(Q34980697)

5 August 2017

1 reference

title

Sphingosine-1-phosphate: dual messenger functions (English)

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5 August 2017

sphingosine 1-phosphate

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ChEBI release 2020-05-28

3

Sarah Spiegel

1 reference

5 August 2017

Shawn G Payne

1

1 reference

PubMed ID

12401202

5 August 2017

Sheldon Milstien

series ordinal

2

1 reference

PubMed ID

12401202

5 August 2017

language of work or name

English

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publication date

1 October 2002

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5 August 2017

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5 August 2017

531

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5 August 2017

1

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5 August 2017

54-57

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Sphingosine-1-phosphate, a novel lipid, involved in cellular proliferation

5 August 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2903480-4

Diversity of cellular receptors and functions for the lysophospholipid growth factors lysophosphatidic acid and sphingosine 1-phosphate.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2903480-4

Functions of a new family of sphingosine-1-phosphate receptors

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2903480-4

Lysophospholipids--receptor revelations

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2903480-4

The roles of sphingosine-1-phosphate in asthma

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2903480-4

Alteration of lymphocyte trafficking by sphingosine-1-phosphate receptor agonists

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2903480-4

The immune modulator FTY720 targets sphingosine 1-phosphate receptors

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2903480-4

Dual actions of sphingosine-1-phosphate: extracellular through the Gi-coupled receptor Edg-1 and intracellular to regulate proliferation and survival

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2903480-4

Sphingosine-1-phosphate as a ligand for the G protein-coupled receptor EDG-1

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2903480-4

Sphingosine 1-phosphate stimulates cell migration through a G(i)-coupled cell surface receptor. Potential involvement in angiogenesis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2903480-4

Migration of vascular smooth muscle cells induced by sphingosine 1-phosphate and related lipids: potential role in the angiogenic response

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2903480-4

Role of the sphingosine-1-phosphate receptor EDG-1 in PDGF-induced cell motility

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2903480-4

Edg-1, the G protein-coupled receptor for sphingosine-1-phosphate, is essential for vascular maturation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2903480-4

Sphingosine 1-phosphate induces chemotaxis of immature and modulates cytokine-release in mature human dendritic cells for emergence of Th2 immune responses

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2903480-4

Inhibitory regulation of Rac activation, membrane ruffling, and cell migration by the G protein-coupled sphingosine-1-phosphate receptor EDG5 but not EDG1 or EDG3

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2903480-4

G(i)-mediated Cas tyrosine phosphorylation in vascular endothelial cells stimulated with sphingosine 1-phosphate: possible involvement in cell motility enhancement in cooperation with Rho-mediated pathways.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2903480-4

Involvement of phospholipase D in sphingosine 1-phosphate-induced activation of phosphatidylinositol 3-kinase and Akt in Chinese hamster ovary cells overexpressing EDG3.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2903480-4

Sphingosine 1-phosphate protects human umbilical vein endothelial cells from serum-deprived apoptosis by nitric oxide production

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2903480-4

Sphingosine 1-phosphate-induced cell rounding and neurite retraction are mediated by the G protein-coupled receptor H218

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2903480-4

Characterization of a novel sphingosine 1-phosphate receptor, Edg-8

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2903480-4

Nrg-1 belongs to the endothelial differentiation gene family of G protein-coupled sphingosine-1-phosphate receptors

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2903480-4

Vascular endothelial cell adherens junction assembly and morphogenesis induced by sphingosine-1-phosphate

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2903480-4

The novel sphingosine 1-phosphate receptor AGR16 is coupled via pertussis toxin-sensitive and -insensitive G-proteins to multiple signalling pathways.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2903480-4

Marked perinatal lethality and cellular signaling deficits in mice null for the two sphingosine 1-phosphate (S1P) receptors, S1P(2)/LP(B2)/EDG-5 and S1P(3)/LP(B3)/EDG-3.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2903480-4

Involvement of sphingosine kinase in TNF-alpha-stimulated tetrahydrobiopterin biosynthesis in C6 glioma cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2903480-4

Sphingosine-1-phosphate: signaling inside and out.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2903480-4

Sphingosine-1-phosphate as second messenger in cell proliferation induced by PDGF and FCS mitogens

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2903480-4

Role of sphingosine kinase in Ca(2+) signalling by epidermal growth factor receptor

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2903480-4

Activation of sphingosine kinase by tumor necrosis factor-alpha inhibits apoptosis in human endothelial cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2903480-4

Intracellular calcium release mediated by sphingosine derivatives generated in cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2903480-4

Sphingosine kinase expression increases intracellular sphingosine-1-phosphate and promotes cell growth and survival.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2903480-4

Sphingosine kinase: a mediator of vital cellular functions

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2903480-4

Stimulation of nuclear sphingosine kinase activity by platelet-derived growth factor

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2903480-4

Involvement of a pertussis toxin-sensitive G protein in the mitogenic signaling pathways of sphingosine 1-phosphate

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2903480-4

Suppression of ceramide-mediated programmed cell death by sphingosine-1-phosphate

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2903480-4

Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2903480-4

7 January 2021

Ceramide and apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2903480-4

The balance between sphingosine and sphingosine-1-phosphate is decisive for mast cell activation after Fc epsilon receptor I triggering

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2903480-4

Molecular cloning and characterization of a lipid phosphohydrolase that degrades sphingosine-1- phosphate and induces cell death

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2903480-4

Sphingosine 1-phosphate stimulates rat mesangial cell proliferation from outside the cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2903480-4

Antiproliferative properties of sphingosine 1-phosphate in human hepatic myofibroblasts. A cyclooxygenase-2 mediated pathway

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2903480-4

Extracellular export of sphingosine kinase-1 enzyme. Sphingosine 1-phosphate generation and the induction of angiogenic vascular maturation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2903480-4

Stimulation of intracellular sphingosine-1-phosphate production by G-protein-coupled sphingosine-1-phosphate receptors

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2903480-4

Cystic fibrosis transmembrane regulator regulates uptake of sphingoid base phosphates and lysophosphatidic acid: modulation of cellular activity of sphingosine 1-phosphate

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2903480-4

Plasma lipoproteins behave as carriers of extracellular sphingosine 1-phosphate: is this an atherogenic mediator or an anti-atherogenic mediator?

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2903480-4

10.1016/S0014-5793(02)03480-4

7 January 2021

Identifiers

DOI

1 reference

5 August 2017

1 reference

PubMed ID

12401202