(Q34928737)

5 August 2017

1 reference

title

NNK-Induced Lung Tumors: A Review of Animal Model (English)

1 reference

5 August 2017

Hua-Chuan Zheng

1

1 reference

5 August 2017

Yasuo Takano

series ordinal

2

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5 August 2017

publication date

27 April 2011

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5 August 2017

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5 August 2017

volume

2011

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5 August 2017

page(s)

635379

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Creative Commons Attribution 3.0 Unported

5 August 2017

copyright license

start time

1 January 2011

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

1 reference

April 2022 Public Data File from Crossref

cites work

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Fish oil supplementation inhibits NNK-induced lung carcinogenesis in the A/J mouse

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Down-regulation of 14-3-3 isoforms and annexin A5 proteins in lung adenocarcinoma induced by the tobacco-specific nitrosamine NNK in the A/J mouse revealed by proteomic analysis

8 July 2018

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beta-Carotene promotes the development of NNK-induced small airway-derived lung adenocarcinoma

8 July 2018

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Effect of gefitinib on N-nitrosamine-4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone induced lung tumorigenesis in A/J mice

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Differential expression of microRNAs in early-stage neoplastic transformation in the lungs of F344 rats chronically treated with the tobacco carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone

8 July 2018

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8 July 2018

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Establishment of a bioassay model for lung cancer chemoprevention initiated with 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in female A/J mice.

8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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Array CGH analysis reveals chromosomal aberrations in mouse lung adenocarcinomas induced by the human lung carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone

8 July 2018

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9-cis-Retinoic acid inhibition of lung carcinogenesis in the A/J mouse model is accompanied by increased expression of RAR-beta but no change in cyclooxygenase-2.

8 July 2018

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Genetic polymorphism of CYP2A6 as one of the potential determinants of tobacco-related cancer risk

8 July 2018

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Phenethyl isothiocyanate and sulforaphane and their N-acetylcysteine conjugates inhibit malignant progression of lung adenomas induced by tobacco carcinogens in A/J mice.

8 July 2018

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8 July 2018

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Aberrant promoter hypermethylation of the death-associated protein kinase gene is early and frequent in murine lung tumors induced by cigarette smoke and tobacco carcinogens

8 July 2018

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Carcinogen exposure differentially modulates RAR-beta promoter hypermethylation, an early and frequent event in mouse lung carcinogenesis

8 July 2018

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Mechanisms of chronic disease causation by nutritional factors and tobacco products and their prevention by tea polyphenols

8 July 2018

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Chemopreventive efficacy of promising farnesyltransferase inhibitors

8 July 2018

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8 July 2018

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The role of CC10 in pulmonary carcinogenesis: from a marker to tumor suppression

8 July 2018

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The prevention of lung cancer induced by a tobacco-specific carcinogen in rodents by green and black Tea.

8 July 2018

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Reduced lung tumorigenesis in human methylguanine DNA--methyltransferase transgenic mice achieved by expression of transgene within the target cell.

8 July 2018

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Expression of cell cycle proteins in 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-induced mouse lung tumors

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3087887

The biological significance of tobacco-specific N-nitrosamines: smoking and adenocarcinoma of the lung

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3087887

Evaluation of the transplacental tumorigenicity of the tobacco-specific carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in mice

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3087887

Investigation of the role of lipoxygenase in bioactivation of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in human lung

8 July 2018

1 reference

https://api.crossref.org/works/10.1155%2F2011%2F635379

The effects of combined antioxidant (beta-carotene, alpha-tocopherol and ascorbic acid) supplementation on antioxidant capacity, DNA single-strand breaks and levels of insulin-like growth factor-1/IGF-binding protein 3 in the ferret model of lung ca

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2011%2F635379

Combined antioxidant (beta-carotene, alpha-tocopherol and ascorbic acid) supplementation increases the levels of lung retinoic acid and inhibits the activation of mitogen-activated protein kinase in the ferret lung cancer model

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2011%2F635379

Nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-induced pulmonary adenocarcinomas in Syrian golden hamsters contain beta 2-adrenergic receptor single-nucleotide polymorphisms.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2011%2F635379

Inhibitory effects of cinnamaldehyde on 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-induced lung carcinogenesis in rasH2 mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2011%2F635379

Carcinogen-specific targeting of chromosome 12 for loss of heterozygosity in mouse lung adenocarcinomas: implications for chromosome instability and tumor progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2011%2F635379

Transgenic mice overexpressing hepatocyte growth factor in the airways show increased susceptibility to lung cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2011%2F635379

The function of IGF-IR in NNK-mediated lung tumorigenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2011%2F635379

Mgmt deficiency alters the in vivo mutational spectrum of tissues exposed to the tobacco carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK).

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2011%2F635379

Enhancement of lung carcinogenesis initiated with 4-(N-hydroxymethylnitrosamino)-1-(3-pyridyl)-1-butanone by Ogg1 gene deficiency in female, but not male, mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2011%2F635379

Increased susceptibility of mice lacking Clara cell 10-kDa protein to lung tumorigenesis by 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone, a potent carcinogen in cigarette smoke

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2011%2F635379

Determination of the role of target tissue metabolism in lung carcinogenesis using conditional cytochrome P450 reductase-null mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2011%2F635379

Angiotensin II type 2 receptor gene deficiency attenuates susceptibility to tobacco-specific nitrosamine-induced lung tumorigenesis: involvement of transforming growth factor-beta-dependent cell growth attenuation

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2011%2F635379

The organoselenium compound 1,4-phenylenebis(methylene)selenocyanate inhibits 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-induced tumorgenesis and enhances glutathione-related antioxidant levels in A/J mouse lung.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2011%2F635379

Comparison of the chemopreventive efficacies of 1,4-phenylenebis(methylene)selenocyanate and selenium-enriched yeast on 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone induced lung tumorigenesis in A/J mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2011%2F635379

Chemopreventive activity of selenocysteine prodrugs against tobacco-derived nitrosamine (NNK) induced lung tumors in the A/J mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2011%2F635379

Inhibition of lung carcinogenesis and effects on angiogenesis and apoptosis in A/J mice by oral administration of green tea.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2011%2F635379

Inhibition of adenoma progression to adenocarcinoma in a 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-induced lung tumorigenesis model in A/J mice by tea polyphenols and caffeine.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2011%2F635379

The suppression of ornithine decarboxylase expression and cell proliferation at the promotion stage of lung tumorigenesis in mice by alpha-tocopheryloxybutyric acid

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2011%2F635379

Inhibition of lung carcinogenesis by 1alpha,25-dihydroxyvitamin D3 and 9-cis retinoic acid in the A/J mouse model: evidence of retinoid mitigation of vitamin D toxicity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2011%2F635379

Chemopreventive effects of deguelin, a novel Akt inhibitor, on tobacco-induced lung tumorigenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2011%2F635379

Antiproliferative and chemopreventive effects of adlay seed on lung cancer in vitro and in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2011%2F635379

Inhibitory effects of 7-hydroxy-3-methoxy-cadalene on 4-(methylinitrosamino)-1-(3-pyridyl)-1-butanone (NNK)-induced lung tumorigenesis in A/J mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2011%2F635379

Chemopreventive effect of kava on 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone plus benzo[a]pyrene-induced lung tumorigenesis in A/J mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2011%2F635379

Chemoprevention of lung cancer by isothiocyanates and their conjugates in A/J mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2011%2F635379

Inhibitory effect of mandarin juice rich in beta-cryptoxanthin and hesperidin on 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-induced pulmonary tumorigenesis in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2011%2F635379

K-ras mutations in lung tumors from A/J and A/J×TSG-p53 F1 mice treated with 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and phenethyl isothiocyanate

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2011%2F635379

Detection of overexpressed COX-2 in precancerous lesions of hamster pancreas and lungs by molecular imaging: implications for early diagnosis and prevention.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2011%2F635379

High oleic acid oil suppresses lung tumorigenesis in mice through the modulation of extracellular signal-regulated kinase cascade

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2011%2F635379

The effects of dietary myoinositol on lung tumor development in tobacco smoke-exposed mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2011%2F635379

Identification of a highly effective rapamycin schedule that markedly reduces the size, multiplicity, and phenotypic progression of tobacco carcinogen-induced murine lung tumors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2011%2F635379

Prevention of mouse lung tumors by targretin

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2011%2F635379

Chemopreventive effects of fermented brown rice and rice bran against 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-induced lung tumorigenesis in female A/J mice

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3087887

Lack of modifying potential of 8-methoxypsoralen in the promotion or progression stages of lung carcinogenesis in A/J female mice

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3087887

Pretreatment with 8-methoxypsoralen, a potent human CYP2A6 inhibitor, strongly inhibits lung tumorigenesis induced by 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in female A/J mice.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3087887

Chemopreventive efficacy of suberoylanilide hydroxamic acid (SAHA) against 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK)-induced lung tumorigenesis in female A/J mice.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3087887

Increased susceptibility to the tobacco carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in transgenic mice overexpressing c-myc and epidermal growth factor in alveolar type II cells

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3087887

Chemoprevention of lung tumorigenesis induced by a mixture of benzo(a)pyrene and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone by the organoselenium compound 1,4-phenylenebis(methylene)selenocyanate

26 October 2018

1 reference

12 December 2020

Inhibition of COX-2 and induction of apoptosis: two determinants of nonsteroidal anti-inflammatory drugs' chemopreventive efficacies in mouse lung tumorigenesis

1 reference

12 December 2020

Role of the alveolar type II cell in the development and progression of pulmonary tumors induced by 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in the A/J mouse

1 reference

12 December 2020

The tobacco-specific carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone is a beta-adrenergic agonist and stimulates DNA synthesis in lung adenocarcinoma via beta-adrenergic receptor-mediated release of arachidonic acid

1 reference

12 December 2020

Point mutation of K-ras gene in cisplatin-induced lung tumours in A/J mice

1 reference

12 December 2020

The inhibitory effect of vitamin E on 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-induced DNA injury and the fixation of the DNA injury in mouse lungs

1 reference

12 December 2020

Effects of protocatechuic acid, S-methylmethanethiosulfonate or 5-hydroxy-4-(2-phenyl-(E)ethenyl)-2(5H)-furanone(KYN-54) on 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-induced pulmonary carcinogenesis in mice

1 reference

12 December 2020

Chemopreventive effect of saponins derived from roots of Platycodon grandiflorum on 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-induced lung tumorigenesis in A/J mice

1 reference

12 December 2020

The inhibitory effect of vitamin E on 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-induced lung tumorigenesis in mice based on the regulation of polyamine metabolism

1 reference

12 December 2020

Indole-3-carbinol inhibits 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone plus benzo(a)pyrene-induced lung tumorigenesis in A/J mice and modulates carcinogen-induced alterations in protein levels

1 reference

12 December 2020

Inhaled isotretinoin (13-cis retinoic acid) is an effective lung cancer chemopreventive agent in A/J mice at low doses: a pilot study

1 reference

12 December 2020

Identifiers

DOI

10.1155/2011/635379

1 reference

5 August 2017

1 reference

5 August 2017

1 reference