(Q34972050)

5 August 2017

title

Conformational changes in the lower palm domain of ASIC1a contribute to desensitization and RFamide modulation (English)

1 reference

5 August 2017

1 reference

Erin N Frey

1

1 reference

5 August 2017

Ryan E Pavlovicz

2

1 reference

5 August 2017

Clem John Wegman

3

1 reference

5 August 2017

Chenglong Li

4

1 reference

5 August 2017

Candice C Askwith

5

1 reference

5 August 2017

language of work or name

English

0 references

publication date

14 August 2013

1 reference

5 August 2017

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5 August 2017

volume

8

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5 August 2017

issue

8

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5 August 2017

page(s)

e71733

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Creative Commons Attribution 4.0 International

5 August 2017

copyright license

start time

14 August 2013

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

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8 July 2018

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Toxin binding reveals two open state structures for one acid-sensing ion channel

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Structure of the acid-sensing ion channel 1 in complex with the gating modifier Psalmotoxin 1

8 July 2018

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A heteromeric Texas coral snake toxin targets acid-sensing ion channels to produce pain

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Atomic level characterization of the nonproton ligand-sensing domain of ASIC3 channels.

8 July 2018

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Expressing acid-sensing ion channel 3 in the brain alters acid-evoked currents and impairs fear conditioning

8 July 2018

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Identification of a calcium permeable human acid-sensing ion channel 1 transcript variant

8 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3743763

Leu85 in the beta1-beta2 linker of ASIC1 slows activation and decreases the apparent proton affinity by stabilizing a closed conformation

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3743763

The contact region between three domains of the extracellular loop of ASIC1a is critical for channel function

8 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3743763

Dynorphin opioid peptides enhance acid-sensing ion channel 1a activity and acidosis-induced neuronal death

8 July 2018

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Pore architecture and ion sites in acid-sensing ion channels and P2X receptors

8 July 2018

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Acid sensing ion channels and acid nociception

8 July 2018

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Acid-sensing ion channel-1a in the amygdala, a novel therapeutic target in depression-related behavior

8 July 2018

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Restoring Acid-sensing ion channel-1a in the amygdala of knock-out mice rescues fear memory but not unconditioned fear responses

8 July 2018

1 reference

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Seizure termination by acidosis depends on ASIC1a

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3743763

Structure of acid-sensing ion channel 1 at 1.9 A resolution and low pH

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3743763

Targeting ASIC1a reduces innate fear and alters neuronal activity in the fear circuit.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3743763

A tarantula peptide against pain via ASIC1a channels and opioid mechanisms

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3743763

A conformation change in the extracellular domain that accompanies desensitization of acid-sensing ion channel (ASIC) 3.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3743763

Statistical potential for assessment and prediction of protein structures

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3743763

Acid-sensing ion channels: advances, questions and therapeutic opportunities.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3743763

FMRFamide-gated sodium channel and ASIC channels: a new class of ionotropic receptors for FMRFamide and related peptides.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3743763

Gating of acid-sensitive ion channel-1: release of Ca2+ block vs. allosteric mechanism

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3743763

The tarantula toxin psalmotoxin 1 inhibits acid-sensing ion channel (ASIC) 1a by increasing its apparent H+ affinity

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3743763

Neuroprotection in ischemia: blocking calcium-permeable acid-sensing ion channels.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3743763

UCSF Chimera--a visualization system for exploratory research and analysis

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3743763

A new sea anemone peptide, APETx2, inhibits ASIC3, a major acid-sensitive channel in sensory neurons

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3743763

Overexpression of acid-sensing ion channel 1a in transgenic mice increases acquired fear-related behavior

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3743763

Protons open acid-sensing ion channels by catalyzing relief of Ca2+ blockade

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3743763

Selective modulation of heteromeric ASIC proton-gated channels by neuropeptide FF.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3743763

DEG/ENaC ion channels involved in sensory transduction are modulated by cold temperature

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3743763

Modeling of loops in protein structures

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3743763

Structure and regulation of amiloride-sensitive sodium channels

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3743763

Isolation of a tarantula toxin specific for a class of proton-gated Na+ channels.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3743763

Neuropeptide FF and FMRFamide potentiate acid-evoked currents from sensory neurons and proton-gated DEG/ENaC channels

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3743763

A proton-gated cation channel involved in acid-sensing

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3743763

Comparative protein modelling by satisfaction of spatial restraints

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3743763

Reactivity of small thiolate anions and cysteine-25 in papain toward methyl methanethiosulfonate

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3743763

Black mamba venom peptides target acid-sensing ion channels to abolish pain

8 July 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0071733

Prolonged activation of ASIC1a and the time window for neuroprotection in cerebral ischaemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0071733

Acid-sensing ion channel-1 contributes to axonal degeneration in autoimmune inflammation of the central nervous system

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0071733

Alternative splicing and interaction with di- and polyvalent cations control the dynamic range of acid-sensing ion channel 1 (ASIC1).

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0071733

Strong modulation by RFamide neuropeptides of the ASIC1b/3 heteromer in competition with extracellular calcium

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0071733

Modulatory action of RFamide-related peptides on acid-sensing ionic channels is pH dependent: the role of arginine

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0071733

Endogenous arginine-phenylalanine-amide-related peptides alter steady-state desensitization of ASIC1a

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0071733

Modulation of ASIC channels in rat cerebellar Purkinje neurons by ischaemia-related signals

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0071733

PROCHECK: a program to check the stereochemical quality of protein structures

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0071733

The extracellular domain determines the kinetics of desensitization in acid-sensitive ion channel 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0071733

Asn415 in the β11-β12 Linker Decreases Proton-dependent Desensitization of ASIC1

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0071733

The interaction between two extracellular linker regions controls sustained opening of acid-sensing ion channel 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0071733

Role of FMRFamide-activated brain sodium channel in salt-sensitive hypertension.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0071733

A Nonproton Ligand Sensor in the Acid-Sensing Ion Channel

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0071733

Acid-sensing ion channel 1 is localized in brain regions with high synaptic density and contributes to fear conditioning.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3743763

DRASIC contributes to pH-gated currents in large dorsal root ganglion sensory neurons by forming heteromultimeric channels

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3743763

Acid-sensing ion channel 1 is involved in both axonal injury and demyelination in multiple sclerosis and its animal model

26 October 2018

1 reference

12 December 2020

Effects of neuropeptide SF and related peptides on acid sensing ion channel 3 and sensory neuron excitability

1 reference

12 December 2020

ASIC3 and ASIC1 mediate FMRFamide-related peptide enhancement of H+-gated currents in cultured dorsal root ganglion neurons

1 reference

12 December 2020

Chemical modification of the RTEM-1 thiol beta-lactamase by thiol-selective reagents: evidence for activation of the primary nucleophile of the beta-lactamase active site by adjacent functional groups

1 reference

12 December 2020

Mice lacking acid-sensing ion channels (ASIC) 1 or 2, but not ASIC3, show increased pain behaviour in the formalin test

1 reference

12 December 2020

10.1371/JOURNAL.PONE.0071733

Identifiers

DOI

1 reference

5 August 2017

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5 August 2017

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