(Q34943864)

English

Location of the antidepressant binding site in the serotonin transporter: importance of Ser-438 in recognition of citalopram and tricyclic antidepressants.

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scholarly article

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19213730%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

Location of the antidepressant binding site in the serotonin transporter: importance of Ser-438 in recognition of citalopram and tricyclic antidepressants (English)

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19213730%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

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1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19213730%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

Kasper B. Hansen

3

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19213730%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

Kristian Strømgaard

6

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19213730%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

Anders Skov Kristensen

7

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Europe PubMed Central

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21 January 2020

author name string

Olivier Taboureau

2

1 reference

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21 January 2020

Lars Olsen

4

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19213730%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

Jan Egebjerg

5

1 reference

Europe PubMed Central

PMC publication ID

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21 January 2020

language of work or name

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publication date

12 February 2009

1 reference

Europe PubMed Central

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21 January 2020

number of pages

9

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based on heuristic

inferred from page(s)

Journal of Biological Chemistry

1 reference

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21 January 2020

284

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21 January 2020

15

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Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19213730%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

10276-10284

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19213730%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

A competitive inhibitor traps LeuT in an open-to-out conformation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2665081

8 July 2018

The binding sites for cocaine and dopamine in the dopamine transporter overlap

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2665081

8 July 2018

Binding of serotonin to the human serotonin transporter. Molecular modeling and experimental validation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2665081

8 July 2018

Bound to be different: neurotransmitter transporters meet their bacterial cousins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2665081

8 July 2018

What is an antidepressant binding site doing in a bacterial transporter?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2665081

8 July 2018

Mechanism of chloride interaction with neurotransmitter:sodium symporters.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2665081

8 July 2018

LeuT-desipramine structure reveals how antidepressants block neurotransmitter reuptake

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2665081

8 July 2018

Antidepressant binding site in a bacterial homologue of neurotransmitter transporters

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2665081

8 July 2018

Identification of a chloride ion binding site in Na+/Cl -dependent transporters.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2665081

8 July 2018

Serotonin transporters--structure and function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2665081

8 July 2018

Getting the message across: a recent transporter structure shows the way.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2665081

8 July 2018

Tyr-95 and Ile-172 in transmembrane segments 1 and 3 of human serotonin transporters interact to establish high affinity recognition of antidepressants

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2665081

8 July 2018

Case history: the discovery of fluoxetine hydrochloride (Prozac)

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2665081

8 July 2018

Crystal structure of a bacterial homologue of Na+/Cl--dependent neurotransmitter transporters

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2665081

8 July 2018

Cysteine-scanning mutagenesis of serotonin transporter intracellular loop 2 suggests an alpha-helical conformation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2665081

8 July 2018

The chicken serotonin transporter discriminates between serotonin-selective reuptake inhibitors. A species-scanning mutagenesis study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2665081

8 July 2018

Glide: a new approach for rapid, accurate docking and scoring. 2. Enrichment factors in database screening

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2665081

8 July 2018

Glide: a new approach for rapid, accurate docking and scoring. 1. Method and assessment of docking accuracy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2665081

8 July 2018

Modeller: generation and refinement of homology-based protein structure models

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2665081

8 July 2018

Species-scanning mutagenesis of the serotonin transporter reveals residues essential in selective, high-affinity recognition of antidepressants

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2665081

8 July 2018

Interactions of tryptamine derivatives with serotonin transporter species variants implicate transmembrane domain I in substrate recognition

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2665081

8 July 2018

Characteristics of drug interactions with recombinant biogenic amine transporters expressed in the same cell type

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2665081

8 July 2018

Pharmacological profile of antidepressants and related compounds at human monoamine transporters

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2665081

8 July 2018

Neurotransmitter receptor and transporter binding profile of antidepressants and their metabolites

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2665081

8 July 2018

A single serine residue controls the cation dependence of substrate transport by the rat serotonin transporter

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2665081

8 July 2018

Relationship between the inhibition constant (K1) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2665081

8 July 2018

Single-site model of the neuronal 5-hydroxytryptamine uptake and imipramine-binding site.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2665081

8 July 2018

Dopamine transporter site-directed mutations differentially alter substrate transport and cocaine binding

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2665081

8 July 2018

The molecular mechanism of "ecstasy" [3,4-methylenedioxy-methamphetamine (MDMA)]: serotonin transporters are targets for MDMA-induced serotonin release

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2665081

8 July 2018

Mechanism of imipramine inhibition of platelet 5-hydroxytryptamine transport

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2665081

8 July 2018

Molecular basis for substrate discrimination by glycine transporters

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M806907200

21 January 2018

Selective amino acid substitutions convert the creatine transporter to a gamma-aminobutyric acid transporter.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M806907200

21 January 2018

Mutational scanning of the human serotonin transporter reveals fast translocating serotonin transporter mutants

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M806907200

21 January 2018

High affinity recognition of serotonin transporter antagonists defined by species-scanning mutagenesis. An aromatic residue in transmembrane domain I dictates species-selective recognition of citalopram and mazindol

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M806907200

21 January 2018

The mechanism of a neurotransmitter:sodium symporter--inward release of Na+ and substrate is triggered by substrate in a second binding site

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M806907200

21 January 2018

Transmembrane domain I contributes to the permeation pathway for serotonin and ions in the serotonin transporter.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2665081

26 October 2018

Serotonin modulates the dissociation of [3H]imipramine from human platelet recognition sites

1 reference

https://pubmed.ncbi.nlm.nih.gov/19213730

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The serotonin transporter-imipramine "receptor"

1 reference

https://pubmed.ncbi.nlm.nih.gov/19213730

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antidepressant binding to the porcine and human platelet serotonin transporters

1 reference

https://pubmed.ncbi.nlm.nih.gov/19213730

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A common binding site for tricyclic and nontricyclic 5-hydroxytryptamine uptake inhibitors at the substrate recognition site of the neuronal sodium-dependent 5-hydroxytryptamine transporter

1 reference

https://pubmed.ncbi.nlm.nih.gov/19213730

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of a single amino acid, phenylalanine 586, that is responsible for high affinity interactions of tricyclic antidepressants with the human serotonin transporter

1 reference

https://pubmed.ncbi.nlm.nih.gov/19213730

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A comprehensive structure-based alignment of prokaryotic and eukaryotic neurotransmitter/Na+ symporters (NSS) aids in the use of the LeuT structure to probe NSS structure and function

1 reference

https://pubmed.ncbi.nlm.nih.gov/19213730

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1074/JBC.M806907200

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19213730%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19213730%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19213730%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

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