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Emerging roles for crk in human cancer
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scholarly article
1 reference
stated in
Europe PubMed Central
PubMed ID
21779437
retrieved
5 August 2017
title
Emerging roles for crk in human cancer
(English)
1 reference
stated in
Europe PubMed Central
PubMed ID
21779437
retrieved
5 August 2017
author name string
Ganapathy Sriram
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed ID
21779437
retrieved
5 August 2017
Raymond B Birge
series ordinal
2
1 reference
stated in
Europe PubMed Central
PubMed ID
21779437
retrieved
5 August 2017
publication date
1 November 2010
1 reference
stated in
Europe PubMed Central
PubMed ID
21779437
retrieved
5 August 2017
published in
Genes & Cancer
1 reference
stated in
Europe PubMed Central
PubMed ID
21779437
retrieved
5 August 2017
volume
1
1 reference
stated in
Europe PubMed Central
PubMed ID
21779437
retrieved
5 August 2017
issue
11
1 reference
stated in
Europe PubMed Central
PubMed ID
21779437
retrieved
5 August 2017
page(s)
1132-1139
1 reference
stated in
Europe PubMed Central
PubMed ID
21779437
retrieved
5 August 2017
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Proteins that bind the Src homology 3 domain of CrkI have distinct roles in Crk transformation
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SH2 Domains Recognize Contextual Peptide Sequence Information to Determine Selectivity
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PubMed Central
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8 July 2018
miR-126 functions as a tumour suppressor in human gastric cancer
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8 July 2018
The role of Crk/Dock180/Rac1 pathway in the malignant behavior of human ovarian cancer cell SKOV3.
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8 July 2018
CrkII transgene induces atypical mammary gland development and tumorigenesis
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8 July 2018
Genomic and functional analysis identifies CRKL as an oncogene amplified in lung cancer
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3092275
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8 July 2018
A BCR-ABL mutant lacking direct binding sites for the GRB2, CBL and CRKL adapter proteins fails to induce leukemia in mice
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PubMed Central
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8 July 2018
Regulation of miRNA expression by Src and contact normalization: effects on nonanchored cell growth and migration.
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8 July 2018
Cancer statistics, 2009
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3092275
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8 July 2018
Crk and CrkL adaptor proteins: networks for physiological and pathological signaling
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8 July 2018
Highly parallel identification of essential genes in cancer cells
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High-performance liquid chromatography/nano-electrospray ionization tandem mass spectrometry, two-dimensional difference in-gel electrophoresis and gene microarray identification of lymphatic metastasis-associated biomarkers.
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8 July 2018
MicroRNA-126 inhibits invasion in non-small cell lung carcinoma cell lines
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3092275
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8 July 2018
SRC family nonreceptor tyrosine kinases as molecular targets for cancer therapy
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3092275
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8 July 2018
Signaling adaptor protein Crk is indispensable for malignant feature of glioblastoma cell line KMG4.
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3092275
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8 July 2018
Aggressive breast cancer cells are dependent on activated Abl kinases for proliferation, anchorage-independent growth and survival
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3092275
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8 July 2018
The 2007 WHO classification of tumours of the central nervous system
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3092275
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8 July 2018
Structural basis for the transforming activity of human cancer-related signaling adaptor protein CRK
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3092275
retrieved
8 July 2018
Proline cis-trans isomerization controls autoinhibition of a signaling protein
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3092275
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8 July 2018
Cardiovascular and craniofacial defects in Crk-null mice
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3092275
retrieved
8 July 2018
The EphB4 receptor suppresses breast cancer cell tumorigenicity through an Abl-Crk pathway
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3092275
retrieved
8 July 2018
Solution structure and folding characteristics of the C-terminal SH3 domain of c-Crk-II.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3092275
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8 July 2018
Activation of Abl tyrosine kinases promotes invasion of aggressive breast cancer cells
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3092275
retrieved
8 July 2018
Involvement of adaptor protein Crk in malignant feature of human ovarian cancer cell line MCAS.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3092275
retrieved
8 July 2018
Transactivation of Abl by the Crk II adapter protein requires a PNAY sequence in the Crk C-terminal SH3 domain
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3092275
retrieved
8 July 2018
CrkIII: a novel and biologically distinct member of the Crk family of adaptor proteins
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3092275
retrieved
8 July 2018
Crk adapter proteins promote an epithelial-mesenchymal-like transition and are required for HGF-mediated cell spreading and breakdown of epithelial adherens junctions
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3092275
retrieved
8 July 2018
Molecular and immunohistochemical analysis of signaling adaptor protein Crk in human cancers
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3092275
retrieved
8 July 2018
Crk family adaptors-signalling complex formation and biological roles
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3092275
retrieved
8 July 2018
Crk family adaptor proteins trans-activate c-Abl kinase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3092275
retrieved
8 July 2018
Mice lacking the homologue of the human 22q11.2 gene CRKL phenocopy neurocristopathies of DiGeorge syndrome
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3092275
retrieved
8 July 2018
Structural requirements for function of the Crkl adapter protein in fibroblasts and hematopoietic cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3092275
retrieved
8 July 2018
Phosphorylation of CrkII adaptor protein at tyrosine 221 by epidermal growth factor receptor
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3092275
retrieved
8 July 2018
CAS/Crk coupling serves as a "molecular switch" for induction of cell migration
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3092275
retrieved
8 July 2018
Epithelial differentiation and the control of metastasis in carcinomas
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3092275
retrieved
8 July 2018
Direct binding of CRKL to BCR-ABL is not required for BCR-ABL transformation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3092275
retrieved
8 July 2018
The CRKL adaptor protein transforms fibroblasts and functions in transformation by the BCR-ABL oncogene
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3092275
retrieved
8 July 2018
Specific interactions outside the proline-rich core of two classes of Src homology 3 ligands
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3092275
retrieved
8 July 2018
The Met receptor tyrosine kinase transduces motility, proliferation, and morphogenic signals of scatter factor/hepatocyte growth factor in epithelial cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3092275
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8 July 2018
Isolation and chromosomal localization of CRKL, a human crk-like gene
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3092275
retrieved
8 July 2018
c-Abl kinase regulates the protein binding activity of c-Crk
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3092275
retrieved
8 July 2018
Crkl is the major tyrosine-phosphorylated protein in neutrophils from patients with chronic myelogenous leukemia
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3092275
retrieved
8 July 2018
Abl protein-tyrosine kinase selects the Crk adapter as a substrate using SH3-binding sites
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3092275
retrieved
8 July 2018
Four proline-rich sequences of the guanine-nucleotide exchange factor C3G bind with unique specificity to the first Src homology 3 domain of Crk
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3092275
retrieved
8 July 2018
Direct demonstration of an intramolecular SH2-phosphotyrosine interaction in the Crk protein
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3092275
retrieved
8 July 2018
Identification and characterization of a high-affinity interaction between v-Crk and tyrosine-phosphorylated paxillin in CT10-transformed fibroblasts
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3092275
retrieved
8 July 2018
SH2 domains recognize specific phosphopeptide sequences
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3092275
retrieved
8 July 2018
C3G, a guanine nucleotide-releasing protein expressed ubiquitously, binds to the Src homology 3 domains of CRK and GRB2/ASH proteins
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3092275
retrieved
8 July 2018
CRKL links p210BCR/ABL with paxillin in chronic myelogenous leukemia cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3092275
retrieved
8 July 2018
Phage display selection of ligand residues important for Src homology 3 domain binding specificity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3092275
retrieved
8 July 2018
Cell transformation by pp60c-src mutated in the carboxy-terminal regulatory domain
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3092275
retrieved
8 July 2018
A novel viral oncogene with structural similarity to phospholipase C
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3092275
retrieved
8 July 2018
Cell transformation by the viral src oncogene
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3092275
retrieved
8 July 2018
Identification of domains of the v-crk oncogene product sufficient for association with phosphotyrosine-containing proteins
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3092275
retrieved
8 July 2018
Binding of Transforming Protein, P47 gag-crk , to a Broad Range of Phosphotyrosine-containing Proteins
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3092275
retrieved
8 July 2018
Two species of human CRK cDNA encode proteins with distinct biological activities
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3092275
retrieved
8 July 2018
The product of the cellular crk gene consists primarily of SH2 and SH3 regions
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3092275
retrieved
8 July 2018
Adaptor protein Crk induces Src-dependent activation of p38 MAPK in regulation of synovial sarcoma cell proliferation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3092275
retrieved
26 October 2018
Adaptor molecule Crk is required for sustained phosphorylation of Grb2-associated binder 1 and hepatocyte growth factor-induced cell motility of human synovial sarcoma cell lines
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3092275
retrieved
26 October 2018
CrkI and CrkII function as key signaling integrators for migration and invasion of cancer cells.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3092275
retrieved
26 October 2018
Increased C-CRK proto-oncogene expression is associated with an aggressive phenotype in lung adenocarcinomas
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3092275
retrieved
26 October 2018
Cytoplasmic c-Abl provides a molecular 'Rheostat' controlling carcinoma cell survival and invasion
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3092275
retrieved
26 October 2018
CrkI adapter protein modulates cell migration and invasion in glioblastoma
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3092275
retrieved
26 October 2018
BCR/ABL P190 transgenic mice develop leukemia in the absence of Crkl
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3092275
retrieved
26 October 2018
Eph tumour suppression: the dark side of Gleevec
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/21779437
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1177/1947601910397188
1 reference
stated in
Europe PubMed Central
PubMed ID
21779437
retrieved
5 August 2017
PMCID
3092275
1 reference
stated in
Europe PubMed Central
PubMed ID
21779437
retrieved
5 August 2017
PubMed ID
21779437
1 reference
stated in
Europe PubMed Central
PubMed ID
21779437
retrieved
5 August 2017
ResearchGate publication ID
51511869
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