(Q40354350)

English

Tyr-95 and Ile-172 in transmembrane segments 1 and 3 of human serotonin transporters interact to establish high affinity recognition of antidepressants

scientific article published on 3 November 2005

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scholarly article

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Europe PubMed Central

PubMed publication ID

19 September 2017

Tyr-95 and Ile-172 in transmembrane segments 1 and 3 of human serotonin transporters interact to establish high affinity recognition of antidepressants (English)

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Europe PubMed Central

PubMed publication ID

19 September 2017

transmembrane protein

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Amy Hauck Newman

7

object named as

Amy H Newman

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Europe PubMed Central

PubMed publication ID

19 September 2017

author name string

L Keith Henry

1

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Europe PubMed Central

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19 September 2017

Julie R Field

2

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Europe PubMed Central

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19 September 2017

Erika M Adkins

3

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Europe PubMed Central

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19 September 2017

M Laura Parnas

4

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Europe PubMed Central

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19 September 2017

Roxanne A Vaughan

5

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19 September 2017

Mu-Fa Zou

6

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19 September 2017

Randy D Blakely

8

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19 September 2017

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publication date

3 November 2005

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19 September 2017

number of pages

12

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Journal of Biological Chemistry

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19 September 2017

281

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19 September 2017

4

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19 September 2017

2012-2023

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19 September 2017

Antidepressant- and cocaine-sensitive human serotonin transporter: molecular cloning, expression, and chromosomal localization

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M505055200

21 January 2018

The membrane-bound rat serotonin transporter, SERT1, is an oligomeric protein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M505055200

21 January 2018

Oligomerization of serotonin transporter and its functional consequences

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M505055200

21 January 2018

Serotonin transporter function and pharmacology are sensitive to expression level: evidence for an endogenous regulatory factor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M505055200

21 January 2018

Preservation and staining of myelinated nerve fibers.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M505055200

21 January 2018

Serotonin and cocaine-sensitive inactivation of human serotonin transporters by methanethiosulfonates targeted to transmembrane domain I.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M505055200

21 January 2018

Species-scanning mutagenesis of the serotonin transporter reveals residues essential in selective, high-affinity recognition of antidepressants

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M505055200

21 January 2018

The chicken serotonin transporter discriminates between serotonin-selective reuptake inhibitors. A species-scanning mutagenesis study

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M505055200

21 January 2018

High affinity recognition of serotonin transporter antagonists defined by species-scanning mutagenesis. An aromatic residue in transmembrane domain I dictates species-selective recognition of citalopram and mazindol

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M505055200

21 January 2018

Advanced mammalian gene transfer: high titre retroviral vectors with multiple drug selection markers and a complementary helper-free packaging cell line

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M505055200

21 January 2018

Uptake inhibitors but not substrates induce protease resistance in extracellular loop two of the dopamine transporter

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M505055200

21 January 2018

Dopamine transporter ligand binding domains. Structural and functional properties revealed by limited proteolysis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M505055200

21 January 2018

Permeation and gating residues in serotonin transporter

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M505055200

21 January 2018

Novel tropane-based irreversible ligands for the dopamine transporter

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M505055200

21 January 2018

Affinity labeling the dopamine transporter ligand binding site

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M505055200

21 January 2018

Structural determinants of neurotransmitter transport using cross-species chimeras: studies on serotonin transporter.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M505055200

21 January 2018

3H cocaine labels a binding site associated with the serotonin transporter in guinea pig brain: allosteric modulation by paroxetine

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M505055200

21 January 2018

Proximity of transmembrane domains 1 and 3 of the gamma-aminobutyric acid transporter GAT-1 inferred from paired cysteine mutagenesis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M505055200

21 January 2018

Oligomerization of the {gamma}-aminobutyric acid transporter-1 is driven by an interplay of polar and hydrophobic interactions in transmembrane helix II

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M505055200

21 January 2018

Escitalopram, the S-(+)-enantiomer of citalopram, is a selective serotonin reuptake inhibitor with potent effects in animal models predictive of antidepressant and anxiolytic activities

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M505055200

21 January 2018

Second-generation SSRIs: human monoamine transporter binding profile of escitalopram and R-fluoxetine

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M505055200

21 January 2018

Molecular mechanism of citalopram and cocaine interactions with neurotransmitter transporters

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M505055200

21 January 2018

Binding and transport in norepinephrine transporters. Real-time, spatially resolved analysis in single cells using a fluorescent substrate

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M505055200

21 January 2018

Defining proximity relationships in the tertiary structure of the dopamine transporter. Identification of a conserved glutamic acid as a third coordinate in the endogenous Zn(2+)-binding site.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M505055200

21 January 2018

The region of dopamine transporter encompassing the 3rd transmembrane domain is crucial for function

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M505055200

21 January 2018

Crystal structure of a bacterial homologue of Na+/Cl--dependent neurotransmitter transporters

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M505055200

21 January 2018

Identifiers

10.1074/JBC.M505055200

1 reference

Europe PubMed Central

PubMed publication ID

19 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

19 September 2017

ResearchGate publication ID

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