(Q34912705)

5 August 2017

A microfluidic device to study cancer metastasis under chronic and intermittent hypoxia (English)

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5 August 2017

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Kyle B Cutler

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Xiao Jiang

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Xiao Jiang

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Christine S. Grant

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Christine S Grant

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author name string

Miguel A Acosta

1

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5 August 2017

Pin-Kang Huang

3

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5 August 2017

Glenn M Walker

6

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5 August 2017

Michael P Gamcsik

7

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5 August 2017

1 September 2014

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5 August 2017

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5 August 2017

8

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5 August 2017

5

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5 August 2017

054117

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describes a project that uses

5 August 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4290574/fullTextXML

inferred from PubMed Central ID database lookup

cites work

Three-dimensional paper-based model for cardiac ischemia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4290574

Rapid uptake of glucose and lactate, and not hypoxia, induces apoptosis in three-dimensional tumor tissue culture

8 July 2018

1 reference

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Probing hypoxia-induced staurosporine resistance in prostate cancer cells with a microfluidic culture system

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4290574

Intermittent hypoxia-induced changes in tumor-associated macrophages and tumor malignancy in a mouse model of sleep apnea.

8 July 2018

1 reference

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A microfluidic 3D in vitro model for specificity of breast cancer metastasis to bone

8 July 2018

1 reference

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Hypoxia and regulation of cancer cell stemness

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4290574

Modeling of cancer metastasis and drug resistance via biomimetic nano-cilia and microfluidics

8 July 2018

1 reference

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Hedgehog signaling regulates hypoxia induced epithelial to mesenchymal transition and invasion in pancreatic cancer cells via a ligand-independent manner

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4290574

Predicting efficacy of cancer cell killing under hypoxic conditions with single cell DNA damage assay

8 July 2018

1 reference

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Three dimensional multicellular co-cultures and anti-cancer drug assays in rapid prototyped multilevel microfluidic devices

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4290574

A novel microfluidic platform for high-resolution imaging of a three-dimensional cell culture under a controlled hypoxic environment

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4290574

Studies of bacterial aerotaxis in a microfluidic device

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4290574

Microfluidic device for studying cell migration in single or co-existing chemical gradients and electric fields

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4290574

Islet preconditioning via multimodal microfluidic modulation of intermittent hypoxia

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4290574

Ischemia/reperfusion injury of primary porcine cardiomyocytes in a low-shear microfluidic culture and analysis device

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4290574

Identification of a stem-like cell population by exposing metastatic breast cancer cell lines to repetitive cycles of hypoxia and reoxygenation

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4290574

Tumour necrosis is a postoperative prognostic marker for pancreatic cancer patients with a high interobserver reproducibility in histological evaluation

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4290574

Precise control over the oxygen conditions within the Boyden chamber using a microfabricated insert

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4290574

Oxygen gradients for open well cellular cultures via microfluidic substrates

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4290574

HIF-1 alpha signaling is augmented during intermittent hypoxia by induction of the Nrf2 pathway in NOX1-expressing adenocarcinoma A549 cells

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4290574

Hypoxia-reoxygenation increase invasiveness of PANC-1 cells through Rac1/MMP-2.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4290574

Effects of acute versus chronic hypoxia on DNA damage responses and genomic instability

8 July 2018

1 reference

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Generation of oxygen gradients with arbitrary shapes in a microfluidic device

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4290574

Relationships between cycling hypoxia, HIF-1, angiogenesis and oxidative stress

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4290574

Engineering microscale cellular niches for three-dimensional multicellular co-cultures

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4290574

Microfluidic endothelium for studying the intravascular adhesion of metastatic breast cancer cells

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4290574

Increased expression of metastasis-related genes in hypoxic cells sorted from cervical and lymph nodal xenograft tumors

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4290574

Fluorescent microparticles for sensing cell microenvironment oxygen levels within 3D scaffolds

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4290574

Cell migration into scaffolds under co-culture conditions in a microfluidic platform.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4290574

Targeting lactate-fueled respiration selectively kills hypoxic tumor cells in mice

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4290574

Redox mechanisms switch on hypoxia-dependent epithelial-mesenchymal transition in cancer cells

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4290574

Noninvasive oxygen measurements and mass transfer considerations in tissue culture flasks

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4290574

Multi-step microfluidic device for studying cancer metastasis

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4290574

Matrigel coated polydimethylsiloxane based microfluidic devices for studying metastatic and non-metastatic cancer cell invasion and migration

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4290574

Quantitative measurement and control of oxygen levels in microfluidic poly(dimethylsiloxane) bioreactors during cell culture

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4290574

A microsystem for sensing and patterning oxidative microgradients during cell culture

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4290574

Cell migration and polarity on microfabricated gradients of extracellular matrix proteins

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4290574

Acute hypoxia enhances spontaneous lymph node metastasis in an orthotopic murine model of human cervical carcinoma

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4290574

Modeling O2 transport within engineered hepatic devices

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4290574

Method for measuring oxygen diffusion coefficients of polymer films by luminescence quenching

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4290574

Reactive nitrogen and oxygen radicals formed during hepatic ischemia-reperfusion kill weakly metastatic colorectal cancer cells

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4290574

Tumor-dependent kinetics of partial pressure of oxygen fluctuations during air and oxygen breathing

8 July 2018

1 reference

Construction of oxygen and chemical concentration gradients in a single microfluidic device for studying tumor cell-drug interactions in a dynamic hypoxia microenvironment.

21 January 2018

1 reference

Simple room temperature bonding of thermoplastics and poly(dimethylsiloxane).

21 January 2018

1 reference

Development of an integrated microfluidic platform for dynamic oxygen sensing and delivery in a flowing medium.

21 January 2018

1 reference

Tumor hypoxia and malignant progression.

21 January 2018

1 reference

21 January 2018

1 reference

Integrated optical sensing of dissolved oxygen in microtiter plates: A novel tool for microbial cultivation

21 January 2018

1 reference

The chemoinvasion assay: a method to assess tumor and endothelial cell invasion and its modulation

21 January 2018

1 reference

Design and development of microbioreactors for long-term cell culture in controlled oxygen microenvironments

21 January 2018

1 reference

12 December 2020

Reversible alteration of calcium dynamics in cardiomyocytes during acute hypoxia transient in a microfluidic platform

1 reference

12 December 2020

Acute (cyclic) hypoxia enhances spontaneous metastasis of KHT murine tumors

1 reference

12 December 2020

Attenuation of reactive oxygen species by antioxidants suppresses hypoxia-induced epithelial-mesenchymal transition and metastasis of pancreatic cancer cells

1 reference

12 December 2020

Neutrophil chemotaxis in linear and complex gradients of interleukin-8 formed in a microfabricated device

1 reference

12 December 2020

Fourier analysis of fluctuations of oxygen tension and blood flow in R3230Ac tumors and muscle in rats

1 reference

12 December 2020

Phase fluorometric sterilizable optical oxygen sensor

1 reference

12 December 2020

Tailoring of sol-gel films for optical sensing of oxygen in gas and aqueous phase

1 reference

12 December 2020

Identifiers

DOI

10.1063/1.4898788

1 reference

5 August 2017

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5 August 2017

1 reference