(Q34975110)

5 August 2017

Integration of population pharmacokinetics and pharmacogenetics: an aid to optimal nevirapine dose selection in HIV-infected individuals (English)

1 reference

5 August 2017

1 reference

1 reference

11

Jürgen Rockstroh

1 reference

5 August 2017

9

Gerd Fätkenheuer

1 reference

5 August 2017

Marco Siccardi

6

0 references

Andrew Owen

object named as

Andrew Owen

14

0 references

Heidy Hendra

object named as

Heidy Hendra

4

1 reference

ORCID Public Data File 2021

author name string

Alessandro Schipani

1

1 reference

5 August 2017

Christoph Wyen

2

1 reference

5 August 2017

Tabitha Mahungu

3

1 reference

5 August 2017

Deirdre Egan

5

1 reference

5 August 2017

Gerry Davies

7

1 reference

5 August 2017

Saye Khoo

8

1 reference

5 August 2017

Michael Youle

10

1 reference

5 August 2017

Norbert H Brockmeyer

12

1 reference

5 August 2017

Margaret A Johnson

13

1 reference

5 August 2017

David J Back

15

1 reference

5 August 2017

German Competence Network for HIV/AIDS

16

1 reference

5 August 2017

language of work or name

English

0 references

publication date

25 March 2011

1 reference

Journal of Antimicrobial Chemotherapy

5 August 2017

1 reference

5 August 2017

66

1 reference

5 August 2017

6

1 reference

5 August 2017

1332-1339

1 reference

Population pharmacokinetic-pharmacogenetic study of nevirapine in HIV-infected Cambodian patients

5 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3092713

Crystal structure of a cytochrome P450 2B6 genetic variant in complex with the inhibitor 4-(4-chlorophenyl)imidazole at 2.0-A resolution

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3092713

CYP2B6 (c.516G→T) and CYP2A6 (*9B and/or *17) polymorphisms are independent predictors of efavirenz plasma concentrations in HIV-infected patients

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3092713

Associations between CYP2B6 polymorphisms and pharmacokinetics after a single dose of nevirapine or efavirenz in African americans

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3092713

CYP2B6: new insights into a historically overlooked cytochrome P450 isozyme

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3092713

Impact of CYP2B6 983T>C polymorphism on non-nucleoside reverse transcriptase inhibitor plasma concentrations in HIV-infected patients

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3092713

Polymorphic CYP2B6: molecular mechanisms and emerging clinical significance

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3092713

Cytochrome P450 2B6 (CYP2B6) G516T influences nevirapine plasma concentrations in HIV-infected patients in Uganda

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3092713

Once-daily nevirapine dosing: a pharmacokinetics, efficacy and safety review

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3092713

Prevalence of CYP2B6 alleles in malaria-endemic populations of West Africa and Papua New Guinea

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3092713

Perl-speaks-NONMEM (PsN)--a Perl module for NONMEM related programming

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3092713

Drug-induced liver injury associated with the use of nonnucleoside reverse-transcriptase inhibitors

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3092713

HIV resistance to nevirapine and other non-nucleoside reverse transcriptase inhibitors

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3092713

Constitutive androstane receptor and pregnane X receptor gene expression in human liver: interindividual variability and correlation with CYP2B6 mRNA levels

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3092713

Population pharmacokinetics of nevirapine in an unselected cohort of HIV-1-infected individuals

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3092713

The steady-state pharmacokinetics of nevirapine during once daily and twice daily dosing in HIV-1-infected individuals

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3092713

Intrapartum and neonatal single-dose nevirapine compared with zidovudine for prevention of mother-to-child transmission of HIV-1 in Kampala, Uganda: HIVNET 012 randomised trial

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3092713

A comprehensive hepatic safety analysis of nevirapine in different populations of HIV infected patients

8 July 2018

1 reference

https://api.crossref.org/works/10.1093%2FJAC%2FDKR087

Influence of CYP2B6 polymorphism on plasma and intracellular concentrations and toxicity of efavirenz and nevirapine in HIV-infected patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJAC%2FDKR087

Cytochrome P450 2B6 516G-->T is associated with plasma concentrations of nevirapine at both 200 mg twice daily and 400 mg once daily in an ethnically diverse population

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJAC%2FDKR087

High exposure to nevirapine in plasma is associated with an improved virological response in HIV-1-infected individuals

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJAC%2FDKR087

Low nevirapine plasma concentrations predict virological failure in an unselected HIV-1-infected population

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJAC%2FDKR087

Intracellular and plasma pharmacokinetics of nevirapine in human immunodeficiency virus-infected individuals

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJAC%2FDKR087

Pharmacogenetics-based population pharmacokinetic analysis of efavirenz in HIV-1-infected individuals

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJAC%2FDKR087

Once- or twice-daily dosing of nevirapine in HIV-infected adults: a population pharmacokinetics approach

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJAC%2FDKR087

Genetic variability of CYP2B6 in populations of African and Asian origin: allele frequencies, novel functional variants, and possible implications for anti-HIV therapy with efavirenz

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJAC%2FDKR087

Pharmacokinetics of nevirapine: once-daily versus twice-daily dosing in the 2NN study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJAC%2FDKR087

Human cytochrome P4502B6: interindividual hepatic expression, substrate specificity, and role in procarcinogen activation

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3092713

Characterization of the in vitro biotransformation of the HIV-1 reverse transcriptase inhibitor nevirapine by human hepatic cytochromes P-450

9 December 2018

1 reference

12 December 2020

European guidelines for the clinical management and treatment of HIV-infected adults in Europe

1 reference

12 December 2020

Effect of misspecification of the absorption process on subsequent parameter estimation in population analysis

1 reference

12 December 2020

Pharmacogenetics of nevirapine-associated hepatotoxicity: an Adult AIDS Clinical Trials Group collaboration

1 reference

12 December 2020

Identifiers

DOI

10.1093/JAC/DKR087

1 reference

5 August 2017

1 reference

5 August 2017

1 reference