(Q33277105)

25 July 2017

title

Arkadia enhances Nodal/TGF-beta signaling by coupling phospho-Smad2/3 activity and turnover (English)

1 reference

25 July 2017

author name string

Konstantinos J Mavrakis

1

1 reference

25 July 2017

Rebecca L Andrew

2

1 reference

25 July 2017

Kian Leong Lee

3

1 reference

25 July 2017

Chariklia Petropoulou

4

1 reference

25 July 2017

James E Dixon

5

1 reference

25 July 2017

Naveenan Navaratnam

6

1 reference

25 July 2017

Dominic P Norris

7

1 reference

25 July 2017

Vasso Episkopou

8

1 reference

25 July 2017

language of work or name

English

0 references

publication date

1 March 2007

1 reference

25 July 2017

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25 July 2017

volume

5

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25 July 2017

issue

3

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25 July 2017

page(s)

e67

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Creative Commons Attribution 4.0 International

25 July 2017

copyright license

start time

6 March 2007

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

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PPM1A functions as a Smad phosphatase to terminate TGFbeta signaling

21 June 2018

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Absence of Nodal signaling promotes precocious neural differentiation in the mouse embryo

21 June 2018

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Axin is a scaffold protein in TGF-beta signaling that promotes degradation of Smad7 by Arkadia

21 June 2018

1 reference

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Smad transcription factors

21 June 2018

1 reference

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Specificity and versatility in tgf-beta signaling through Smads

21 June 2018

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Nodal stability determines signaling range.

21 June 2018

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Ski and SnoN: negative regulators of TGF-beta signaling

21 June 2018

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Combinatorial activities of Smad2 and Smad3 regulate mesoderm formation and patterning in the mouse embryo

21 June 2018

1 reference

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Regulation of the TGFbeta signalling pathway by ubiquitin-mediated degradation

21 June 2018

1 reference

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Nodal antagonists regulate formation of the anteroposterior axis of the mouse embryo

21 June 2018

1 reference

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Nucleocytoplasmic shuttling of signal transducers.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1808117

Arkadia amplifies TGF-beta superfamily signalling through degradation of Smad7

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1808117

Nodal Signaling in Vertebrate Development

21 June 2018

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Mechanisms of TGF-beta signaling from cell membrane to the nucleus

21 June 2018

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How the ubiquitin-proteasome system controls transcription

21 June 2018

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Extraembryonic proteases regulate Nodal signalling during gastrulation

21 June 2018

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Nodal antagonists in the anterior visceral endoderm prevent the formation of multiple primitive streaks

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1808117

Nodal activity in the node governs left-right asymmetry

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1808117

Nucleocytoplasmic shuttling of Smads 2, 3, and 4 permits sensing of TGF-beta receptor activity

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1808117

Smad2 nucleocytoplasmic shuttling by nucleoporins CAN/Nup214 and Nup153 feeds TGFbeta signaling complexes in the cytoplasm and nucleus

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1808117

The Foxh1-dependent autoregulatory enhancer controls the level of Nodal signals in the mouse embryo

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1808117

Emerging roles of ubiquitin in transcription regulation

21 June 2018

1 reference

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Smad regulation in TGF-beta signal transduction

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1808117

Ubiquitin enters the new millennium

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1808117

From fertilization to gastrulation: axis formation in the mouse embryo.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1808117

Nodal signalling in the epiblast patterns the early mouse embryo

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1808117

FoxH1 (Fast) functions to specify the anterior primitive streak in the mouse

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1808117

Arkadia enhances nodal-related signalling to induce mesendoderm

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1808117

Induction of the mammalian node requires Arkadia function in the extraembryonic lineages

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1808117

Defects of the body plan of mutant embryos lacking Lim1, Otx2 or Hnf3beta activity

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1808117

Themes and variations on ubiquitylation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1808117

Two-step regulation of left-right asymmetric expression of Pitx2: initiation by nodal signaling and maintenance by Nkx2.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1808117

The EGF-CFC gene family in vertebrate development.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1808117

The homeobox gene Hex is required in definitive endodermal tissues for normal forebrain, liver and thyroid formation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1808117

Nodal signalling in vertebrate development.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1808117

Ubiquitin-dependent degradation of TGF-beta-activated smad2.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1808117

c-Ski acts as a transcriptional co-repressor in transforming growth factor-beta signaling through interaction with smads

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1808117

Determination of left/right asymmetric expression of nodal by a left side-specific enhancer with sequence similarity to a lefty-2 enhancer

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1808117

Asymmetric and node-specific nodal expression patterns are controlled by two distinct cis-acting regulatory elements

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1808117

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1808117

Direct binding of Smad3 and Smad4 to critical TGF beta-inducible elements in the promoter of human plasminogen activator inhibitor-type 1 gene

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1808117

Smad2 signaling in extraembryonic tissues determines anterior-posterior polarity of the early mouse embryo

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1808117

The tumor suppressor SMAD4/DPC4 is essential for epiblast proliferation and mesoderm induction in mice

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1808117

The type I activin receptor ActRIB is required for egg cylinder organization and gastrulation in the mouse

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1808117

Cerberus-like is a secreted factor with neutralizing activity expressed in the anterior primitive endoderm of the mouse gastrula

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1808117

The tumor suppressor gene Smad4/Dpc4 is required for gastrulation and later for anterior development of the mouse embryo

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1808117

Relationship between asymmetric nodal expression and the direction of embryonic turning

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1808117

Induction of a second neural axis by the mouse node.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1808117

A primary requirement for nodal in the formation and maintenance of the primitive streak in the mouse

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1808117

Sonic hedgehog, a member of a family of putative signaling molecules, is implicated in the regulation of CNS polarity

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1808117

Responses of embryonic Xenopus cells to activin and FGF are separated by multiple dose thresholds and correspond to distinct axes of the mesoderm.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1808117

Diverse roles for ubiquitin-dependent proteolysis in transcriptional activation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1808117

Transcription. Proteasome parts at gene promoters

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1808117

Formation of the definitive endoderm in mouse is a Smad2-dependent process.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1808117

Anterior patterning in mouse.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1808117

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1808117

Left-right asymmetric expression of lefty2 and nodal is induced by a signaling pathway that includes the transcription factor FAST2

31 October 2018

1 reference

12 December 2020

The organizer of the mouse gastrula is composed of a dynamic population of progenitor cells for the axial mesoderm

1 reference

12 December 2020

Nkx-2.5: a novel murine homeobox gene expressed in early heart progenitor cells and their myogenic descendants

1 reference

12 December 2020

nodal expression in the primitive endoderm is required for specification of the anterior axis during mouse gastrulation

1 reference

12 December 2020

Nodal specifies embryonic visceral endoderm and sustains pluripotent cells in the epiblast before overt axial patterning

1 reference

12 December 2020

A new twist in Smad signaling

1 reference

12 December 2020

10.1371/JOURNAL.PBIO.0050067

Identifiers

DOI

1 reference

25 July 2017

1 reference

25 July 2017

1 reference