(Q34931100)

5 August 2017

title

Alteration of thioredoxin reductase 1 levels in elucidating cancer etiology (English)

1 reference

5 August 2017

5

Vadim N Gladyshev

1 reference

5 August 2017

2

Bradley A Carlson

1 reference

5 August 2017

6

Dolph L Hatfield

1 reference

5 August 2017

1

Min-Hyuk Yoo

1 reference

5 August 2017

3

Petra Tsuji

1 reference

5 August 2017

Robert Irons

4

1 reference

5 August 2017

language of work or name

English

0 references

publication date

20 June 2010

1 reference

5 August 2017

published in

Methods in Enzymology

1 reference

5 August 2017

volume

474

1 reference

5 August 2017

page(s)

255-275

1 reference

describes a project that uses

5 August 2017

ImageQuant

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3088101/fullTextXML

inferred from PubMed Central ID database lookup

cites work

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Thioredoxin reductase 1 ablation sensitizes colon cancer cells to methylseleninate-mediated cytotoxicity

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High levels of thioredoxin reductase 1 modulate drug-specific cytotoxic efficacy

8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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Potent activity of indolequinones against human pancreatic cancer: identification of thioredoxin reductase as a potential target

8 July 2018

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Focus on mammalian thioredoxin reductases--important selenoproteins with versatile functions

8 July 2018

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Adiponectin haploinsufficiency promotes mammary tumor development in MMTV-PyVT mice by modulation of phosphatase and tensin homolog activities

8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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Thioredoxin reductase-1 knock down does not result in thioredoxin-1 oxidation

8 July 2018

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Targeting thioredoxin reductase 1 reduction in cancer cells inhibits self-sufficient growth and DNA replication

8 July 2018

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Selenium as an anticancer nutrient: roles in cell proliferation and tumor cell invasion

8 July 2018

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A new strategy for assessing selenoprotein function: siRNA knockdown/knock-in targeting the 3'-UTR.

8 July 2018

1 reference

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8 July 2018

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8 July 2018

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8 July 2018

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Selenoprotein deficiency accelerates prostate carcinogenesis in a transgenic model

8 July 2018

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Thioredoxin reductase 1 deficiency reverses tumor phenotype and tumorigenicity of lung carcinoma cells

8 July 2018

1 reference

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Human selenoproteins at a glance

8 July 2018

1 reference

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Cytoplasmic thioredoxin reductase is essential for embryogenesis but dispensable for cardiac development

8 July 2018

1 reference

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The thioredoxin reductase/thioredoxin system: novel redox targets for cancer therapy

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3088101

Regulation of the mammalian selenoprotein thioredoxin reductase 1 in relation to cellular phenotype, growth, and signaling events.

8 July 2018

1 reference

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Electrophilic prostaglandins and lipid aldehydes repress redox-sensitive transcription factors p53 and hypoxia-inducible factor by impairing the selenoprotein thioredoxin reductase

8 July 2018

1 reference

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SECIS-SBP2 interactions dictate selenocysteine incorporation efficiency and selenoprotein hierarchy

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3088101

Physiological functions of thioredoxin and thioredoxin reductase

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3088101

Essential role of selenium in the catalytic activities of mammalian thioredoxin reductase revealed by characterization of recombinant enzymes with selenocysteine mutations

8 July 2018

1 reference

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8 July 2018

The Hallmarks of Cancer

1 reference

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Rat and calf thioredoxin reductase are homologous to glutathione reductase with a carboxyl-terminal elongation containing a conserved catalytically active penultimate selenocysteine residue.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3088101

Selenocysteine, identified as the penultimate C-terminal residue in human T-cell thioredoxin reductase, corresponds to TGA in the human placental gene

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3088101

Flat revertants isolated from Kirsten sarcoma virus-transformed cells are resistant to the action of specific oncogenes

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3088101

Cinnamaldehydes inhibit thioredoxin reductase and induce Nrf2: potential candidates for cancer therapy and chemoprevention

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3088101

Selenium and vitamin E supplementation for cancer prevention

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3088101

Both selenoproteins and low molecular weight selenocompounds reduce colon cancer risk in mice with genetically impaired selenoprotein expression

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3088101

Evidence for intriguingly complex transcription of human thioredoxin reductase 1.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3088101

Thioredoxin reductase in human hepatoma cells is transcriptionally regulated by sulforaphane and other electrophiles via an antioxidant response element

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3088101

High-throughput 96-well microplate assays for determining specific activities of glutathione peroxidase and thioredoxin reductase

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3088101

Determination of thioredoxin reductase activity in rat liver supernatant

26 October 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2810%2974015-5

7 January 2021

Thioredoxin and thioredoxin reductase

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2810%2974015-5

7 January 2021

Thioredoxin reductase 1 upregulates MCP-1 release in human endothelial cells

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2810%2974015-5

7 January 2021

Mammalian thioredoxin reductase is irreversibly inhibited by dinitrohalobenzenes by alkylation of both the redox active selenocysteine and its neighboring cysteine residue

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2810%2974015-5

7 January 2021

The human p53 negative regulatory domain mediates inhibition of reporter gene transactivation in yeast lacking thioredoxin reductase

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20609915

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1016/S0076-6879(10)74015-5

1 reference

5 August 2017

1 reference

5 August 2017

1 reference