(Q34942847)

5 August 2017

1 reference

title

Chemokines, chemokine receptors and small-molecule antagonists: recent developments (English)

1 reference

5 August 2017

James J Onuffer

1

1 reference

PubMed ID

12368070

5 August 2017

Richard Horuk

series ordinal

2

1 reference

5 August 2017

1 October 2002

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Trends in Pharmacological Sciences

5 August 2017

1 reference

5 August 2017

23

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5 August 2017

10

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5 August 2017

459-467

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Modelling G-protein-coupled receptors for drug design

5 August 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2902064-3

7 January 2021

Crystal structure of rhodopsin: A G protein-coupled receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2902064-3

7 January 2021

The ligands of CXC chemokine receptor 3, I-TAC, Mig, and IP10, are natural antagonists for CCR3

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2902064-3

7 January 2021

The CC chemokine eotaxin (CCL11) is a partial agonist of CC chemokine receptor 2b.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2902064-3

7 January 2021

Eotaxin is a natural antagonist for CCR2 and an agonist for CCR5

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2902064-3

7 January 2021

Extension of recombinant human RANTES by the retention of the initiating methionine produces a potent antagonist.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2902064-3

7 January 2021

Amino-terminally modified RANTES analogues demonstrate differential effects on RANTES receptors

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2902064-3

7 January 2021

Differential activation of CC chemokine receptors by AOP-RANTES

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2902064-3

7 January 2021

Kinetic investigation of chemokine truncation by CD26/dipeptidyl peptidase IV reveals a striking selectivity within the chemokine family

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2902064-3

7 January 2021

Urokinase plasminogen activator and plasmin efficiently convert hemofiltrate CC chemokine 1 into its active

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2902064-3

7 January 2021

Diverging binding capacities of natural LD78beta isoforms of macrophage inflammatory protein-1alpha to the CC chemokine receptors 1, 3 and 5 affect their anti-HIV-1 activity and chemotactic potencies for neutrophils and eosinophils

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2902064-3

7 January 2021

Attractin: a cub-family protease involved in T cell-monocyte/macrophage interactions

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2902064-3

7 January 2021

CD26, let it cut or cut it down.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2902064-3

7 January 2021

The Role of CD26/DPP IV in Chemokine Processing

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2902064-3

7 January 2021

Fractalkine shares signal sequence with TARC: gene structures and expression profiles of two chemokine genes

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2902064-3

7 January 2021

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2902064-3

1 reference

7 January 2021

Chemokines in pathology and medicine

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2902064-3

7 January 2021

Chemokine receptor antagonists

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2902064-3

7 January 2021

The strategy of blocking the chemokine system to combat disease

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2902064-3

7 January 2021

Identification of the binding site for a novel class of CCR2b chemokine receptor antagonists: binding to a common chemokine receptor motif within the helical bundle

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2902064-3

7 January 2021

A binding pocket for a small molecule inhibitor of HIV-1 entry within the transmembrane helices of CCR5

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2902064-3

7 January 2021

Molecular interactions of cyclam and bicyclam non-peptide antagonists with the CXCR4 chemokine receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2902064-3

7 January 2021

Mutation of Asp(171) and Asp(262) of the chemokine receptor CXCR4 impairs its coreceptor function for human immunodeficiency virus-1 entry and abrogates the antagonistic activity of AMD3100.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2902064-3

7 January 2021

A small molecule antagonist of chemokine receptors CCR1 and CCR3. Potent inhibition of eosinophil function and CCR3-mediated HIV-1 entry.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2902064-3

7 January 2021

Novel low molecular weight spirodiketopiperazine derivatives potently inhibit R5 HIV-1 infection through their antagonistic effects on CCR5.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2902064-3

7 January 2021

The second extracellular loop of CCR5 is the major determinant of ligand specificity.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2902064-3

7 January 2021

Species selectivity of a small molecule antagonist for the CCR1 chemokine receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2902064-3

7 January 2021

Piperazine-based CCR5 antagonists as HIV-1 inhibitors. I: 2(S)-methyl piperazine as a key pharmacophore element

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2902064-3

7 January 2021

CCR2B receptor antagonists: conversion of a weak HTS hit to a potent lead compound

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2902064-3

7 January 2021

Identification and characterization of small molecule functional antagonists of the CCR1 chemokine receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2902064-3

7 January 2021

Granulocyte-macrophage colony stimulating factor up-regulates CCR1 in human neutrophils

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2902064-3

7 January 2021

Analysis of fractalkine receptor CX(3)CR1 function by targeted deletion and green fluorescent protein reporter gene insertion

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2902064-3

7 January 2021

Expression and characterization of the chemokine receptors CCR2 and CCR5 in mice

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2902064-3

7 January 2021

Lack of chemokine receptor CCR1 enhances Th1 responses and glomerular injury during nephrotoxic nephritis

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2902064-3

7 January 2021

Epitope mapping of CCR5 reveals multiple conformational states and distinct but overlapping structures involved in chemokine and coreceptor function

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2902064-3

7 January 2021

Multiple active states and oligomerization of CCR5 revealed by functional properties of monoclonal antibodies

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2902064-3

7 January 2021

Antigenically distinct conformations of CXCR4.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2902064-3

7 January 2021

Pharmacological evidence for complex and multiple site interaction of CXCR4 with SDF-1alpha: implications for development of selective CXCR4 antagonists

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2902064-3

7 January 2021

Human interferon-inducible 10-kDa protein and human interferon-inducible T cell alpha chemoattractant are allotopic ligands for human CXCR3: differential binding to receptor states.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2902064-3

7 January 2021

Allosteric regulation of CCR5 by guanine nucleotides and HIV-1 envelope

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2902064-3

7 January 2021

Molecular function of the CD4 D1 domain in coreceptor-mediated entry by HIV type 1.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2902064-3

7 January 2021

Comodulation of CXCR4 and CD26 in human lymphocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2902064-3

7 January 2021

An anti-inflammatory drug, propagermanium, may target GPI-anchored proteins associated with an MCP-1 receptor, CCR2.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2902064-3

7 January 2021

10.1016/S0165-6147(02)02064-3

Identifiers

DOI

1 reference

5 August 2017

1 reference

PubMed ID

12368070