(Q34917544)

5 August 2017

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title

Making a commitment: cell lineage allocation and axis patterning in the early mouse embryo (English)

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5 August 2017

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Sebastian J Arnold

1

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5 August 2017

Elizabeth J Robertson

series ordinal

2

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5 August 2017

publication date

8 January 2009

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Nature Reviews Molecular Cell Biology

5 August 2017

published in

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5 August 2017

volume

10

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5 August 2017

issue

2

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5 August 2017

page(s)

91-103

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Differentiation of embryonic stem cells to clinically relevant populations: lessons from embryonic development

5 August 2017

cites work

1 reference

Inner cell allocation in the mouse morula: the role of oriented division during fourth cleavage

31 March 2020

1 reference

Interaction between Oct3/4 and Cdx2 determines trophectoderm differentiation

31 March 2020

1 reference

Stochastic patterning in the mouse pre-implantation embryo

31 March 2020

1 reference

Cdx2 acts downstream of cell polarization to cell-autonomously promote trophectoderm fate in the early mouse embryo

31 March 2020

1 reference

Transcription factor TEAD4 specifies the trophectoderm lineage at the beginning of mammalian development

31 March 2020

1 reference

Early lineage segregation between epiblast and primitive endoderm in mouse blastocysts through the Grb2-MAPK pathway

31 March 2020

1 reference

Distinct sequential cell behaviours direct primitive endoderm formation in the mouse blastocyst.

31 March 2020

1 reference

Functional expression cloning of Nanog, a pluripotency sustaining factor in embryonic stem cells

31 March 2020

1 reference

The homeoprotein Nanog is required for maintenance of pluripotency in mouse epiblast and ES cells

31 March 2020

1 reference

Sall4 modulates embryonic stem cell pluripotency and early embryonic development by the transcriptional regulation of Pou5f1

31 March 2020

1 reference

Differentiation of embryonic stem cells is induced by GATA factors

31 March 2020

1 reference

Mammalian Grb2 regulates multiple steps in embryonic development and malignant transformation.

31 March 2020

1 reference

Targeted disruption of fibroblast growth factor (FGF) receptor 2 suggests a role for FGF signaling in pregastrulation mammalian development

31 March 2020

1 reference

Requirement of FGF-4 for postimplantation mouse development

31 March 2020

1 reference

Inactivation of the FGF-4 gene in embryonic stem cells alters the growth and/or the survival of their early differentiated progeny

31 March 2020

1 reference

Dynamic expression of Lrp2 pathway members reveals progressive epithelial differentiation of primitive endoderm in mouse blastocyst.

31 March 2020

1 reference

Asymmetric and node-specific nodal expression patterns are controlled by two distinct cis-acting regulatory elements

31 March 2020

1 reference

Nodal signalling in the epiblast patterns the early mouse embryo

31 March 2020

1 reference

Smad2 signaling in extraembryonic tissues determines anterior-posterior polarity of the early mouse embryo

31 March 2020

1 reference

Nodal antagonists in the anterior visceral endoderm prevent the formation of multiple primitive streaks

31 March 2020

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Disruption of early proximodistal patterning and AVE formation in Apc mutants

31 March 2020

1 reference

Requirement for beta-catenin in anterior-posterior axis formation in mice

31 March 2020

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Nodal protein processing and fibroblast growth factor 4 synergize to maintain a trophoblast stem cell microenvironment

31 March 2020

1 reference

Induction and migration of the anterior visceral endoderm is regulated by the extra-embryonic ectoderm.

31 March 2020

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Loss of the extraembryonic ectoderm in Elf5 mutants leads to defects in embryonic patterning

31 March 2020

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Ets2 is necessary in trophoblast for normal embryonic anteroposterior axis development.

31 March 2020

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Axis development and early asymmetry in mammals

31 March 2020

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From fertilization to gastrulation: axis formation in the mouse embryo.

31 March 2020

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Anterior primitive endoderm may be responsible for patterning the anterior neural plate in the mouse embryo

31 March 2020

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Cripto is required for correct orientation of the anterior-posterior axis in the mouse embryo

31 March 2020

1 reference

Crucial roles of Foxa2 in mouse anterior-posterior axis polarization via regulation of anterior visceral endoderm-specific genes

31 March 2020

1 reference

Nodal antagonists regulate formation of the anteroposterior axis of the mouse embryo

31 March 2020

1 reference

Active cell migration drives the unilateral movements of the anterior visceral endoderm

31 March 2020

1 reference

Axis specification and morphogenesis in the mouse embryo require Nap1, a regulator of WAVE-mediated actin branching

31 March 2020

1 reference

Canonical Wnt signaling and its antagonist regulate anterior-posterior axis polarization by guiding cell migration in mouse visceral endoderm

31 March 2020

1 reference

Origin of body axes in the mouse embryo

31 March 2020

1 reference

Multiple roles for Nodal in the epiblast of the mouse embryo in the establishment of anterior-posterior patterning

31 March 2020

1 reference

The type I activin receptor ActRIB is required for egg cylinder organization and gastrulation in the mouse

31 March 2020

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One-eyed pinhead regulates cell motility independent of Squint/Cyclops signaling

31 March 2020

1 reference

Bmpr encodes a type I bone morphogenetic protein receptor that is essential for gastrulation during mouse embryogenesis.

31 March 2020

1 reference

Combinatorial activities of Smad2 and Smad3 regulate mesoderm formation and patterning in the mouse embryo

31 March 2020

1 reference

Requirement for Wnt3 in vertebrate axis formation

31 March 2020

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The Wnt co-receptors Lrp5 and Lrp6 are essential for gastrulation in mice

31 March 2020

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The mouse Fused locus encodes Axin, an inhibitor of the Wnt signaling pathway that regulates embryonic axis formation

31 March 2020

1 reference

The nodal precursor acting via activin receptors induces mesoderm by maintaining a source of its convertases and BMP4.

31 March 2020

1 reference

Left-right asymmetric expression of lefty2 and nodal is induced by a signaling pathway that includes the transcription factor FAST2

31 March 2020

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Cell fate decisions within the mouse organizer are governed by graded Nodal signals

31 March 2020

1 reference

Integrating patterning signals: Wnt/GSK3 regulates the duration of the BMP/Smad1 signal

31 March 2020

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Bone morphogenetic protein-4 is required for mesoderm formation and patterning in the mouse

31 March 2020

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The endoderm of the mouse embryo arises by dynamic widespread intercalation of embryonic and extraembryonic lineages

31 March 2020

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Sonic hedgehog, a member of a family of putative signaling molecules, is implicated in the regulation of CNS polarity

31 March 2020

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Live imaging and genetic analysis of mouse notochord formation reveals regional morphogenetic mechanisms.

31 March 2020

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Differential requirements for Smad4 in TGFbeta-dependent patterning of the early mouse embryo

31 March 2020

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FoxH1 (Fast) functions to specify the anterior primitive streak in the mouse

31 March 2020

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The transcription factor FoxH1 (FAST) mediates Nodal signaling during anterior-posterior patterning and node formation in the mouse

31 March 2020

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Pivotal roles for eomesodermin during axis formation, epithelium-to-mesenchyme transition and endoderm specification in the mouse

31 March 2020

1 reference

A mechanism for the sharp transition of morphogen gradient interpretation in Xenopus

31 March 2020

1 reference

TGFbeta-SMAD signal transduction: molecular specificity and functional flexibility

31 March 2020

1 reference

Evolution of the mechanisms and molecular control of endoderm formation

31 March 2020

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Establishment of endoderm progenitors by SOX transcription factor expression in human embryonic stem cells

31 March 2020

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Regulation of the Xenopus Xsox17alpha(1) promoter by co-operating VegT and Sox17 sites

31 March 2020

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Development of definitive endoderm from embryonic stem cells in culture

31 March 2020

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Characterization of mesendoderm: a diverging point of the definitive endoderm and mesoderm in embryonic stem cell differentiation culture

31 March 2020

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Sox17 is essential for the specification of cardiac mesoderm in embryonic stem cells

31 March 2020

1 reference

Formation of multiple hearts in mice following deletion of beta-catenin in the embryonic endoderm

31 March 2020

1 reference

Epithelial-mesenchymal transition: at the crossroads of development and tumor metastasis

31 March 2020

1 reference

The transcription factor snail is a repressor of E-cadherin gene expression in epithelial tumour cells

31 March 2020

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The transcription factor snail controls epithelial-mesenchymal transitions by repressing E-cadherin expression

31 March 2020

1 reference

Targeted disruption of Fgf8 causes failure of cell migration in the gastrulating mouse embryo

31 March 2020

1 reference

FGF Signaling Regulates Mesoderm Cell Fate Specification and Morphogenetic Movement at the Primitive Streak

31 March 2020

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fgfr-1 is required for embryonic growth and mesodermal patterning during mouse gastrulation

31 March 2020

1 reference

The mouse snail gene encodes a key regulator of the epithelial-mesenchymal transition

31 March 2020

1 reference

p38 and a p38-interacting protein are critical for downregulation of E-cadherin during mouse gastrulation

31 March 2020

1 reference

Eomesodermin is required for mouse trophoblast development and mesoderm formation

31 March 2020

1 reference

Mesp1 acts as a master regulator of multipotent cardiovascular progenitor specification

31 March 2020

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Mesp1 coordinately regulates cardiovascular fate restriction and epithelial-mesenchymal transition in differentiating ESCs

31 March 2020

1 reference

SDF-1 alpha regulates mesendodermal cell migration during frog gastrulation

31 March 2020

1 reference

Sdf1/Cxcr4 signaling controls the dorsal migration of endodermal cells during zebrafish gastrulation.

31 March 2020

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Convergent extension: the molecular control of polarized cell movement during embryonic development

31 March 2020

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The amniote primitive streak is defined by epithelial cell intercalation before gastrulation.

31 March 2020

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Immune and nervous system CXCL12 and CXCR4: parallel roles in patterning and plasticity

31 March 2020

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High-throughput mapping of a dynamic signaling network in mammalian cells

31 March 2020

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Regulation of the polarity protein Par6 by TGFbeta receptors controls epithelial cell plasticity

31 March 2020

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TGF-beta signaling-mediated morphogenesis: modulation of cell adhesion via cadherin endocytosis

31 March 2020

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Ventral closure, headfold fusion and definitive endoderm migration defects in mouse embryos lacking the fibronectin leucine-rich transmembrane protein FLRT3

31 March 2020

1 reference

BMP signalling inhibits premature neural differentiation in the mouse embryo

31 March 2020

1 reference

Absence of Nodal signaling promotes precocious neural differentiation in the mouse embryo

31 March 2020

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Dkk1 and Wnt3 interact to control head morphogenesis in the mouse

31 March 2020

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Dickkopf1 is required for embryonic head induction and limb morphogenesis in the mouse

31 March 2020

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The organizer factors Chordin and Noggin are required for mouse forebrain development

31 March 2020

1 reference

Genome-wide identification of Smad/Foxh1 targets reveals a role for Foxh1 in retinoic acid regulation and forebrain development

31 March 2020

1 reference

Induction of the mammalian node requires Arkadia function in the extraembryonic lineages

31 March 2020

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Arkadia enhances nodal-related signalling to induce mesendoderm

31 March 2020

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Arkadia enhances Nodal/TGF-beta signaling by coupling phospho-Smad2/3 activity and turnover

31 March 2020

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A SMAD ubiquitin ligase targets the BMP pathway and affects embryonic pattern formation

31 March 2020

1 reference

Germ-layer specification and control of cell growth by Ectodermin, a Smad4 ubiquitin ligase

31 March 2020

1 reference

Pathway to totipotency: lessons from germ cells

31 March 2020

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Germ cell specification in mice

31 March 2020

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Bmp4 is required for the generation of primordial germ cells in the mouse embryo

31 March 2020

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Smad5 is required for mouse primordial germ cell development

31 March 2020

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Dose-dependent Smad1, Smad5 and Smad8 signaling in the early mouse embryo.

31 March 2020

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BMP signaling mediated by ALK2 in the visceral endoderm is necessary for the generation of primordial germ cells in the mouse embryo

31 March 2020

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Proximal visceral endoderm and extraembryonic ectoderm regulate the formation of primordial germ cell precursors

31 March 2020

1 reference

IFITM/Mil/Fragilis Family Proteins IFITM1 and IFITM3 Play Distinct Roles in Mouse Primordial Germ Cell Homing and Repulsion

31 March 2020

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Normal germ line establishment in mice carrying a deletion of the Ifitm/Fragilis gene family cluster

31 March 2020

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A molecular programme for the specification of germ cell fate in mice.

31 March 2020

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Dppa3 / Pgc7 / stella is a maternal factor and is not required for germ cell specification in mice

31 March 2020

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Extensive and orderly reprogramming of genome-wide chromatin modifications associated with specification and early development of germ cells in mice.

31 March 2020

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Complex genome-wide transcription dynamics orchestrated by Blimp1 for the specification of the germ cell lineage in mice

31 March 2020

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Gene expression dynamics during germline specification in mice identified by quantitative single-cell gene expression profiling.

31 March 2020

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Blimp1 is a critical determinant of the germ cell lineage in mice

31 March 2020

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The zinc finger transcriptional repressor Blimp1/Prdm1 is dispensable for early axis formation but is required for specification of primordial germ cells in the mouse

31 March 2020

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Critical function of Prdm14 for the establishment of the germ cell lineage in mice

31 March 2020

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Blimp1 regulates development of the posterior forelimb, caudal pharyngeal arches, heart and sensory vibrissae in mice.

31 March 2020

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Blimp1 defines a progenitor population that governs cellular input to the sebaceous gland

31 March 2020

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Epidermal terminal differentiation depends on B lymphocyte-induced maturation protein-1.

31 March 2020

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Blimp-1 orchestrates plasma cell differentiation by extinguishing the mature B cell gene expression program

31 March 2020

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Regulation and functions of Blimp-1 in T and B lymphocytes

31 March 2020

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Blimp1 associates with Prmt5 and directs histone arginine methylation in mouse germ cells.

31 March 2020

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Derivation of pluripotent epiblast stem cells from mammalian embryos

31 March 2020

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Promotion of trophoblast stem cell proliferation by FGF4

31 March 2020

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New cell lines from mouse epiblast share defining features with human embryonic stem cells

31 March 2020

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Cell and molecular regulation of the mouse blastocyst

31 March 2020

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31 March 2020

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Nodal signaling: developmental roles and regulation.

31 March 2020

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Wnt/beta-catenin signaling in development and disease

31 March 2020

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A primary requirement for nodal in the formation and maintenance of the primitive streak in the mouse

31 March 2020

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12 December 2020

HNF3beta and Lim1 interact in the visceral endoderm to regulate primitive streak formation and anterior-posterior polarity in the mouse embryo

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12 December 2020

Genetic dissection of nodal function in patterning the mouse embryo

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12 December 2020

MesP1 and MesP2 are essential for the development of cardiac mesoderm

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12 December 2020

Fate mapping the mouse embryo

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12 December 2020

Formation of the definitive endoderm in mouse is a Smad2-dependent process.

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12 December 2020

Clonal analysis of epiblast fate during germ layer formation in the mouse embryo.

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12 December 2020

The Foxh1-dependent autoregulatory enhancer controls the level of Nodal signals in the mouse embryo

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12 December 2020

MesP1 is expressed in the heart precursor cells and required for the formation of a single heart tube

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12 December 2020

Mesodermal patterning defect in mice lacking the Ste20 NCK interacting kinase (NIK).

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12 December 2020

Depletion of definitive gut endoderm in Sox17-null mutant mice

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12 December 2020

A targeted mouse Otx2 mutation leads to severe defects in gastrulation and formation of axial mesoderm and to deletion of rostral brain

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12 December 2020

The transcription factor HNF3beta is required in visceral endoderm for normal primitive streak morphogenesis

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12 December 2020

Complete dissipation of coherent clonal growth occurs before gastrulation in mouse epiblast.

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12 December 2020

Mouse embryos lacking Smad1 signals display defects in extra-embryonic tissues and germ cell formation

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12 December 2020

Nodal specifies embryonic visceral endoderm and sustains pluripotent cells in the epiblast before overt axial patterning

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12 December 2020

Otx2 is required for visceral endoderm movement and for the restriction of posterior signals in the epiblast of the mouse embryo

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12 December 2020

Clonal analysis of cell fate during gastrulation and early neurulation in the mouse

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12 December 2020

Misexpression of Cwnt8C in the mouse induces an ectopic embryonic axis and causes a truncation of the anterior neuroectoderm

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12 December 2020

Identifiers

DOI

10.1038/NRM2618

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Dimensions Publication ID

5 August 2017

1012483465

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