913

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Wnt antagonist DKK1 acts as a tumor suppressor gene that induces apoptosis and inhibits proliferation in human renal cell carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/23922913

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dickkopf-1 inhibits epithelial-mesenchymal transition of colon cancer cells and contributes to colon cancer suppression.

1 reference

https://pubmed.ncbi.nlm.nih.gov/23922913

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1371/JOURNAL.PONE.0070077

1 reference

Europe PubMed Central

5 August 2017

2013PLoSO...870077H

0 references

1 reference

Europe PubMed Central

5 August 2017

1 reference

Europe PubMed Central

5 August 2017

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