(Q34980209)

5 August 2017

1 reference

31 January 2021

Efficacy of alpha1-antitrypsin augmentation therapy in conditions other than pulmonary emphysema (English)

1 reference

hypersensitivity vasculitis

5 August 2017

1 reference

13 December 2019

1 reference

13 December 2019

1 reference

alpha-1-antitrypsin deficiency

31 January 2021

1 reference

31 January 2021

Serpin family A member 1

1 reference

31 January 2021

1 reference

Ignacio Blanco

1

1 reference

5 August 2017

Beatriz Lara

series ordinal

2

1 reference

5 August 2017

Frederick de Serres

series ordinal

3

1 reference

5 August 2017

12 April 2011

10 references

Orphanet Journal of Rare Diseases

5 August 2017

13 March 2019

22 March 2019

24 March 2019

22 April 2019

17 June 2019

20 November 2019

27 November 2019

13 December 2019

31 January 2021

10 references

5 August 2017

13 March 2019

22 March 2019

24 March 2019

22 April 2019

17 June 2019

20 November 2019

27 November 2019

13 December 2019

31 January 2021

6

1 reference

5 August 2017

14

1 reference

Creative Commons Attribution 2.0 Generic

5 August 2017

9 references

13 March 2019

22 March 2019

24 March 2019

22 April 2019

17 June 2019

20 November 2019

27 November 2019

13 December 2019

on focus list of Wikimedia project

31 January 2021

copyright status

copyrighted

0 references

ScienceSource

0 references

exact match

https://scigraph.springernature.com/pub.10.1186/1750-1172-6-14

0 references

cites work

α 1-antitrypsin enhances insulin secretion and prevents cytokine-mediated apoptosis in pancreatic β-cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3094201

Therapeutic efficacy of α-1 antitrypsin augmentation therapy on the loss of lung tissue: an integrated analysis of 2 randomised clinical trials using computed tomography densitometry

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3094201

Alpha₁-antitrypsin deficiency-related alleles Z and S and the risk of Wegener's granulomatosis

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3094201

Augmentation therapy in alpha-1 antitrypsin deficiency: advances and controversies

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3094201

Intravenous alpha-1 antitrypsin augmentation therapy for treating patients with alpha-1 antitrypsin deficiency and lung disease

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3094201

Long-term augmentation therapy with alpha-1 antitrypsin in an MZ-AAT severe persistent asthma

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3094201

New Findings in PiZZ alpha1-antitrypsin deficiency-related panniculitis. Demonstration of skin polymers and high dosing requirements of intravenous augmentation therapy

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3094201

Alpha(1)-antitrypsin inhibits epithelial Na+ transport in vitro and in vivo

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3094201

PI S and PI Z alpha-1 antitrypsin deficiency worldwide. A review of existing genetic epidemiological data

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3094201

Inhibition profiles of human tissue kallikreins by serine protease inhibitors

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3094201

A novel antiapoptotic role for alpha1-antitrypsin in the prevention of pulmonary emphysema

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3094201

Estimated numbers and prevalence of PI*S and PI*Z alleles of alpha1-antitrypsin deficiency in European countries.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3094201

Alpha1-antitrypsin deficiency

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3094201

Granzyme M is a regulatory protease that inactivates proteinase inhibitor 9, an endogenous inhibitor of granzyme B

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3094201

Alpha 1-antitrypsin binds to and interferes with functionality of EspB from atypical and typical enteropathogenic Escherichia coli strains

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3094201

Human neutrophil-derived elastase induces airway smooth muscle cell proliferation

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3094201

Inhibition of tryptase release from human colon mast cells by protease inhibitors.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3094201

Recombinant alpha 1-proteinase inhibitor blocks antigen- and mediator-induced airway responses in sheep

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3094201

Alpha-1-antitrypsin inhibits human immunodeficiency virus type 1.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3094201

A randomized clinical trial of alpha(1)-antitrypsin augmentation therapy

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3094201

Kinetic mechanism of the inhibition of cathepsin G by alpha 1-antichymotrypsin and alpha 1-proteinase inhibitor.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3094201

Does alpha1-antitrypsin augmentation therapy slow the annual decline in FEV1 in patients with severe hereditary alpha1-antitrypsin deficiency? Wissenschaftliche Arbeitsgemeinschaft zur Therapie von Lungenerkrankungen (WATL) alpha1-AT study group.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3094201

alpha 1-antitrypsin deficiency-associated panniculitis: resolution with intravenous alpha 1-antitrypsin administration and liver transplantation

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3094201

The serpin superfamily of proteinase inhibitors: structure, function, and regulation

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3094201

Replacement therapy of alpha 1-antitrypsin deficiency. Reversal of protease-antiprotease imbalance within the alveolar structures of PiZ subjects

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3094201

Kinetics of association of serine proteinases with native and oxidized alpha-1-proteinase inhibitor and alpha-1-antichymotrypsin.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3094201

Human plasma proteinase inhibitors

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3094201

Proteolysis by neutrophils. Relative importance of cell-substrate contact and oxidative inactivation of proteinase inhibitors in vitro

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3094201

Replacement therapy for alpha 1-antitrypsin deficiency associated with emphysema

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3094201

Panniculitis associated with severe alpha 1-antitrypsin deficiency. Treatment and review of the literature

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3094201

Prevention of tissue damage: inhibition of myeloperoxidase mediated inactivation of alpha 1-proteinase inhibitor by N-acetyl cysteine, glutathione, and methionine

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3094201

Characterization of proteinase-3 (PR-3), a neutrophil serine proteinase. Structural and functional properties

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3094201

Alpha,-antitrypsin and leukocyte elastase in infected and noninfected sputum

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3094201

Serum Inhibitors of Fibrinolysis

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3094201

American Thoracic Society/European Respiratory Society statement: standards for the diagnosis and management of individuals with alpha-1 antitrypsin deficiency.

8 July 2018

1 reference

https://api.crossref.org/works/10.1186%2F1750-1172-6-14

Inhibition of proteinase 3 by [alpha]1-antitrypsin in vitro predicts very fast inhibition in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1750-1172-6-14

Mutants of plasminogen activator inhibitor-1 designed to inhibit neutrophil elastase and cathepsin G are more effective in vivo than their endogenous inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1750-1172-6-14

Role of human neutrophil peptides in lung inflammation associated with α1-antitrypsin deficiency

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1750-1172-6-14

Alpha1-antitrypsin inhibits the activity of the matriptase catalytic domain in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1750-1172-6-14

Exploring the role of CT densitometry: a randomised study of augmentation therapy in alpha1-antitrypsin deficiency.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1750-1172-6-14

Alpha1-antitrypsin inhibits Moraxella catarrhalis MID protein-induced tonsillar B cell proliferation and IL-6 release

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1750-1172-6-14

Alpha-1-antitrypsin deficiency associated with panniculitis treated with plasma exchange therapy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1750-1172-6-14

Abnormal overexpression of mastocytes in skin biopsies of fibromyalgia patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1750-1172-6-14

Neutrophil Proteases Activate Eosinophil Function in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1750-1172-6-14

Inhibition of neutrophil elastase by alpha1-protease inhibitor at the surface of human polymorphonuclear neutrophils

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3094201

Inhibition of tryptase and chymase induced nucleated cell infiltration by proteinase inhibitors.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3094201

Alpha1-antitrypsin replacement therapy controls fibromyalgia symptoms in 2 patients with PI ZZ alpha1-antitrypsin deficiency.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3094201

Inhibition of histamine release from human mast cells by natural chymase inhibitors.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3094201

Increased levels of elastase and alpha1-antitrypsin in sputum of asthmatic patients.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3094201

Sheep mast cell proteinase-1, a serine proteinase with both tryptase- and chymase-like properties, is inhibited by plasma proteinase inhibitors and is mitogenic for bovine pulmonary artery fibroblasts

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3094201

Human kallikrein 4: enzymatic activity, inhibition, and degradation of extracellular matrix proteins

26 October 2018

1 reference

https://api.crossref.org/works/10.1186%2F1750-1172-6-14

Severe panniculitis caused by homozygous ZZ alpha1-antitrypsin deficiency treated successfully with human purified enzyme (Prolastin)

21 January 2018

1 reference

12 December 2020

Inhibition of human granulocyte elastase by serum alpha-1-antitrypsin

1 reference

12 December 2020

Antagonistic effect of human alpha-1-antitrypsin on excystation of Cryptosporidium parvum oocysts

1 reference

12 December 2020

Survival and FEV1 decline in individuals with severe deficiency of alpha1-antitrypsin. The Alpha-1-Antitrypsin Deficiency Registry Study Group

1 reference

12 December 2020

Aerosolized prolastin suppresses bacterial proliferation in a model of chronic Pseudomonas aeruginosa lung infection

1 reference

12 December 2020

Inhibition of leukocytic elastase from purulent sputum by alpha 1 -antitrypsin

1 reference

12 December 2020

The interaction of alpha-1-antitrypsin with chymotrypsin, trypsin and elastase

1 reference

12 December 2020

Serm alpha-antitrypsin types: elastase inhibition versus trypsin inhibition

1 reference

12 December 2020

Low plasma levels of monocyte chemoattractant protein-1 (MCP-1), tumor necrosis factor-alpha (TNFalpha), and vascular endothelial growth factor (VEGF) in patients with alpha1-antitrypsin deficiency-related fibromyalgia

1 reference

12 December 2020

Functional protection by acute phase proteins alpha(1)-acid glycoprotein and alpha(1)-antitrypsin against ischemia/reperfusion injury by preventing apoptosis and inflammation

1 reference

12 December 2020

Longitudinal follow-up of patients with alpha(1)-protease inhibitor deficiency before and during therapy with IV alpha(1)-protease inhibitor

1 reference

12 December 2020

Inhibition of urokinase by complex formation with human alpha1-antitrypsin

1 reference

12 December 2020

Inhibition of Entamoeba Histolytica Cytotoxin by Alpha 1 Antiprotease and Alpha 2 Macroglobulin *

1 reference

12 December 2020

Necrotic panniculitis with alpha-1 antitrypsin deficiency

1 reference

12 December 2020

Reactivity of alpha 1-antitrypsin mutants against proteolytic enzymes of the kallikrein-kinin, complement, and fibrinolytic systems

1 reference

12 December 2020

Analysis of the plasma elimination kinetics and conformational stabilities of native, proteinase-complexed, and reactive site cleaved serpins: comparison of alpha 1-proteinase inhibitor, alpha 1-antichymotrypsin, antithrombin III, alpha 2-antiplasmi

1 reference

12 December 2020

Current status of alpha-1-antitrypsin replacement therapy: recommendations for the management of patients with severe hereditary deficiency. Ad Hoc Committee on Alpha-1-Antitrypsin Replacement Therapy of the Standards Committee, Canadian Thoracic So

1 reference

12 December 2020

Effective treatment with alpha 1-protease inhibitor of chronic cutaneous vasculitis associated with alpha 1-antitrypsin deficiency

1 reference

12 December 2020

The interaction of alpha 1-proteinase inhibitor and tissue kallikrein in controlling allergic ovine airway hyperresponsiveness

1 reference

12 December 2020

Treatment of alpha-1-antitrypsin deficiency, massive edema, and panniculitis with alpha-1 protease inhibitor

1 reference

12 December 2020

Cytotoxic concentrations of alpha-defensins in the lungs of individuals with alpha 1-antitrypsin deficiency and moderate to severe lung disease

1 reference

12 December 2020

[Guidelines for the diagnosis and management of alpha-1 antitrypsin deficiency]

1 reference

12 December 2020

Alpha1-antitrypsin, old dog, new tricks. Alpha1-antitrypsin exerts in vitro anti-inflammatory activity in human monocytes by elevating cAMP

1 reference

12 December 2020

Alpha-1-antitrypsin (AAT) anomalies are associated with lung disease due to rapidly growing mycobacteria and AAT inhibits Mycobacterium abscessus infection of macrophages

1 reference

12 December 2020

TNF-alpha-induced self expression in human lung endothelial cells is inhibited by native and oxidized alpha1-antitrypsin

1 reference

12 December 2020

Alfa-1-antitrypsin deficiency panniculitis acquired after liver transplant and successfully treated with retransplant

1 reference

12 December 2020

Identifiers

DOI

10.1186/1750-1172-6-14

1 reference

Dimensions Publication ID

5 August 2017

0 references

1 reference

5 August 2017

1 reference