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The amyloid formation mechanism in human IAPP: dimers have β-strand monomer-monomer interfaces
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Europe PubMed Central
PMCID
3093713
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21517093%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 January 2020
title
The amyloid formation mechanism in human IAPP: dimers have β-strand monomer-monomer interfaces
(English)
1 reference
stated in
Europe PubMed Central
PMCID
3093713
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21517093%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 January 2020
author
Chun Wu
series ordinal
2
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Europe PubMed Central
PMCID
3093713
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21517093%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 January 2020
Joan-Emma Shea
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3
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Joan-Emma Shea
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Europe PubMed Central
PMCID
3093713
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21517093%20AND%20SRC:MED&resulttype=core&format=json
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29 January 2020
author name string
Nicholas F Dupuis
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1
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Europe PubMed Central
PMCID
3093713
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21517093%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 January 2020
Michael T Bowers
series ordinal
4
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3093713
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21517093%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 January 2020
language of work or name
English
0 references
publication date
25 April 2011
1 reference
stated in
Europe PubMed Central
PMCID
3093713
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21517093%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 January 2020
published in
Journal of the American Chemical Society
1 reference
stated in
Europe PubMed Central
PMCID
3093713
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21517093%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 January 2020
volume
133
1 reference
stated in
Europe PubMed Central
PMCID
3093713
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21517093%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 January 2020
page(s)
7240-7243
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Europe PubMed Central
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3093713
reference URL
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retrieved
29 January 2020
issue
19
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stated in
Europe PubMed Central
PMCID
3093713
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21517093%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 January 2020
cites work
Ion mobility-mass spectrometry reveals a conformational conversion from random assembly to β-sheet in amyloid fibril formation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3093713
retrieved
8 July 2018
On the origins of the weak folding cooperativity of a designed ββα ultrafast protein FSD-1.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3093713
retrieved
8 July 2018
Stable and metastable states of human amylin in solution.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3093713
retrieved
8 July 2018
Amyloid-β protein oligomerization and the importance of tetramers and dodecamers in the aetiology of Alzheimer's disease
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3093713
retrieved
8 July 2018
Unfolded-state dynamics and structure of protein L characterized by simulation and experiment
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3093713
retrieved
8 July 2018
Solution structures of rat amylin peptide: simulation, theory, and experiment
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3093713
retrieved
8 July 2018
Principles governing oligomer formation in amyloidogenic peptides
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3093713
retrieved
8 July 2018
Molecular simulation of ab initio protein folding for a millisecond folder NTL9(1-39)
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3093713
retrieved
8 July 2018
Human islet amyloid polypeptide monomers form ordered beta-hairpins: a possible direct amyloidogenic precursor
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3093713
retrieved
8 July 2018
Sequence and crowding effects in the aggregation of a 10-residue fragment derived from islet amyloid polypeptide
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3093713
retrieved
8 July 2018
Atomic structures of IAPP (amylin) fusions suggest a mechanism for fibrillation and the role of insulin in the process
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3093713
retrieved
8 July 2018
A role for helical intermediates in amyloid formation by natively unfolded polypeptides?
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3093713
retrieved
8 July 2018
Spermine binding to Parkinson's protein alpha-synuclein and its disease-related A30P and A53T mutants
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3093713
retrieved
8 July 2018
Atomic structure of the cross-β spine of islet amyloid polypeptide (amylin)
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3093713
retrieved
8 July 2018
A test on peptide stability of AMBER force fields with implicit solvation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3093713
retrieved
8 July 2018
Peptide conformation and supramolecular organization in amylin fibrils: constraints from solid-state NMR.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3093713
retrieved
8 July 2018
Toxic human islet amyloid polypeptide (h-IAPP) oligomers are intracellular, and vaccination to induce anti-toxic oligomer antibodies does not prevent h-IAPP-induced beta-cell apoptosis in h-IAPP transgenic mice
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3093713
retrieved
8 July 2018
Direct detection of transient alpha-helical states in islet amyloid polypeptide
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3093713
retrieved
8 July 2018
Protein misfolding, functional amyloid, and human disease
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3093713
retrieved
8 July 2018
Design of a mimic of nonamyloidogenic and bioactive human islet amyloid polypeptide (IAPP) as nanomolar affinity inhibitor of IAPP cytotoxic fibrillogenesis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3093713
retrieved
8 July 2018
Amyloid fibrils in human insulinoma and islets of Langerhans of the diabetic cat are derived from a neuropeptide-like protein also present in normal islet cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3093713
retrieved
8 July 2018
Identification of hot regions of the Abeta-IAPP interaction interface as high-affinity binding sites in both cross- and self-association
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3093713
retrieved
26 October 2018
Recovery and purification of highly aggregation-prone disulfide-containing peptides: application to islet amyloid polypeptide
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3093713
retrieved
26 October 2018
Structure-based design and study of non-amyloidogenic, double N-methylated IAPP amyloid core sequences as inhibitors of IAPP amyloid formation and cytotoxicity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3093713
retrieved
26 October 2018
Amyloid Fibril Formation from Full-Length and Fragments of Amylin
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/21517093
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Conformational transitions of islet amyloid polypeptide (IAPP) in amyloid formation in vitro
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/21517093
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Inhibition of hIAPP amyloid-fibril formation and apoptotic cell death by a designed hIAPP amyloid- core-containing hexapeptide
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/21517093
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1021/JA1081537
1 reference
stated in
Europe PubMed Central
PMCID
3093713
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21517093%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 January 2020
PMCID
3093713
1 reference
stated in
Europe PubMed Central
PMCID
3093713
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21517093%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 January 2020
PubMed ID
21517093
1 reference
stated in
Europe PubMed Central
PMCID
3093713
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21517093%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 January 2020
ResearchGate publication ID
51074093
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