(Q34962844)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19287398%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

title

A small molecule that directs differentiation of human ESCs into the pancreatic lineage (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19287398%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19287398%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

11

Douglas Melton

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19287398%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

2

Malgorzata Borowiak

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19287398%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

6

Lance Davidow

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19287398%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

author name string

Shuibing Chen

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19287398%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

Julia L Fox

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19287398%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

René Maehr

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19287398%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

Kenji Osafune

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19287398%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

Kelvin Lam

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19287398%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

Lee F Peng

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19287398%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

Stuart L Schreiber

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19287398%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

publication date

15 March 2009

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19287398%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

published in

Nature Chemical Biology

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19287398%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

volume

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19287398%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

issue

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19287398%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

page(s)

258-265

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19287398%20AND%20SRC:MED&resulttype=core&format=json

https://scigraph.springernature.com/pub.10.1038/nchembio.154

23 January 2020

exact match

0 references

cites work

Efficient differentiation of human embryonic stem cells to definitive endoderm

1 reference

12 December 2020

Generation of induced pluripotent stem cells without Myc from mouse and human fibroblasts

1 reference

12 December 2020

Reprogramming of human somatic cells to pluripotency with defined factors

1 reference

12 December 2020

Insulin staining of ES cell progeny from insulin uptake.

1 reference

12 December 2020

Direct interaction of all-trans-retinoic acid with protein kinase C (PKC). Implications for PKC signaling and cancer therapy

1 reference

12 December 2020

Activin B mediated induction of Pdx1 in human embryonic stem cell derived embryoid bodies

1 reference

12 December 2020

PDX-1 is required for pancreatic outgrowth and differentiation of the rostral duodenum

1 reference

12 December 2020

Differentiation of embryonic stem cells to insulin-secreting structures similar to pancreatic islets.

1 reference

12 December 2020

In vitro derivation of functional insulin-producing cells from human embryonic stem cells.

1 reference

12 December 2020

(-)-Indolactam V activates protein kinase C and induces changes in muscarinic receptor functions in SH-SY5Y human neuroblastoma cells

1 reference

12 December 2020

Differential growth regulation by all-trans retinoic acid is determined by protein kinase C alpha in human pancreatic carcinoma cells

1 reference

12 December 2020

Tissue specificity of alpha-fetoprotein messenger RNA expression during mouse embryogenesis

1 reference

12 December 2020

A role for chemistry in stem cell biology

1 reference

12 December 2020

Self-renewal of embryonic stem cells by a small molecule

1 reference

12 December 2020

Direct lineage tracing reveals the ontogeny of pancreatic cell fates during mouse embryogenesis

1 reference

12 December 2020

Production of pancreatic hormone-expressing endocrine cells from human embryonic stem cells

1 reference

12 December 2020

Fgf10 maintains notch activation, stimulates proliferation, and blocks differentiation of pancreatic epithelial cells

1 reference

12 December 2020

A glimpse into the molecular entrails of endoderm formation.

1 reference

12 December 2020

The role of the transcriptional regulator Ptf1a in converting intestinal to pancreatic progenitors

1 reference

12 December 2020

Inhibition of protein kinase C mu by various inhibitors. Differentiation from protein kinase c isoenzymes

1 reference

12 December 2020

In-vitro differentiation of pancreatic beta-cells

1 reference

12 December 2020

Retinoic acid signaling is required for a critical early step in zebrafish pancreatic development

1 reference

12 December 2020

Selective inhibition of protein kinase C isozymes by the indolocarbazole Gö 6976.

1 reference

12 December 2020

Development of definitive endoderm from embryonic stem cells in culture

1 reference

12 December 2020

Immunohistochemical localization of exocrine enzymes in normal rat pancreas

1 reference

12 December 2020

Marked differences in differentiation propensity among human embryonic stem cell lines

1 reference

12 December 2020

Induced pluripotent stem cell lines derived from human somatic cells

1 reference

12 December 2020

The Onecut transcription factor HNF-6 (OC-1) is required for timely specification of the pancreas and acts upstream of Pdx-1 in the specification cascade.

1 reference

12 December 2020

Retinoic acid binds to the C2-domain of protein kinase C(alpha).

1 reference

12 December 2020

A common pathway mediates retinoic acid and PMA-dependent programmed cell death (apoptosis) of neuronal cells

1 reference

12 December 2020

Hedgehog signaling pathway is essential for pancreas specification in the zebrafish embryo

1 reference

12 December 2020

Pancreatic endoderm derived from human embryonic stem cells generates glucose-responsive insulin-secreting cells in vivo

1 reference

12 December 2020

Fgf10 is essential for maintaining the proliferative capacity of epithelial progenitor cells during early pancreatic organogenesis

1 reference

12 December 2020

Pancreas development is promoted by cyclopamine, a hedgehog signaling inhibitor

1 reference

12 December 2020

Committing embryonic stem cells to early endocrine pancreas in vitro

1 reference

12 December 2020

Exendin 4 up-regulates expression of PDX 1 and hastens differentiation and maturation of human fetal pancreatic cells

1 reference

12 December 2020

BMP signalling regulates anteroposterior endoderm patterning in zebrafish.

1 reference

12 December 2020

Protein kinase C and other diacylglycerol effectors in cancer

1 reference

12 December 2020

Functional and morphological differentiation of fetal porcine islet-like cell clusters after transplantation into nude mice

1 reference

12 December 2020

Sonic hedgehog is required early in pancreatic islet development

1 reference

12 December 2020

Induction of pluripotent stem cells from adult human fibroblasts by defined factors

1 reference

12 December 2020

Expression of Cdx-2 in the mouse embryo and placenta: possible role in patterning of the extra-embryonic membranes

1 reference

12 December 2020

Synthetic analogues (indolactams) of (-)-indolactam-V are new congeners of the teleocidin class of tumor promoters.

1 reference

12 December 2020

Synergy between phorbol esters and retinoic acid in inducing protein kinase C activation

1 reference

12 December 2020

Activin a efficiently specifies definitive endoderm from human embryonic stem cells only when phosphatidylinositol 3-kinase signaling is suppressed.

1 reference

12 December 2020

Prospective isolation and global gene expression analysis of definitive and visceral endoderm

1 reference

12 December 2020

Insulin-promoter-factor 1 is required for pancreas development in mice

1 reference

12 December 2020

SOX9 is required for maintenance of the pancreatic progenitor cell pool

1 reference

12 December 2020