(Q44040285)

29 November 2017

BCR/ABL P190 transgenic mice develop leukemia in the absence of Crkl (English)

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29 November 2017

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1

Bianca Hemmeryckx

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author name string

Anja Reichert

2

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29 November 2017

Meguru Watanabe

3

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29 November 2017

Vesa Kaartinen

4

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29 November 2017

Ron de Jong

5

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29 November 2017

Paul K Pattengale

6

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29 November 2017

John Groffen

7

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29 November 2017

Nora Heisterkamp

8

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29 November 2017

language of work or name

English

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publication date

1 May 2002

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29 November 2017

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29 November 2017

21

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29 November 2017

3225-3231

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29 November 2017

20

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https://scigraph.springernature.com/pub.10.1038/sj.onc.1205452

29 November 2017

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cites work

Tyrosine 207 in CRKL is the BCR/ABL phosphorylation site

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205452

p62(dok), a negative regulator of Ras and mitogen-activated protein kinase (MAPK) activity, opposes leukemogenesis by p210(bcr-abl)

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205452

Physiological signals and oncogenesis mediated through Crk family adapter proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205452

Crk family adaptors-signalling complex formation and biological roles

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205452

Clinical resistance to STI-571 cancer therapy caused by BCR-ABL gene mutation or amplification

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205452

Mice lacking the homologue of the human 22q11.2 gene CRKL phenocopy neurocristopathies of DiGeorge syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205452

Acute leukaemia in bcr/abl transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205452

Abnormal lung development and cleft palate in mice lacking TGF-beta 3 indicates defects of epithelial-mesenchymal interaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205452

Chronic myelogenous leukemia blast cell proliferation is inhibited by peptides that disrupt Grb2-SoS complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205452

Cell-penetrating SH3 domain blocker peptides inhibit proliferation of primary blast cells from CML patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205452

CRKL binding to BCR-ABL and BCR-ABL transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205452

Tyrosine phosphorylation of Grb2 by Bcr/Abl and epidermal growth factor receptor: a novel regulatory mechanism for tyrosine kinase signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205452

Interleukin 3 and granulocyte-macrophage colony-stimulating factor are not required for induction of chronic myeloid leukemia-like myeloproliferative disease in mice by BCR/ABL.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205452

Two species of human CRK cDNA encode proteins with distinct biological activities

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205452

Role of the adapter protein CRKL in signal transduction of normal hematopoietic and BCR/ABL-transformed cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205452

21 January 2018

Chronic myeloid leukemia

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1205452

The CRKL adaptor protein transforms fibroblasts and functions in transformation by the BCR-ABL oncogene

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205452

Inhibition of Grb2 and Crkl proteins results in growth inhibition of Philadelphia chromosome positive leukemic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205452

The BCR/ABL oncogene alters interaction of the adapter proteins CRKL and CRK with cellular proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205452

Increased neutrophil respiratory burst in bcr-null mutants

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205452

Bcr/Abl associated leukemogenesis in bcr null mutant mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205452

The leukaemic oncoproteins Bcr-Abl and Tel-Abl (ETV6/Abl) have altered substrate preferences and activate similar intracellular signalling pathways.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205452

21 January 2018

Identifiers

DOI

10.1038/SJ.ONC.1205452

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29 November 2017

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