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Angiogenesis in ischemic and neoplastic disorders

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Europe PubMed Central

5 August 2017

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Europe PubMed Central

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Angiogenesis in ischemic and neoplastic disorders (English)

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Europe PubMed Central

5 August 2017

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1

Gregg L Semenza

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Europe PubMed Central

PubMed ID

12359828

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5 August 2017

language of work or name

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3 December 2001

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Europe PubMed Central

5 August 2017

Annual Review of Medicine

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Europe PubMed Central

5 August 2017

54

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Europe PubMed Central

5 August 2017

17-28

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Europe PubMed Central

5 August 2017

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Cardiac hypertrophy in chronically anemic fetal sheep: Increased vascularization is associated with increased myocardial expression of vascular endothelial growth factor and hypoxia-inducible factor 1

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Growth factors acting via endothelial cell-specific receptor tyrosine kinases: VEGFs, angiopoietins, and ephrins in vascular development

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Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension

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Therapeutic interventions for enhancing collateral development by administration of growth factors: basic principles, early results and potential hazards

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Drilling for oxygen: angiogenesis involves proteolysis of the extracellular matrix

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Coronary collateral development in swine after coronary artery occlusion

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Surviving ischemia: adaptive responses mediated by hypoxia-inducible factor 1

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Genetic heterogeneity of angiogenesis in mice.

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Requisite role of angiopoietin-1, a ligand for the TIE2 receptor, during embryonic angiogenesis

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Effect of p53 status on tumor response to antiangiogenic therapy.

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Age-dependent impairment of angiogenesis

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Angiopoietin-2, a natural antagonist for Tie2 that disrupts in vivo angiogenesis

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Pericyte loss and microaneurysm formation in PDGF-B-deficient mice

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Upregulation of vascular endothelial growth factor expression induced by myocardial ischaemia: implications for coronary angiogenesis

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PR39, a peptide regulator of angiogenesis

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Targeting of HIF-alpha to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation

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Continuous low-dose therapy with vinblastine and VEGF receptor-2 antibody induces sustained tumor regression without overt toxicity

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Building better vasculature

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Expression of hypoxia-inducible factor-1 alpha in oligodendrogliomas: its impact on prognosis and on neoangiogenesis.

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Synergism between vascular endothelial growth factor and placental growth factor contributes to angiogenesis and plasma extravasation in pathological conditions.

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Induction of hypervascularity without leakage or inflammation in transgenic mice overexpressing hypoxia-inducible factor-1alpha

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Interindividual heterogeneity in the hypoxic regulation of VEGF: significance for the development of the coronary artery collateral circulation

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C. elegans EGL-9 and mammalian homologs define a family of dioxygenases that regulate HIF by prolyl hydroxylation

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Early expression of angiogenesis factors in acute myocardial ischemia and infarction

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Antiangiogenic therapy of experimental cancer does not induce acquired drug resistance.

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Myocardial gene therapy

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The function of hypoxia-inducible factor 1 (HIF-1) is impaired in senescent mice

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Age-dependent defect in vascular endothelial growth factor expression is associated with reduced hypoxia-inducible factor 1 activity

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Heterozygous embryonic lethality induced by targeted inactivation of the VEGF gene

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A conserved family of prolyl-4-hydroxylases that modify HIF

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HIFalpha targeted for VHL-mediated destruction by proline hydroxylation: implications for O2 sensing

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Levels of hypoxia-inducible factor-1 alpha during breast carcinogenesis

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Tumor hypoxia: definitions and current clinical, biologic, and molecular aspects

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Inducer-stimulated Fas targets activated endothelium for destruction by anti-angiogenic thrombospondin-1 and pigment epithelium-derived factor

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10.1146/ANNUREV.MED.54.101601.152418

1 reference

stated in

Europe PubMed Central

5 August 2017

1 reference

Europe PubMed Central

PubMed ID

12359828

retrieved

5 August 2017

(Q34931041)

Angiogenesis in ischemic and neoplastic disorders

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