(Q34946215)

5 August 2017

title

MEK5/ERK5 signaling suppresses estrogen receptor expression and promotes hormone-independent tumorigenesis (English)

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5 August 2017

10

Lyndsay V Rhodes

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5 August 2017

Bin Shan

14

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Kenneth P Nephew

16

object named as

Kenneth P Nephew

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5 August 2017

James W Antoon

1

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5 August 2017

Elizabeth C Martin

2

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5 August 2017

Rongye Lai

3

1 reference

5 August 2017

Virgilo A Salvo

4

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5 August 2017

Yan Tang

5

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5 August 2017

Ashley M Nitzchke

6

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5 August 2017

Steven Elliott

7

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5 August 2017

Seung Yoon Nam

8

1 reference

5 August 2017

Wei Xiong

9

1 reference

5 August 2017

Bridgette Collins-Burow

11

1 reference

5 August 2017

Odile David

12

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5 August 2017

Guandi Wang

13

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5 August 2017

Barbara S Beckman

15

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5 August 2017

Matthew E Burow

17

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5 August 2017

language of work or name

English

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publication date

9 August 2013

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5 August 2017

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5 August 2017

volume

8

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5 August 2017

issue

8

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5 August 2017

page(s)

e69291

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Creative Commons Attribution 4.0 International

5 August 2017

copyright license

start time

9 August 2013

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

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Cytokine receptor CXCR4 mediates estrogen-independent tumorigenesis, metastasis, and resistance to endocrine therapy in human breast cancer

8 July 2018

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Effects of human mesenchymal stem cells on ER-positive human breast carcinoma cells mediated through ER-SDF-1/CXCR4 crosstalk

8 July 2018

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Antiestrogenic effects of the novel sphingosine kinase-2 inhibitor ABC294640

8 July 2018

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Pharmacological Inhibition of BMK1 Suppresses Tumor Growth through Promyelocytic Leukemia Protein

8 July 2018

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Key signalling nodes in mammary gland development and cancer. Mitogen-activated protein kinase signalling in experimental models of breast cancer progression and in mammary gland development.

8 July 2018

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8 July 2018

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Design, synthesis, and biological activity of a family of novel ceramide analogues in chemoresistant breast cancer cells

8 July 2018

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Expression of Erk5 in early stage breast cancer and association with disease free survival identifies this kinase as a potential therapeutic target

8 July 2018

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Molecular effects of soy phytoalexin glyceollins in human prostate cancer cells LNCaP.

8 July 2018

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ER re-expression and re-sensitization to endocrine therapies in ER-negative breast cancers

8 July 2018

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Computational analysis of microRNA profiles and their target genes suggests significant involvement in breast cancer antiestrogen resistance

8 July 2018

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Proteomic analysis of tumor necrosis factor-alpha resistant human breast cancer cells reveals a MEK5/Erk5-mediated epithelial-mesenchymal transition phenotype

8 July 2018

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Relevance of breast cancer antiestrogen resistance genes in human breast cancer progression and tamoxifen resistance

8 July 2018

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Overexpression of TFAP2C in invasive breast cancer correlates with a poorer response to anti-hormone therapy and reduced patient survival

8 July 2018

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Reversal of the estrogen receptor negative phenotype in breast cancer and restoration of antiestrogen response.

8 July 2018

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TFAP2C controls hormone response in breast cancer cells through multiple pathways of estrogen signaling

8 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3739787

Diverse gene expression and DNA methylation profiles correlate with differential adaptation of breast cancer cells to the antiestrogens tamoxifen and fulvestrant

8 July 2018

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A collection of breast cancer cell lines for the study of functionally distinct cancer subtypes

8 July 2018

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AKT regulation of estrogen receptor beta transcriptional activity in breast cancer

8 July 2018

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Neuroprotective role of ERK1/2 and ERK5 in a dopaminergic cell line under basal conditions and in response to oxidative stress.

8 July 2018

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NF-kappaB represses E-cadherin expression and enhances epithelial to mesenchymal transition of mammary epithelial cells: potential involvement of ZEB-1 and ZEB-2.

8 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3739787

Activation of mitogen-activated protein kinase in estrogen receptor alpha-positive breast cancer cells in vitro induces an in vivo molecular phenotype of estrogen receptor alpha-negative human breast tumors

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3739787

Regulation of cellular functions by the ERK5 signalling pathway

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3739787

Evaluation of potential Stat3-regulated genes in human breast cancer

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3739787

Carcinoma invasion and metastasis: a role for epithelial-mesenchymal transition?

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3739787

Formation of an IKKalpha-dependent transcription complex is required for estrogen receptor-mediated gene activation

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3739787

The unique C-terminal tail of the mitogen-activated protein kinase ERK5 regulates its activation and nuclear shuttling.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3739787

Role of extracellular signal regulated kinase 5 in neuronal survival.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3739787

Differential Role of MEK5α and MEK5β in BMK1/ERK5 Activation

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3739787

Antiestrogen resistance in breast cancer and the role of estrogen receptor signaling.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3739787

Elevated expression levels of NCOA3, TOP1, and TFAP2C in breast tumors as predictors of poor prognosis.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3739787

MEK5 overexpression is associated with metastatic prostate cancer, and stimulates proliferation, MMP-9 expression and invasion

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3739787

Identification of mitogen-activated protein kinase kinase as a chemoresistant pathway in MCF-7 cells by using gene expression microarray

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3739787

Phosphotyrosine-specific phosphatase PTP-SL regulates the ERK5 signaling pathway

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3739787

Hyperactivation of MAPK induces loss of ERalpha expression in breast cancer cells

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3739787

Differential regulation of mitogen-activated protein kinases ERK1/2 and ERK5 by neurotrophins, neuronal activity, and cAMP in neurons.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3739787

Molecular cloning of mouse ERK5/BMK1 splice variants and characterization of ERK5 functional domains

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3739787

ERK5 and ERK2 cooperate to regulate NF-kappaB and cell transformation

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3739787

Activation of the protein kinase ERK5/BMK1 by receptor tyrosine kinases. Identification and characterization of a signaling pathway to the nucleus

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3739787

Differences in susceptibility to tumor necrosis factor alpha-induced apoptosis among MCF-7 breast cancer cell variants.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3739787

Bmk1/Erk5 is required for cell proliferation induced by epidermal growth factor

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3739787

Hyperexpression of mitogen-activated protein kinase in human breast cancer

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3739787

Identification of ERF-1 as a member of the AP2 transcription factor family

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3739787

Effect of levonorgestrel IUD and oral medroxyprogesterone acetate on glandular and stromal progesterone receptors (PRA and PRB), and estrogen receptors (ER-alpha and ER-beta) in human endometrial hyperplasia

8 July 2018

1 reference

Crossref

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0069291

Role of PELP1/MNAR signaling in ovarian tumorigenesis

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0069291

Twist regulates cytokine gene expression through a negative feedback loop that represses NF-kappaB activity

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0069291

PKC-mediated survival signaling in breast carcinoma cells: a role for MEK1-AP1 signaling

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3739787

Breast cancer progression with a Twist

26 October 2018

1 reference

12 December 2020

Immunohistochemical assay for oestrogen receptors in paraffin wax sections of breast carcinoma using a new monoclonal antibody

1 reference

12 December 2020

TNF-alpha enhances estrogen-induced cell proliferation of estrogen-dependent breast tumor cells through a complex containing nuclear factor-kappa B

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12 December 2020

AP-2 regulates the transcription of estrogen receptor (ER)-beta by acting through a methylation hotspot of the 0N promoter in prostate cancer cells

1 reference

12 December 2020

10.1371/JOURNAL.PONE.0069291

Identifiers

DOI

1 reference

5 August 2017

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5 August 2017

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