(Q34956163)

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A new challenge for successful immunotherapy by tumors that are resistant to apoptosis: two complementary signals to overcome cross-resistance

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scholarly article

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Europe PubMed Central

5 August 2017

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Europe PubMed Central

A new challenge for successful immunotherapy by tumors that are resistant to apoptosis: two complementary signals to overcome cross-resistance (English)

1 reference

Europe PubMed Central

5 August 2017

1 reference

based on heuristic

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author name string

Chuen-Pei Ng

1

1 reference

Europe PubMed Central

5 August 2017

Benjamin Bonavida

2

1 reference

Europe PubMed Central

5 August 2017

publication date

1 January 2002

1 reference

Europe PubMed Central

5 August 2017

Advances in Cancer Research

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Europe PubMed Central

5 August 2017

85

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Europe PubMed Central

5 August 2017

145-174

1 reference

Europe PubMed Central

5 August 2017

A novel anti-apoptosis gene, survivin, expressed in cancer and lymphoma

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2802%2985005-9

7 January 2021

based on heuristic

inferred from DOI database lookup

5-Fluorouracil induces apoptosis through the suppression of NF-kappaB activity in human salivary gland cancer cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2802%2985005-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Death receptors: signaling and modulation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2802%2985005-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Safety and antitumor activity of recombinant soluble Apo2 ligand

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2802%2985005-9

7 January 2021

based on heuristic

inferred from DOI database lookup

A human IAP-family gene, apollon, expressed in human brain cancer cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2802%2985005-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Activation of the STAT signaling pathway can cause expression of caspase 1 and apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2802%2985005-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Spontaneous development of plasmacytoid tumors in mice with defective Fas-Fas ligand interactions

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2802%2985005-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Adoptive immunotherapy following allogeneic bone marrow transplantation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2802%2985005-9

7 January 2021

based on heuristic

inferred from DOI database lookup

IAPs block apoptotic events induced by caspase-8 and cytochrome c by direct inhibition of distinct caspases

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2802%2985005-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Resistance to apoptosis is correlated with the reduced caspase-3 activation and enhanced expression of antiapoptotic proteins in human cervical multidrug-resistant cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2802%2985005-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Upregulation of CASP genes in human tumor cells undergoing etoposide-induced apoptosis.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2802%2985005-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2802%2985005-9

7 January 2021

based on heuristic

inferred from DOI database lookup

The lymphoproliferation mutation in Fas locally unfolds the Fas death domain

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2802%2985005-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Resistance to TRAIL-induced apoptosis in neuroblastoma cells correlates with a loss of caspase-8 expression.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2802%2985005-9

7 January 2021

based on heuristic

inferred from DOI database lookup

DIABLO promotes apoptosis by removing MIHA/XIAP from processed caspase 9

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2802%2985005-9

7 January 2021

based on heuristic

inferred from DOI database lookup

A matter of life and cell death

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2802%2985005-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Induction of CD95 ligand and apoptosis by doxorubicin is modulated by the redox state in chemosensitive- and drug-resistant tumor cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2802%2985005-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Involvement of the CD95 (APO–1/Fas) receptor/ligand system in drug–induced apoptosis in leukemia cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2802%2985005-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Immunosensitization of melanoma tumor cells to non-MHC Fas-mediated killing by MART-1-specific CTL cultures

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2802%2985005-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Immunosensitization of prostate carcinoma cell lines for lymphocytes (CTL, TIL, LAK)-mediated apoptosis via the Fas-Fas-ligand pathway of cytotoxicity

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2802%2985005-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Biochemistry of multidrug resistance mediated by the multidrug transporter

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2802%2985005-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Mitochondria and apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2802%2985005-9

7 January 2021

based on heuristic

inferred from DOI database lookup

BCL-2 family members and the mitochondria in apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2802%2985005-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Resistance to TRAIL-induced apoptosis in primitive neuroectodermal brain tumor cells correlates with a loss of caspase-8 expression.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2802%2985005-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Differential requirement for caspase 9 in apoptotic pathways in vivo.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2802%2985005-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Death cycle and Swiss army knives

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2802%2985005-9

7 January 2021

based on heuristic

inferred from DOI database lookup

The biochemistry of apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2802%2985005-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Bcl-XL protects pancreatic adenocarcinoma cells against CD95- and TRAIL-receptor-mediated apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2802%2985005-9

7 January 2021

based on heuristic

inferred from DOI database lookup

A novel family of viral death effector domain-containing molecules that inhibit both CD-95- and tumor necrosis factor receptor-1-induced apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2802%2985005-9

7 January 2021

based on heuristic

inferred from DOI database lookup

BH3-Only proteins-essential initiators of apoptotic cell death

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2802%2985005-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Resistance to CD95-mediated apoptosis through constitutive c-FLIP expression in a non-Hodgkin's lymphoma B cell line.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2802%2985005-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Inhibition of Fas-induced apoptosis by Bcl-2.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2802%2985005-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Failure of Bcl-2 to block cytochrome c redistribution during TRAIL-induced apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2802%2985005-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Cisplatin (CDDP) sensitizes human osteosarcoma cell to Fas/CD95-mediated apoptosis by down-regulating FLIP-L expression.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2802%2985005-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Modulation of apoptosis by endogenous Bcl-xL expression in MKN-45 human gastric cancer cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2802%2985005-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Reduced apoptosis and cytochrome c-mediated caspase activation in mice lacking caspase 9

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2802%2985005-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Suppression of apoptosis in mammalian cells by NAIP and a related family of IAP genes

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2802%2985005-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Cytolytic T-cell cytotoxicity is mediated through perforin and Fas lytic pathways

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2802%2985005-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Bid, a Bcl2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2802%2985005-9

7 January 2021

based on heuristic

inferred from DOI database lookup

High-dose chemotherapy: is it standard management for any common solid tumor?

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2802%2985005-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Bcl-2 Prevents CD95 (Fas/APO-1)-induced Degradation of Lamin B and Poly(ADP-ribose) Polymerase and Restores the NF-κB Signaling Pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2802%2985005-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Apoptosis as a goal of cancer therapy

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2802%2985005-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Resistance to apoptosis correlates with a highly proliferative phenotype and loss of Fas and CPP32 (caspase-3) expression in human leukemia cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2802%2985005-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Apoptosis in development

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2802%2985005-9

7 January 2021

based on heuristic

inferred from DOI database lookup

STAT-1-independent upregulation of FADD and procaspase-3 and -8 in cancer cells treated with cytotoxic drugs.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2802%2985005-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Fas ligand-independent, FADD-mediated activation of the Fas death pathway by anticancer drugs.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2802%2985005-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Enhanced sensitivity of bladder cancer cells to tumor necrosis factor related apoptosis inducing ligand mediated apoptosis by cisplatin and carboplatin

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2802%2985005-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Adoptive Immunotherapy of Established Pulmonary Metastases with LAK Cells and Recombinant Interleukin-2

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2802%2985005-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Ionizing radiation and chemotherapeutic drugs induce apoptosis in lymphocytes in the absence of Fas or FADD/MORT1 signaling. Implications for cancer therapy

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2802%2985005-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Noxa, a BH3-only member of the Bcl-2 family and candidate mediator of p53-induced apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2802%2985005-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Multidrug resistance in cancer chemotherapy

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2802%2985005-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Resistance of cultured peripheral T cells towards activation-induced cell death involves a lack of recruitment of FLICE (MACH/caspase 8) to the CD95 death-inducing signaling complex

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2802%2985005-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Mechanisms of apoptosis avoidance in cancer.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2802%2985005-9

7 January 2021

based on heuristic

inferred from DOI database lookup

A progress report on the treatment of 157 patients with advanced cancer using lymphokine-activated killer cells and interleukin-2 or high-dose interleukin-2 alone

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2802%2985005-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Fas splicing variants and their effect on apoptosis.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2802%2985005-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Hierarchy of in vitro sensitivity and resistance of tumor cells to cytotoxic effector cells, cytokines, drugs and toxins

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2802%2985005-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Two CD95 (APO-1/Fas) signaling pathways

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2802%2985005-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Transduction of Apaf-1 or caspase-9 induces apoptosis in A-172 cells that are resistant to p53-mediated apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2802%2985005-9

7 January 2021

based on heuristic

inferred from DOI database lookup

How do cytotoxic lymphocytes kill their targets?

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2802%2985005-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Cytotoxic T cells specifically induce Fas on target cells, thereby facilitating exocytosis-independent induction of apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2802%2985005-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Diversity of penetration of anti-cancer agents into solid tumours

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2802%2985005-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Inactivation of the apoptosis effector Apaf-1 in malignant melanoma

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2802%2985005-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Tumor immunology: the glass is half full

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2802%2985005-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Positive and negative regulation of apoptotic pathways by cytotoxic agents in hematological malignancies.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2802%2985005-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Immunotherapy with CTLs restricted by nonself MHC.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2802%2985005-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Novel primitive lymphoid tumours induced in transgenic mice by cooperation between myc and bcl-2.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2802%2985005-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Bcl-2 and Fas/APO-1 regulate distinct pathways to lymphocyte apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2802%2985005-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Apoptosis signaling

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2802%2985005-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Resistance to Fas-mediated apoptosis: activation of caspase 3 is regulated by cell cycle regulator p21WAF1 and IAP gene family ILP

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2802%2985005-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Multidrug resistance transporters and modulation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2802%2985005-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Downregulation of Fas ligand by shedding

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2802%2985005-9

7 January 2021

based on heuristic

inferred from DOI database lookup

CD4 T cells kill melanoma cells by mechanisms that are independent of Fas (CD95).

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2802%2985005-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Viral FLICE-inhibitory proteins (FLIPs) prevent apoptosis induced by death receptors

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2802%2985005-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Apoptosis in the pathogenesis and treatment of disease

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2802%2985005-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Targeted disruption of the mouse Caspase 8 gene ablates cell death induction by the TNF receptors, Fas/Apo1, and DR3 and is lethal prenatally.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2802%2985005-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Identification of DIABLO, a mammalian protein that promotes apoptosis by binding to and antagonizing IAP proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2802%2985005-9

7 January 2021

based on heuristic

inferred from DOI database lookup

ML-IAP, a novel inhibitor of apoptosis that is preferentially expressed in human melanomas

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2802%2985005-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Dominant-negative FADD inhibits TNFR60-, Fas/Apo1- and TRAIL-R/Apo2-mediated cell death but not gene induction

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2802%2985005-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Apoptosis-resistant mitochondria in T cells selected for resistance to Fas signaling

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2802%2985005-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Coordinated regulation of two TRAIL-R2/KILLER/DR5 mRNA isoforms by DNA damaging agents, serum and 17beta-estradiol in human breast cancer cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2802%2985005-9

7 January 2021

based on heuristic

inferred from DOI database lookup

KILLER/DR5, a novel DNA-damage inducible death receptor gene, links the p53-tumor suppressor to caspase activation and apoptotic death

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2802%2985005-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Cell death: the significance of apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2802%2985005-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Frameshift mutations in Fas, Apaf-1 and Bcl-10 in gastro-intestinal cancer of the microsatellite mutator phenotype

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2802%2985005-9

7 January 2021

based on heuristic

inferred from DOI database lookup

The IAP family: endogenous caspase inhibitors with multiple biological activities

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2802%2985005-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Requirement for Casper (c-FLIP) in regulation of death receptor-induced apoptosis and embryonic development

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2802%2985005-9

7 January 2021

based on heuristic

inferred from DOI database lookup

FADD: essential for embryo development and signaling from some, but not all, inducers of apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2802%2985005-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Fas-mediated apoptosis and activation-induced T-cell proliferation are defective in mice lacking FADD/Mort1

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2802%2985005-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Role of BAX in the apoptotic response to anticancer agents

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2802%2985005-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Actinomycin D and gemcitabine synergistically sensitize androgen-independent prostate cancer cells to Apo2L/TRAIL-mediated apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2802%2985005-9

7 January 2021

based on heuristic

inferred from DOI database lookup

An APAF-1.cytochrome c multimeric complex is a functional apoptosome that activates procaspase-9

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2802%2985005-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1016/S0065-230X(02)85005-9

1 reference

Europe PubMed Central

5 August 2017

1 reference

Europe PubMed Central

5 August 2017

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